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Displaying 3 of 3 results for "ADAT2"
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  1. Crystal structure of human tRNA-specific adenosine-34 deaminase subunit ADAT2 PDB

    ID: PDB:3DH1

    Description: tRNA-specific adenosine deaminase 2 (E.C.3.5.4.-)

  2. Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase BioProject

    ID: PRJNA326260

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. ATorres RNASeq 2015 : Detection of posttranscriptional inosine modification at the precursor tRNA level BioProject

    ID: PRJEB8019

    Keywords: Other

    Access Type: download

    dataset.description: ting on tRNA (hetADAT), composed of two subunits: ADAT2 and ADAT3. Using high-throughput small RNA sequencing, we show that this modification takes place in human tRNAs at the precursor tRNA level and as this precursor maturates. We also functionally validated the human genes encoding for hetADAT and show that in cells, HsADAT2 and HsADAT3 co-localize in nucleus. Lastly, we knocked down HsADAT2 and show for the first time that it is possible to modulate the levels of I34 modification on all human hetADAT tRNA substrates. These findings give mechanistic insights on the biology of tRNA modifications and the tools reporte...

Displaying 3 of 3 results for "ADAT2"