Comparative analysis of the amorfrutin A and rosiglitazone (Rosi)-dependent hepatic transcriptomes in a mouse model of diet-induced obesity NURSA

Keywords: whole liver

Description: Male C57BL/6 mice at 6 weeks of age were fed a HFD (60% of calories as fat) for 12 weeks to induce obesity and insulin resistance. Subsequently mice w...

ID: 10.1621/Iw9Fidj7Hn

Analysis of the estrogen-related receptor β (ERRβ/ESRRB) and DY131-regulated transcriptome in human DU145 prostate cancer cells NURSA

Keywords: epithelium DU145 cells

Description: Human DU145 prostate cancer cells stably transfected with an ERRβ/ESRRB expression vector or an empty vector control were treated for 12 h with 3 µM...

ID: 10.1621/KhoLDn0eUQ

Chronic time course and dose-dependence analysis of the clofibrate (Clofib)-regulated transcriptome in rat liver NURSA

Keywords: whole liver

Description: Livers were isolated from rats treated for 4 - 29 d with or without 30 - 300 mg/kg bw/d Clofib.

ID: 10.1621/N4Z6Zseri5

Analysis of the 17β-estradiol (17βE2)-regulated transcriptome in rat trigeminal ganglia NURSA

Keywords: trigeminal ganglia whole

Description: Cultured trigeminal ganglia from 8 week old random cycling female rats were 17βE2-deprived then treated for 24 h with or without 1 nM 17βE2.

ID: 10.1621/gWBqfhz6yG

Comparative analysis of the 17β-estradiol (17βE2)-, genistein (Gen)-, and phytoestrogen (S-equol [Sequol] and liquiritigenin [Liquir])-regulated, es... NURSA

Keywords: epithelium MCF-7 cells

Description: Human MCF-7 breast cancer cells were infected for 72 h with (i) control adenovirus expressing β-gal; (ii) adenovirus expressing ERβ/ESR2; or (ii) ad...

ID: 10.1621/0xZtJIMQg2

Analysis of the Ssfa2-dependent transcriptome in mouse liver NURSA

Keywords: whole liver

Description: Liver was isolated from 32 week old C57BL6/J male Ssfa2 KO and WT mice fed a normal chow diet.

ID: 10.1621/NCM4UKSDLs

Analysis of the Bromo Adjacent Homology Domain Containing 1 (Bahd1)-dependent transcriptome in mouse E16.5 placenta and liver NURSA

Keywords: whole liver

Description: Placenta and liver tissue was isolated at embryonic day 16.5 from male and female Bahd1 knockout and wild-type mice.

ID: 10.1621/FPygkhLBsO

Tissue-specific expression patterns of nuclear receptor coregulators NURSA

Keywords:

Description: C57/Bl6J and 129x1/SvJ male or female mice (n = 6) at 8-9 weeks of age from each strain were sacrificed at lights-on (ZT0) by halothane inhalation (Ha...

ID: 10.1621/datasets.04002

Acute time course and dose-dependence analysis of the clofibrate (Clofib)-regulated transcriptome in rat liver NURSA

Keywords: whole liver

Description: Livers were isolated from rats treated for 3 - 24 h with or without 30 mg - 300 mg/kg bw/d Clofib.

ID: 10.1621/39jyLTZloo

Analysis of the GW501516 (GW1516)-regulated transcriptome in primary human macrophages expressing constitutively active AMPK NURSA

Keywords: myeloid lineage macrophages monocyte-derived

Description: Primary human macrophages transduced with constitutively active (T172A) AMPK α1 variant were treated for 24 h with or without 100 nM GW1516.

ID: 10.1621/2w9z81daL1

Analysis of the dihydrotestosterone (DHT)-regulated transcriptome in human LNCaP-C4-2B prostate cancer cells NURSA

Keywords: epithelium LNCaP-C4-2B cells

Description: Human LNCaP-C4-2B prostate cancer cells were treated with for 16 h with or without 10 nM DHT.

ID: 10.1621/mpN8PDaTeM

Time course and dose dependence analysis of the bisphenol A (BPA)-regulated transcriptome in Ishikawa cells NURSA

Keywords: endometrium epithelium Ishikawa cells

Description: Human Ishikawa endometrial carcinoma cells were treated with or without 1 nM, 100 nM, 10 µM or 100 µM BPA for 8 h, 24 h or 48 h.

ID: 10.1621/CwEZYldrxg

Time course transcriptomic analysis of rosiglitazone (Rosi)-treated C3H/10T1/2 cells NURSA

Keywords: WAT adipocytes C3H/10T1/2 cell-derived

Description: Fully differentiated C3 h/10T1/2 adipocytes were cultured with 1 µM Rosi or vehicle for 1 h.

ID: 10.1621/hLnw2RmSWG

Mutational analysis of the peroxisome proliferator activated receptor-γ coactivator 1- β (PGC1β/Ppargc1b)-regulated transcriptome in mouse liver an... NURSA

Keywords: whole liver

Description: Liver and skeletal muscle were isolated from C5BL/6 wild type mice or mice expressing a mutant form of PGC1β/Ppargc1b lacking two out of the three LX...

ID: 10.1621/d4Kt4gB72O

Dose dependent analysis of the rosiglitazone (Rosi)-regulated liver and inguinal adipose tissue transcriptomes in the Leprdb null mutant mouse NURSA

Keywords: whole liver

Description: Liver or inguinal adipose tissue was collected from male BKS.Cg-m +/+ Leprdb/J mice treated with or without Rosi at a range of doses for 18 days. The...

ID: 10.1621/9IFwN8xkBn

Analysis of the 17β-estradiol (17βE2) dependent transcriptome in SUM44PE invasive lobular carcinoma breast cancer cell lines NURSA

Keywords: epithelium SUM44PE cells

Description: SUM44PE invasive lobular carcinoma breast cancer cell lines were treated with 1 nM 17βE2 or vehicle for 3 h and 24 h.

ID: 10.1621/6ugTmHZK5X

Transcriptomic analysis of progesterone (P4)-treated mouse ovary NURSA

Keywords: Female reproductive ovary whole

Description: Newborn Sprague-Dawley rat ovaries dissected from pups less than 8 h old, were cultured in the presence or absence of 1 µM P4 for 48 h.

ID: 10.1621/lbPzmF6Pwq

Analysis of the dexamethasone (Dex)- and testosterone (Test)-regulated transcriptomes in rat gastrocnemius muscle NURSA

Keywords: gastrocnemius whole

Description: Gastrocnemius muscle was isolated from male Wistar-Hannover rats treated with or without a combination of 0.7 mg/kg/d Dex and 28 mg/kg/d Test for 7 da...

ID: 10.1621/9MncYfbHNA

Analysis of the androgen receptor (AR) and dihydrotestosterone (DHT)-regulated transcriptomes in normal (LNCaP) and androgen-independent (LNCaP-abl) c... NURSA

Keywords: epithelium LNCaP cells

Description: Human LNCaP or LNCaP-abl prostate cancer cells were transfected with AR siRNA or scrambled control siRNA for 72 h. LNCaP-abl cells were also treated w...

ID: 10.1621/UhiFZHfzQW

Analysis of the Nur77/Nr4a1-regulated transcriptome in pyramidal neurons NURSA

Keywords: hippocampus pyramidal neurons

Description: After 10 days in culture, dissociated mouse hippocampal pyramidal neurons were infected with lentivirus expressing Nur77/Nr4a1 or GFP for 6 d.

ID: 10.1621/pDfF4bWOiY