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Displaying 20 of 109 results for "ACLY"
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  1. Expression data by ACLY knockdown ArrayExpress

    ID: E-GEOD-37243

    Description: c targets. RNA interference-mediated depletion of ATP citrate lyase (ACLY), the enzyme that catalyzes the first step of de novo lipogenesis, leads to growth suppression in a subset of human cancer cells. Here we demonstrate the molecular basis and potential biomarkers fo...

  2. ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate ArrayExpress

    ID: E-GEOD-61286

    Description: tion of acetyl-CoA carboxylase (ACACA or ACC1) or ATP citrate lyase (ACLY) protected cancer cells from hypoxia-induced apoptosis. Additionally, loss of ACLY or ACC1 reduced levels and activities of the oncogenic transcription factor ETV4. Silencing ETV4 also protected cells from hypoxia-induced apoptosis and led to remarkably similar transcriptional responses as with silenced ACLY or ACC1, including an anti-apoptotic program. Metabolomi...

  3. Expression data by ACLY knockdown BioProject

    ID: PRJNA159187

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. Truncated Human ATP-Citrate Lyase with Citrate Bound PDB

    ID: PDB:3MWD

    Description: ATP-citrate synthase (E.C.2.3.3.8)

  5. Truncated Human ATP-Citrate Lyase with Tartrate Bound PDB

    ID: PDB:3MWE

    Description: ATP-citrate synthase (E.C.2.3.3.8)

  6. ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate BioProject

    ID: PRJNA260670

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Acetyl-CoA metabolism by ACSS2 regulates neuronal histone acetylation and long-term memory [RNA-seq] BioProject

    ID: PRJNA308763

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: eurons following lentiviral knockdown of ACSS2 or ATP citrate lyase (ACL) (and control = scramble hairpin); survey of hippocampal gene expression changes associated with retrieval of fear memory, after ACSS2-AAV knockdown or in EGFP-AAV control (comparison of 0h vs. 1h post-memory retrieval)....
  8. Acetyl-CoA metabolism by ACSS2 regulates neuronal histone acetylation and long-term memory [RNA-seq] ArrayExpress

    ID: E-GEOD-76853

    Description: eurons following lentiviral knockdown of ACSS2 or ATP citrate lyase (ACL) (and control = scramble hairpin); survey of hippocampal gene expression changes associated with retrieval of fear memory, after ACSS2-AAV knockdown or in EGFP-AAV control (comparison of 0h vs. 1h post-memory retrieval)....

  9. Truncated human atp-citrate lyase with ADP and tartrate bound PDB

    ID: PDB:3PFF

    Description: ATP-citrate synthase (E.C.2.3.3.8)

  10. Expression data by ACLY knockdown OmicsDI

    ID: E-GEOD-37243

    Date Released: 06-02-2014

    Description: c targets. RNA interference-mediated depletion of ATP citrate lyase (ACLY), the enzyme that catalyzes the first step of de novo lipogenesis, leads to growth suppression in a subset of human cancer cells. Here we demonstrate the molecular basis and potential biomarkers fo...

  11. ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate OmicsDI

    ID: E-GEOD-61286

    Date Released: 12-11-2015

    Description: tion of acetyl-CoA carboxylase (ACACA or ACC1) or ATP citrate lyase (ACLY) protected cancer cells from hypoxia-induced apoptosis. Additionally, loss of ACLY or ACC1 reduced levels and activities of the oncogenic transcription factor ETV4. Silencing ETV4 also protected cells from hypoxia-induced apoptosis and led to remarkably similar transcriptional responses as with silenced ACLY or ACC1, including an anti-apoptotic program. Metabolomi...

  12. hydrothermal vent metagenome : The Structure of Bacterial Communities and Its Chemoautotrophic Players in Sulfur-rich Sediments of Shallow Water HTVs ... BioProject

    ID: PRJNA305844

    Keywords: targeted loci environmental

    Access Type: download

    dataset.description: bM, respectively] and the rTCA cycle (key enzyme: ATP citrate lyase: genes aclB), will be studied to evaluate the autotrophic potential of vent communities....
  13. cr237_dryad.bed Dryad

    DateIssued: 05-02-2017

    Description: Plink binary format .bed file for 237 labrador retrievers phenotyped for ACL rupture

  14. cr237_dryad.bim Dryad

    DateIssued: 05-02-2017

    Description: Plink binary format .bim file for 237 Labrador retrievers phenotyped for ACL rupture

  15. Expression data from Cerebral Cortex or Hippocampus of COX-1 or COX-2 null mice GEMMA

    ID: 374

    Keywords: functional genomics

    Description: X-1-/-) or COX-2 (COX-2-/-). Expression of lipid (ATP citrate lyase, acetyl-CoA acetyltransferase, hydroxyacyl-CoA dehydrogenase) and homocysteine (methionine adenosyltransferase, S-adenosylhomocysteine hydrolase) metabolism genes was increased in the cerebral cortex of COX-2 -/- mice. Further, expression of GABAergic neurotransmission genes (GABA transporter 3, GABA-A receptor subunit ?1) was altered in the cerebra...

  16. cr237_dryad.fam Dryad

    DateIssued: 05-02-2017

    Description: Plink binary format fam file for 237 Labrador retrievers phenotyped for ACL rupture. 1= unaffected, 2 = affected

  17. Expression data from Cerebral Cortex or Hippocampus of COX-1 or COX-2 null mice BioProject

    ID: PRJNA96197

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: X-1-/-) or COX-2 (COX-2-/-). Expression of lipid (ATP citrate lyase, acetyl-CoA acetyltransferase, hydroxyacyl-CoA dehydrogenase) and homocysteine (methionine adenosyltransferase, S-adenosylhomocysteine hydrolase) metabolism genes was increased in the cerebral cortex of COX-2 -/- mice. Further, expression of GABAergic neurotransmission genes (GABA transporter 3, GABA-A receptor subunit ?1) was altered in the cerebra...
  18. Effect of donor age on the proportion of mesenchymal stem cells derived from anterior cruciate ligaments BioProject

    ID: PRJNA255890

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Analysis of gene expression profiles of ACL-MSCs derived from total knee arthroplasty (TKA) and ACL reconstruction patients. We hypothesized that the pr...
  19. Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide BioProject

    ID: PRJNA322550

    Keywords: Transcriptome or Gene expression

    Access Type: download

  20. ACLY_SHEEP UniProt:Swiss-Prot

    ID: Q2TCH3

    Description: ATP-citrate synthase ATP-grasp ATP ATP


Displaying 20 of 109 results for "ACLY"