Comparative analysis of the amorfrutin A and rosiglitazone (Rosi)-dependent hepatic transcriptomes in a mouse model of diet-induced obesity NURSA
Keywords: whole liver
Description: Male C57BL/6 mice at 6 weeks of age were fed a HFD (60% of calories as fat) for 12 weeks to induce obesity and insulin resistance. Subsequently mice w...
ID: 10.1621/Iw9Fidj7Hn
Analysis of the estrogen-related receptor β (ERRβ/ESRRB) and DY131-regulated transcriptome in human DU145 prostate cancer cells NURSA
Keywords: epithelium DU145 cells
Description: Human DU145 prostate cancer cells stably transfected with an ERRβ/ESRRB expression vector or an empty vector control were treated for 12 h with 3 µM...
ID: 10.1621/KhoLDn0eUQ
Chronic time course and dose-dependence analysis of the clofibrate (Clofib)-regulated transcriptome in rat liver NURSA
Keywords: whole liver
Description: Livers were isolated from rats treated for 4 - 29 d with or without 30 - 300 mg/kg bw/d Clofib.
ID: 10.1621/N4Z6Zseri5
Analysis of the 17β-estradiol (17βE2)-regulated transcriptome in rat trigeminal ganglia NURSA
Keywords: trigeminal ganglia whole
Description: Cultured trigeminal ganglia from 8 week old random cycling female rats were 17βE2-deprived then treated for 24 h with or without 1 nM 17βE2.
ID: 10.1621/gWBqfhz6yG
Comparative analysis of the 17β-estradiol (17βE2)-, genistein (Gen)-, and phytoestrogen (S-equol [Sequol] and liquiritigenin [Liquir])-regulated, es... NURSA
Keywords: epithelium MCF-7 cells
Description: Human MCF-7 breast cancer cells were infected for 72 h with (i) control adenovirus expressing β-gal; (ii) adenovirus expressing ERβ/ESR2; or (ii) ad...
ID: 10.1621/0xZtJIMQg2
Analysis of the Ssfa2-dependent transcriptome in mouse liver NURSA
Keywords: whole liver
Description: Liver was isolated from 32 week old C57BL6/J male Ssfa2 KO and WT mice fed a normal chow diet.
ID: 10.1621/NCM4UKSDLs
Analysis of the Bromo Adjacent Homology Domain Containing 1 (Bahd1)-dependent transcriptome in mouse E16.5 placenta and liver NURSA
Keywords: whole liver
Description: Placenta and liver tissue was isolated at embryonic day 16.5 from male and female Bahd1 knockout and wild-type mice.
ID: 10.1621/FPygkhLBsO
Tissue-specific expression patterns of nuclear receptor coregulators NURSA
Keywords:
Description: C57/Bl6J and 129x1/SvJ male or female mice (n = 6) at 8-9 weeks of age from each strain were sacrificed at lights-on (ZT0) by halothane inhalation (Ha...
ID: 10.1621/datasets.04002
Acute time course and dose-dependence analysis of the clofibrate (Clofib)-regulated transcriptome in rat liver NURSA
Keywords: whole liver
Description: Livers were isolated from rats treated for 3 - 24 h with or without 30 mg - 300 mg/kg bw/d Clofib.
ID: 10.1621/39jyLTZloo
Analysis of the GW501516 (GW1516)-regulated transcriptome in primary human macrophages expressing constitutively active AMPK NURSA
Keywords: myeloid lineage macrophages monocyte-derived
Description: Primary human macrophages transduced with constitutively active (T172A) AMPK α1 variant were treated for 24 h with or without 100 nM GW1516.
ID: 10.1621/2w9z81daL1
Analysis of the dihydrotestosterone (DHT)-regulated transcriptome in human LNCaP-C4-2B prostate cancer cells NURSA
Keywords: epithelium LNCaP-C4-2B cells
Description: Human LNCaP-C4-2B prostate cancer cells were treated with for 16 h with or without 10 nM DHT.
ID: 10.1621/mpN8PDaTeM
Time course and dose dependence analysis of the bisphenol A (BPA)-regulated transcriptome in Ishikawa cells NURSA
Keywords: endometrium epithelium Ishikawa cells
Description: Human Ishikawa endometrial carcinoma cells were treated with or without 1 nM, 100 nM, 10 µM or 100 µM BPA for 8 h, 24 h or 48 h.
ID: 10.1621/CwEZYldrxg
Time course transcriptomic analysis of rosiglitazone (Rosi)-treated C3H/10T1/2 cells NURSA
Keywords: WAT adipocytes C3H/10T1/2 cell-derived
Description: Fully differentiated C3 h/10T1/2 adipocytes were cultured with 1 µM Rosi or vehicle for 1 h.
ID: 10.1621/hLnw2RmSWG
Mutational analysis of the peroxisome proliferator activated receptor-γ coactivator 1- β (PGC1β/Ppargc1b)-regulated transcriptome in mouse liver an... NURSA
Keywords: whole liver
Description: Liver and skeletal muscle were isolated from C5BL/6 wild type mice or mice expressing a mutant form of PGC1β/Ppargc1b lacking two out of the three LX...
ID: 10.1621/d4Kt4gB72O
Dose dependent analysis of the rosiglitazone (Rosi)-regulated liver and inguinal adipose tissue transcriptomes in the Leprdb null mutant mouse NURSA
Keywords: whole liver
Description: Liver or inguinal adipose tissue was collected from male BKS.Cg-m +/+ Leprdb/J mice treated with or without Rosi at a range of doses for 18 days. The...
ID: 10.1621/9IFwN8xkBn
Analysis of the 17β-estradiol (17βE2) dependent transcriptome in SUM44PE invasive lobular carcinoma breast cancer cell lines NURSA
Keywords: epithelium SUM44PE cells
Description: SUM44PE invasive lobular carcinoma breast cancer cell lines were treated with 1 nM 17βE2 or vehicle for 3 h and 24 h.
ID: 10.1621/6ugTmHZK5X
Transcriptomic analysis of progesterone (P4)-treated mouse ovary NURSA
Keywords: Female reproductive ovary whole
Description: Newborn Sprague-Dawley rat ovaries dissected from pups less than 8 h old, were cultured in the presence or absence of 1 µM P4 for 48 h.
ID: 10.1621/lbPzmF6Pwq
Analysis of the dexamethasone (Dex)- and testosterone (Test)-regulated transcriptomes in rat gastrocnemius muscle NURSA
Keywords: gastrocnemius whole
Description: Gastrocnemius muscle was isolated from male Wistar-Hannover rats treated with or without a combination of 0.7 mg/kg/d Dex and 28 mg/kg/d Test for 7 da...
ID: 10.1621/9MncYfbHNA
Analysis of the androgen receptor (AR) and dihydrotestosterone (DHT)-regulated transcriptomes in normal (LNCaP) and androgen-independent (LNCaP-abl) c... NURSA
Keywords: epithelium LNCaP cells
Description: Human LNCaP or LNCaP-abl prostate cancer cells were transfected with AR siRNA or scrambled control siRNA for 72 h. LNCaP-abl cells were also treated w...
ID: 10.1621/UhiFZHfzQW
Analysis of the Nur77/Nr4a1-regulated transcriptome in pyramidal neurons NURSA
Keywords: hippocampus pyramidal neurons
Description: After 10 days in culture, dissociated mouse hippocampal pyramidal neurons were infected with lentivirus expressing Nur77/Nr4a1 or GFP for 6 d.
ID: 10.1621/pDfF4bWOiY