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Displaying 20 of 41 results for "ADAMTS5"
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  1. Crystal structure of ADAMTS5 with inhibitor bound PDB

    ID: PDB:2RJQ

    Description: ADAMTS-5 (E.C.3.4.24.-)

  2. High Resolution Crystal Structure of the Catalytic Domain of ADAMTS-5 (Aggrecanase-2) PDB

    ID: PDB:3B8Z

    Description: protein ADAMTS-5 (E.C.3.4.24.-)

  3. Analysis of Meniscal Degeneration and Meniscal Gene Expression OmicsDI

    ID: E-GEOD-19060

    Date Released: 03-27-2012

    Description: in the disease process of OA. This study sought: 1) to determine the prevalence of meniscal degeneration in OA patients, 2) to examine gene expression in OA meniscal cells compared to normal control meniscal cells, and 3) to test the hypothesis that OA meniscal cells are different from normal meniscal cells. The grades of meniscal degeneration correlated in a positive fashion with the grades of articular cartilage degeneration (r = 0.672; P < 0.0001...

  4. Analysis of Meniscal Degeneration and Meniscal Gene Expression ArrayExpress

    ID: E-GEOD-19060

    Description: in the disease process of OA. This study sought: 1) to determine the prevalence of meniscal degeneration in OA patients, 2) to examine gene expression in OA meniscal cells compared to normal control meniscal cells, and 3) to test the hypothesis that OA meniscal cells are different from normal meniscal cells. The grades of meniscal degeneration correlated in a positive fashion with the grades of articular cartilage degeneration (r = 0.672; P < 0.0001...

  5. Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with Marimastat PDB

    ID: PDB:3HY7

    Description: ---

  6. Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with an Amino-2-indanol compound PDB

    ID: PDB:3HYG

    Description: ---

  7. Analysis of Meniscal Degeneration and Meniscal Gene Expression BioProject

    ID: PRJNA120565

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: in the disease process of OA. This study sought: 1) to determine the prevalence of meniscal degeneration in OA patients, 2) to examine gene expression in OA meniscal cells compared to normal control meniscal cells, and 3) to test the hypothesis that OA meniscal cells are different from normal meniscal cells. The grades of meniscal degeneration correlated in a positive fashion with the grades of articular cartilage degeneration (r = 0.672; P < 0.0001...
  8. Crystal Structure of murine 12F4 Fab monoclonal antibody against ADAMTS5 PDB

    ID: PDB:4X8J

    Description: Light chain, Heavy chain

  9. Crystal Structure of murine 7B4 Fab monoclonal antibody against ADAMTS5 PDB

    ID: PDB:4X80

    Description: IgG1 Light Chain, IgG1 Fab 7B4 Heavy chain

  10. Crystal Structure of ADAMTS4 (apo form) PDB

    ID: PDB:3B2Z

    Description: Crystal Structure of ADAMTS4 with inhibitor bound

  11. Crystal structure of ADAMTS4 with inhibitor bound PDB

    ID: PDB:2RJP

    Description: ADAMTS-4 (E.C.3.4.24.82)

  12. Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with an Amino-2-indanol compound PDB

    ID: PDB:3LJT

    Description: A disintegrin and metalloproteinase with thrombospondin motifs 5 (E.C.3.4.24.-)

  13. Genome-wide maps of HES1 binding-site in human chondrogenic cell. BioProject

    ID: PRJNA257267

    Keywords: Epigenomics

    Access Type: download

    dataset.description: elements of Hes1 around gene loci of Mmp13 and Adamts5, which were catabolic enzymes of cartilage matrix. Overall design: Examination of HES1 binding site in human chondrogenic SW1353 cells....
  14. Genome-wide maps of HES1 binding-site in human chondrogenic cell ArrayExpress

    ID: E-GEOD-60006

    Description: elements of Hes1 around gene loci of Mmp13 and Adamts5, which were catabolic enzymes of cartilage matrix. Examination of HES1 binding site in human chondrogenic SW1353 cells....

  15. from: Association between COL11A1 (rs1337185) and ADAMTS5 (rs162509) gene polymorphisms and lumbar spine pathologies in Chinese Han population: an observational study... Dryad

    DateIssued: 04-05-2017

    Description: bgroups, including disc herniation only (Subgroup 1), discopathies or/and osteochondrosis associated with disc herniation (Subgroup 2), spinal stenosis or/and spondylolisthesis (Subgroup 3), and degenerative scoliosis (Subgroup 4). This study was conducted by examining 2 aspects: environmental factors and SNP genotyping. The environmental factors were evaluated with a questionnaire survey including questions about BMI, smoking habits, the physical demands of their job and exposure to vibrations. Rs1337185, rs5275, rs5277, rs7575934, rs3213718 and rs162509 were genotyped using a PCR-based Invader assay. Results: The physical ...

  16. ATS5_BOVIN UniProt:Swiss-Prot

    ID: Q9TT92

    Description: A disintegrin and metalloproteinase with thrombospondin motifs 5 Peptidase M12B Disintegrin TSP type-

  17. Transcription profiling by array of rats with surgically induced knee osteoarthritis ArrayExpress

    ID: E-GEOD-8077

    Description: thogenesis. METHODS: OA was surgically induced in 5 rats by anterior cruciate ligament transection and partial medial meniscectomy. Sham surgery was performed in 5 additional animals, which were used as controls. Both groups underwent 4 weeks of forced mobilization, 3 times per week. RNA was extracted directly from articular chondrocytes in the OA (operated), contralateral, and sham-operated knees. Affyme...

  18. Global analyses of gene expression in early experimental knee osteoarthritis BioProject

    ID: PRJNA100915

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: thogenesis. METHODS: OA was surgically induced in 5 rats by anterior cruciate ligament transection and partial medial meniscectomy. Sham surgery was performed in 5 additional animals, which were used as controls. Both groups underwent 4 weeks of forced mobilization, 3 times per week. RNA was extracted directly from articular chondrocytes in the OA (operated), contralateral, and sham-operated knees. Affyme...
  19. Epigenomic Analysis of Aberrantly Methylated Genes in Colorectal Cancer ArrayExpress

    ID: E-GEOD-17648

    Description: affected by methylation was the class associated with the cadherin signaling pathway. In comparison with genome-wide expression array, mRNA expression was more like to be down-regulated in the genes demonstrating promoter hypermethylation, although this was not statistically significant. We validated 10 CpG sites that were shown to be hypermethylated in the array studies (ADHFE1, BOLL, SLC6A15, ADAMTS5, TFPI2, EYA4, NPY, TWIST1, LAMA1, GAS7) and 2 CpG sites showing hypomethylaion (MAEL, SFT2D3) in CRC compared to normal mucosa using pyrosequencing. The methylation status measured by pyrosequencing was consistent with the methylation array data. In conclusion, we have shown that methylation profiling based on beadchip arrays is an effective method for screening for aberrantly methylated genes in CRC. In addition, we identified no...

  20. Transcription profiling by array of rats with surgically induced knee osteoarthritis OmicsDI

    ID: E-GEOD-8077

    Date Released: 04-30-2015

    Description: thogenesis. METHODS: OA was surgically induced in 5 rats by anterior cruciate ligament transection and partial medial meniscectomy. Sham surgery was performed in 5 additional animals, which were used as controls. Both groups underwent 4 weeks of forced mobilization, 3 times per week. RNA was extracted directly from articular chondrocytes in the OA (operated), contralateral, and sham-operated knees. Affyme...


Displaying 20 of 41 results for "ADAMTS5"