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  1. Osmotic-Release Methylphenidate (OROS-MPH) for ADHD in Adolescents with Substance Use Disorders CTN

    Keywords: adolescent; adhd; oros-mph

    Description: Research shows a high prevalence of Attention Deficit Hyperactivity Disorder (ADHD) in adolescents with substance abuse disorders and indicates that t...

  2. A Feasibility Study of a Telephone Enhancement Procedure (TELE) to Improve Participation in Continuing Care Activities CTN

    Keywords:

    Description: Relapse rates are frequently high during the first few months after substance abuse treatment, often reversing many of the positive results of treatme...

  3. A Multicenter Safety Trial of Buprenorphine/Naloxone for the Treatment of Opiate Dependence CTN

    Keywords: phase 3; buprenorphine; naloxone; opiate

    Description: This 52-week study is designed to determine the efficacy and safety of a buprenorphine/naloxone sublingual tablet formulation as an office-based thera...

  4. HIV and HCV Risk Reduction Interventions in Drug Detoxification and Treatment Settings CTN

    Keywords: hepatitis c; hiv/aids

    Description: The connection between AIDS and drug injection is well established. Through June 2000, injection drug users accounted for more than a third of all cas...

  5. Screening, Motivational Assessment, Referral, and Treatment in Emergency Departments (SMART-ED) CTN

    Keywords: screening brief intervention and referral to treatment; emergency department

    Description: This was a randomized, controlled trial that enrolled 1285 participants who were identified with problematic substance use during an ED visit. Partici...

  6. Patient Feedback: A Performance Improvement Study in Outpatient Addiction Treatment CTN

    Keywords:

    Description: Although accrediting organizations, funding sources, and other agencies require community treatment providers to monitor performance, there are no stu...

  7. A Pilot Study of Osmotic-Release Methylphenidate in Initiating and Maintaining Abstinence in Smokers with ADHD CTN

    Keywords: adhd; oros-mph; smoking

    Description: Adult ADHD is a common and impairing neuro-psychiatric disorder, affecting approximating seven to eight millions adults in the United States. Substanc...

  8. A Multicenter Clinical Trial of Buprenorphine in Treatment of Opiate Dependence CTN

    Keywords: phase 3; buprenorphine; opiate

    Description: The primary purpose of this 16-week maintenance study is to determine the safety and effectiveness of 8 mg per day sublingual buprenorphine as compare...

  9. Safety Evaluation Of Cocaine Treatment Medication, Modafinil: Interactions With Intravenous Cocaine CTN

    Keywords: cocaine; interaction; modafinil; phase 1b

    Description: The primary objectives of this study are to determine: 1. The safety/tolerability of modafinil as a cocaine treatment medication in cocaine dependent ...

  10. MET to Improve Treatment Engagement and Outcome in Subjects Seeking Treatment for Substance Abuse CTN

    Keywords: motivational interviewing

    Description: Early dropout, partial attendance, and early relapse are common occurrences in most substance abuse treatment programs. Because the bulk of attrition ...

  11. Normal Human PBMC, Deep Sequencing, TCRB vs TCRG comparison. Adaptive Biotechnologies

    ID: doi:10.21417/B7SG6T

    Release Date: 07-14-2016

  12. The evolution of thymic lymphomas in p53 knockout mice Adaptive Biotechnologies

    ID: doi:10.21417/B7F59R

    Release Date: 07-14-2016

  13. CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human Skin Adaptive Biotechnologies

    ID: doi:10.21417/B76K56

    Release Date: 02-15-2017

  14. Next Generation Sequencing Reveals Restriction and Clonotypic Expansion of Regulatory T Cells in Juvenile Idiopathic Arthritis Adaptive Biotechnologies

    ID: doi:10.21417/B73W27

    Release Date: 07-14-2016

  15. De novo oligoclonal expansions of circulating plasmablasts in active and relapsing IgG4-related disease Adaptive Biotechnologies

    ID: doi:10.21417/B7RP4T

    Release Date: 07-14-2016

  16. TCRB Time Course Adaptive Biotechnologies

    ID: doi:10.21417/B7J01X

    Release Date: 07-14-2016

  17. Functional heterogeneity of human memory CD4+ T cell clones primed by pathogens or vaccines Adaptive Biotechnologies

    ID: doi:10.21417/B76P4V

    Release Date: 07-14-2016

  18. Impaired T cell function and skewed T cell receptor repertoire in untreated major depressive disorder Adaptive Biotechnologies

    ID: doi:10.21417/B7RG6H

    Release Date: 08-19-2016

  19. Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes Adaptive Biotechnologies

    ID: doi:10.21417/B73S3K

    Release Date: 12-08-2016

  20. Cocaine Use Reduction with Buprenorphine (CURB) CTN

    Keywords: naltrexone; cocaine; buprenorphine

    Description: This was a randomized, controlled trial that enrolled 302 cocaine-dependent participants who had either past-year opioid dependence or past-year opioi...


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