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Displaying 20 of 84 results for "ABCA1"
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  1. Cryo-EM structure of human ABCA1 PDB

    ID: PDB:5XJY

    Description: ATP-binding cassette sub-family A

  2. Expression data from hepatocytes of Tangier disease and control subjects BioProject

    ID: PRJNA377252

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. PRJNA347616 BioProject

    Keywords: raw sequence reads

    Access Type: download

    dataset.description: share the same genome duplication event (known as TGD or 3R). To understand how fish genomes evolved after whole genome duplication, genomic DNA from a range of osteoglossomorph fish was sequenced....
  4. freshwater metagenome : Ammonia oxizidizing archaea and bacteria Metagenome BioProject

    ID: PRJNA196465

    Keywords: metagenome

    Access Type: download

    dataset.description: AOA and AOB behind the TGD - from water in the Yangtze River behind the Three Gorges Dam and also bank soils/sediments.
  5. Gene expression series from murine liver samples comparing ABCA1 over-expression in LDL receptor -/- genetic background BioProject

    ID: PRJNA96137

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. ription profiling of livers from mice overexpress ABCA1 in LDL receptor -/- genetic background to characterize the effects of ABCA1 overexpression... ArrayExpress

    ID: E-GEOD-5496

    Description: Changes in the transcript profile due to ABCA1 expression in murine liver samples was evaluated in LDL receptor -/- genetic backgrounds. Experiment Overall Design: Case (

  7. ription profiling of livers from mice overexpress ABCA1 in LDL receptor -/- genetic background to characterize the effects of ABCA1 overexpression.... OmicsDI

    ID: E-GEOD-5496

    Date Released: 03-27-2012

    Description: Changes in the transcript profile due to ABCA1 expression in murine liver samples was evaluated in LDL receptor -/- genetic backgrounds. Experiment Overall Design: Case (

  8. Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1 BioProject

    ID: PRJNA152789

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. Transcription profiling of mouse embryonic stem (ES) cells to study the effect of Abca1 +/- mutations in ES cells ArrayExpress

    ID: E-GEOD-614

    Description: effect of +/- mutations in ES cells

  10. Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1 ArrayExpress

    ID: E-GEOD-35401

    Description: ed from 3 biological replicate sets of PrEC, RWPE-1, DU 145, and LNCaP cells. This Series represents the gene expression profiling data only. The methyl-Seq data were submitted directly to SRA and are represented by accession SRA049689.1....

  11. Transcription profiling of mouse embryonic stem (ES) cells to study the effect of Abca1 +/- mutations in ES cells. OmicsDI

    ID: E-GEOD-614

    Date Released: 03-27-2012

    Description: effect of +/- mutations in ES cells

  12. Effect of LXR activation on LPS-induced inflammatory response in immortalized bone marrow macrophages from LXRa/b knockout mice stably expressing LXR ... BioProject

    ID: PRJNA288720

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: eover, we identify the putative lipid transporter ABCA1 as a critical mediator of LXR’s anti-inflammatory effects. Ligand activation of LXR inhibits signaling from TLR4 to its downstream NF-κB and MAPK effectors through ABCA1-dependent changes in membrane lipid composition and organization that disrupt the recruitment of MyD88 and TRAF6. These data suggest that a common mechanism–direct transcriptional activation–underlies the dual biological functions of LXRs in metabolism and inflammation. Overall design: Cells were placed in DMEM containing 0.5% FBS, 5 μM simvastatin, 100 μM mevalonic acid and 1μM GW3965 or DMSO overnight. Cells were then stimulated with 10ng/ml LPS or vehicle for...
  13. Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1 OmicsDI

    ID: E-GEOD-35401

    Date Released: 06-02-2014

    Description: ed from 3 biological replicate sets of PrEC, RWPE-1, DU 145, and LNCaP cells. This Series represents the gene expression profiling data only. The methyl-Seq data were submitted directly to SRA and are represented by accession SRA049689.1....

  14. MicroRNA-27a regulates lipid metabolism and inhibits hepatitis C virus replication in human hepatoma cells ArrayExpress

    ID: E-GEOD-41737

    Description: ptional factor, RXRα, and the lipid transporter, ABCA1 Carrying out a Target Scan (Release 5.2) of miR-27a predicted 921 candidate target genes, and functional gene ontology enrichment analysis of these genes by MetaCore (Thomson Reuters, NY) showed that miR-27a could target the signaling pathways of cytoskeleton remodeling and lipid metabolism . To examine whether these signaling pathways were regulated by miR-27a, gene expression profiling was carried out in Huh-7.5 cells in which miR-27a was over- or under-expressed. Transfection of cells with pre-miR-27a and pre-miR-control, or anti-miR-27a and anti-miR-control enabled down- and up-regulated genes to be determined, respectively. Huh-7.5 cells with miR-27a over- or under-expressed...

  15. Effect of LXR activation on LPS-induced inflammatory response in primary bone marrow macrophages from ABCA1fl/fl LysM Cre and control wildtype mice BioProject

    ID: PRJNA288719

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: eover, we identify the putative lipid transporter ABCA1 as a critical mediator of LXR’s anti-inflammatory effects. Ligand activation of LXR inhibits signaling from TLR4 to its downstream NF-κB and MAPK effectors through ABCA1-dependent changes in membrane lipid composition and organization that disrupt the recruitment of MyD88 and TRAF6. These data suggest that a common mechanism–direct transcriptional activation–underlies the dual biological functions of LXRs in metabolism and inflammation. Overall design: Cells were placed in DMEM containing 0.5% FBS, 5 μM simvastatin, 100 μM mevalonic acid and 1μM GW3965 or DMSO overnight. Cells were then stimulated with 10ng/ml LPS or vehicle for...
  16. effect of +/- mutations in ES cells GEMMA

    ID: 107

    Keywords: functional genomics

    Description: s affecting cholesterol transport and metabolism. Abca1 +/- and Cdk4 +/- ES lines compared with controls.....

  17. American Crocodile Juvenile Growth and Survival Dryad

    DateIssued: 04-21-2011

    Description: Design and develop a monitoring program for growth and survival of crocodiles in areas that will be affected by CERP projects and conduct surveys for ...

  18. NHLBI GO-ESP: Family Studies (Mendelian Lipid Disorders) dbGaP

    ID: phs000587.v1.p1

    Description: d Opportunity" Exome Sequencing Project (GO-ESP), a signature project of the NHLBI Recovery Act investment, was designed to identify genetic variants in coding regions (exons) of the human genome ...

    Study Types: Case Set

  19. TERRITORIAL POLICIES AND REGIONAL GROWTH : TOWARDS THE EMERGENCE OF A NEW CENTER-PERIPHERY MODEL (THE CASE OF TANGIER) Figshare

    ID: doi:10.6084/M9.FIGSHARE.1036503

    Release Date: 07-04-2014

    Description:

  20. TERRITORIAL POLICIES AND REGIONAL GROWTH : TOWARDS THE EMERGENCE OF A NEW CENTER-PERIPHERY MODEL (THE CASE OF TANGIER) Figshare

    ID: doi:10.6084/M9.FIGSHARE.1036503.V1

    Release Date: 01-19-2016

    Description:


Displaying 20 of 84 results for "ABCA1"