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  1. The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer's disease OmicsDI

    ID: E-GEOD-66598

    Date Released: 01-03-2016

    Description: Alzheimer’s disease (AD) is a neurodegenerative disease characterized by a marked decline in cognition and memory formation. Increasing evidence hig...

  2. Lung miRNA profiling in mouse model of allergic airways disease OmicsDI

    ID: E-GEOD-72793

    Date Released: 01-03-2016

    Description: To determine the differential expression of miRNAs in the lungs of mice subjected to a model of allergic airways disease and non-allergic and steroid-...

  3. Human induced pluripotent stem cells derived from a sporadic Alzheimer's disease patient OmicsDI

    ID: E-GEOD-31163

    Date Released: 01-02-2016

    Description: Induced pluripotent stem cell (iPSC) disease models have been generated for a number of diseases, and some have shown their potential utilization for ...

  4. Identification of MEDIATOR16 as the Arabidopsis COBRA suppressor, MONGOOSE1   OmicsDI

    ID: E-GEOD-75199

    Date Released: 01-03-2016

    Description: RNAseq data for Col-0. cob-6, sfr6-3 and cob-6sfr6-3 7 days old seedlings grown in 24h light with 0

  5. Oct4 binding and Histone modification profiling during OSKM-mediated 2nd reprogramming OmicsDI

    ID: E-GEOD-67520

    Date Released: 01-03-2016

    Description: Forced expression of four transcription factors Oct4,Sox2, Klf4 and Myc (OSKM) induces somatic cell reprogramming towards pluripotency. Major efforts ...

  6. Streptococcus suis 05ZY: control vs contact with hBMEC 1 h OmicsDI

    ID: E-GEOD-46961

    Date Released: 01-02-2016

    Description: The interactions of Streptocococcus suis (S.suis) with human microvascular endothelial cells (hBMEC) are important process for S.suis passage across h...

  7. Expression data from OSKM-mediated 2nd reprogramming cells and the corresponding iPS cell line OmicsDI

    ID: E-GEOD-67462

    Date Released: 01-03-2016

    Description: Forced expression of four transcription factors Oct4,Sox2, Klf4 and Myc (OSKM) induces somatic cell reprogramming towards pluripotency. Major efforts ...

  8. Cryptochromes interact directly with PIFs to control plant growth in limiting blue light OmicsDI

    ID: E-GEOD-68193

    Date Released: 01-01-2016

    Description: Sun-loving plants have the ability to detect and avoid shading through sensing of both blue and red light wavelengths. Higher plant cryptochromes (CRY...

  9. BCOR controls maintenance of haematopoietic stem cell quiescence and regulates myeloid cell proliferation and differentiation [Illumina] OmicsDI

    ID: E-GEOD-69620

    Date Released: 01-01-2016

    Description: BCOR is a component of a variant Polycomb group repressive complex 1 (PRC1) complex. Recently, we and others reported recurrent somatic BCOR loss-of-f...

  10. Vascular niche induction of hematopoietic progenitors from pluripotent stem cells OmicsDI

    ID: E-GEOD-64644

    Date Released: 01-01-2016

    Description: Pluripotent stem cells (PSC) represent an alternative source of hematopoietic stem cells (HSCs). Clinical translation is impeded by limited engraftmen...

  11. Integrating high-dimensional transcriptomics and image analysis tools into early safety screening (II) OmicsDI

    ID: E-GEOD-70613

    Date Released: 01-02-2016

    Description: In this paper we demonstrated the potential to flag toxicity issues by utilizing data from exploratory experiments which are typically generated for t...

  12. Mdm2 enhances stemness-promoting chromatin modifications through the Polycomb Repressor Complex 2 in a p53-Independent Manner [hMSC microarray] OmicsDI

    ID: E-GEOD-73601

    Date Released: 01-02-2016

    Description: The Mdm2 oncoprotein ubiquitinates and antagonizes p53 but may also carry out p53-independent functions. Here we report that Mdm2 is required for the ...

  13. Models of Human Core Transcriptional Regulatory Circuitries OmicsDI

    ID: E-GEOD-76181

    Date Released: 12-27-2015

    Description: A small set of core transcription factors (TFs) dominates control of the gene expression program in embryonic stem cells and other well-studied cellul...

  14. G72 overexpression in U87 cells OmicsDI

    ID: E-GEOD-67704

    Date Released: 01-01-2016

    Description: G72 is a susceptible gene for schizophrenia. No matter genetic variation or serum levels, G72 has been recognized as a biomarker for schizophrenia. In...

  15. The effects of aging on circadian patterns of gene expression in the human prefrontal cortex OmicsDI

    ID: E-GEOD-71620

    Date Released: 01-02-2016

    Description: With aging, significant changes in circadian rhythms occur, including a shift in phase toward a “morning” chronotype and a loss of rhythmicity in ...

  16. ERK activation, gene dysregulations and cell transformation at submicromolar doses of Cr6+ in C3H10T1/2 and BALB/c 3T3 cells: interaction with Lipoic ... OmicsDI

    ID: E-GEOD-43156

    Date Released: 01-02-2016

    Description: The molecular mechanism of Cr6+ carcinogenicity is not well understood. Studies advocate a key involvement of the altered cytogenomics and dysregulate...

  17. The homeobox transcription factor Nkx2-1 regulates microRNAs controlling downstream gene silencing in lung epithelial cells (mRNA) OmicsDI

    ID: E-GEOD-47054

    Date Released: 12-26-2015

    Description: Cell-specific gene expression is achieved by a combination of mechanisms including transcriptional and post-transcriptional regulation. The transcript...

  18. Synergistic activity of BET protein antagonist-based combinations in Mantle Cell Lymphoma cells sensitive or resistant to ibrutinib OmicsDI

    ID: E-GEOD-70651

    Date Released: 01-02-2016

    Description: To determine the global transcriptome changes in mantle cell lymphoma cells following treatment with the BET bromodomain antagonist, JQ1 Mantle Cell L...

  19. Hormetic shifting of redox environment by the ROS-producing polyphenol resveratrol protects cells from oxidative stress OmicsDI

    ID: E-GEOD-72119

    Date Released: 01-02-2016

    Description: Resveratrol is a natural product that has gained tremendous interest due to multiple reported health-beneficial effects. However, the underlying mecha...

  20. CodeLink Mouse Whole Genome Bioarray data from hematopoietic stem cells (HSCs) of miR-125a (+/+) wild-type and miR-125a knockout mice with myeloprolif... OmicsDI

    ID: E-GEOD-69621

    Date Released: 01-01-2016

    Description: miR-125a knockout mice develop myeloproliferative disorder (MPD). To investigate the molecular mechanisms of MPD induced by the loss of miR-125a, gene...

Displaying 20 of 78,201 results for " "