Crystal structure of human Acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in a complex with CoA PDB

ID: PDB:3GPC

Description: Acyl-coenzyme A synthetase ACSM2A (E.C.6.2.1.2)

Crystal structure of human acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in complex with ATP PDB

ID: PDB:3C5E

Description: Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor (E.C.6.2.1.2)

Crystal structure of human acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in complex with AMP-CPP PDB

ID: PDB:3DAY

Description: Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor (E.C.6.2.1.2)

Crystal structure of human acyl-CoA synthetase medium-chain family member 2A, with L64P mutation PDB

ID: PDB:3B7W

Description: Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor (E.C.6.2.1.2)

Crystal structure of human acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in a ternary complex with products PDB

ID: PDB:3EQ6

Description: Acyl-coenzyme A synthetase ACSM2A (E.C.6.2.1.2)

CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN COMPLEX WITH AMP PDB

ID: PDB:2VZE

Description: ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL (E.C.6.2.1.2)

CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN COMPLEX WITH IBUPROFEN PDB

ID: PDB:2WD9

Description: ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL (E.C.6.2.1.2)

Aberrant choline metabolism in epithelial ovarian cancer: relevance of choline kinase activity and expression ArrayExpress

ID: E-GEOD-39943

Description: ) related to inflammation and EOC aggressiveness. Acyl-CoA synthetase medium-chain family member 3 (ACSM3), phosphatidic acid phosphatase type 2 (PPAP2A) and Osteoprotegerin were among the most up-regulated genes. All co-modulated genes have been validated by RTqPCR also in independent biological replicates. Ingenuity System Pathways Analysis (IPA) identified a network of molecules most significantly affected by CHKA silencing whose main functions is related to cell morphology cellular assembly and organization, cellular function and maintenance. Also, the cellular functions predicted to be mostly affected by silencing were cellular movement and cell death that are expected to be respectively decreased and increased in silenced cells. a total of 12 samples were analyzed: Two EOC cell line SKOV3 and INTOV11 were transiently silenced with unrelated or CHKA-specific siRNA pool. Three independent experiment were run for each cell line....