biomedical and healthCAre Data Discovery Index Ecosystem
biomedical and healthCAre Data Discovery Index Ecosystem
Clinical Evaluation of Hydrogels vs Silicone Hydrogel Contact Lenses ClinicalTrials.gov
ID: NCT01966770
Description: The aim of this fitting study is to evaluate the clinical performance of different hydrogel and silicone hydrogel contact lenses.
NCT01833130 ClinicalTrials.gov
Description: This study will evaluate the use of the Assessment of Chronic Migraine Impacts (ACM-I) Questionnaire in assessing the impact and benefit of trea...
A Pivotal Clinical Trial Examining the Safety and Effectiveness of the Adherus Dural Sealant System When Used as a Dural Sealant in Cranial Procedures ClinicalTrials.gov
ID: NCT01158378
Description: The purpose of the study is to demonstrate the safety and effectiveness of the Adherus Dural Sealant System when used as a dural sealant in conj...
A Randomized, Phase II Study of GW786034 (Pazopanib) in Stage D0 Relapsed Androgen Sensitive Prostate Cancer Following Limited GnRH Agonist Therapy ClinicalTrials.gov
ID: NCT00454571
Description: This randomized phase II trial is studying how well pazopanib hydrochloride works after leuprolide or goserelin in treating patients with relaps...
A Multi-center Study of the Safety and Efficacy of N-acetylcysteine in the Treatment of Acute Liver Failure in Pediatric Patients Not Caused by Acetam... ClinicalTrials.gov
ID: NCT00248625
Description: We have completed patient enrollment in the the double blind, randomized, placebo-controlled trial of intravenous (IV) N-acetylcysteine (NAC) vs...
Effects of Gabapentin Versus Placebo on Buprenorphine Detoxification of Opioid-dependent Individuals ClinicalTrials.gov
ID: NCT01262092
Description: This study involves inducting treatment seeking opioid dependent participants onto buprenorphine. Once the participant reaches a stable dose the...
Randomized Controlled Trial of DuraGen Plus® Adhesion Barrier Matrix to Minimize Adhesions Following Lumbar Discectomy ClinicalTrials.gov
ID: NCT00387829
Description: To evaluate the safety and effectiveness of DuraGen Plus® Adhesion Barrier Matrix as an adhesion barrier in spinal surgery to reduce the extent...
Varenicline Attenuates Some of the Subjective and Physiological Effects of Intravenous Nicotine in Humans. ClinicalTrials.gov
ID: NCT00606892
Description: To examine the effects of varenicline on the subjective, physiological and cognitive responses to intravenous nicotine. Varenicline is a partial...
A Phase 2, Multicenter, Open-Label Study to Investigate the Efficacy and Safety of Sofosbuvir/Ledipasvir Fixed-Dose Combination in Treatment-Naive and... ClinicalTrials.gov
ID: NCT02081079
Description: This study is to evaluate the efficacy, safety, and tolerability of ledipasvir/sofosbuvir (LDV/SOF) fixed-dose combination (FDC) in participants...
A Study of Therapy for Pediatric Relapsed or Refractory Acute Lymphoblastic Leukemia ClinicalTrials.gov
ID: NCT00186875
Description: The main purpose of this study is to find out how well participants with relapsed or refractory ALL respond to treatment with an etoposide- and ...
A Multicenter, Prospective, Observational, Non-Interventional Cohort Study Evaluating On-Treatment Predictors of Response in Subjects With HBeAg Posit... ClinicalTrials.gov
ID: NCT01011738
Description: This observational, non-interventional cohort study will evaluate predictors of response in patients with chronic hepatitis B receiving standard...
CARTO® 3 System and Real Time Intracardiac Ultrasound for Ablation of Drug Refractory Recurrent Symptomatic Paroxysmal AF: Acute Procedural Outcomes ... ClinicalTrials.gov
ID: NCT01716663
Description: This is a prospective, multicenter, non-randomized observational study of subjects 18 years and older undergoing RF ablation with drug refractor...
The Persistence of Oral Tolerance Induction to Peanut and Its Immunological Basis (ITN049AD) ClinicalTrials.gov
ID: NCT01366846
Description: ITN049AD (LEAP-On) Study is a continuation of the ITN032AD LEAP Study (NCT00329784). Peanut Allergy, a recognized public health concern, is a c...
Motivational Antidepressant Therapy for Hispanics ClinicalTrials.gov
ID: NCT00564278
Description: This study will evaluate the effectiveness of adding motivational interviewing to antidepressant treatment for major depressive disorder in Hisp...
An Open, Self-Controlled, Prospective Study of Concerta on Cognitive Functions, Efficacy and Tolerance in the Pediatric Patients With Attention Defici... ClinicalTrials.gov
ID: NCT01933880
Description: The purpose of this long term post-marketing study is to evaluate the effectiveness and safety of osmotic release oral system methylphenidate hy...
Double-blind Study in Paediatric Epileptic Subjects Aged From 5 to Less Than 8 Years to Compare the Subject Preference for ESL Suspension Formulation ... ClinicalTrials.gov
ID: NCT02021461
Description: The purpose of this study is to investigate the taste preference in children of 3 different flavours of the ESL oral suspension.
A Phase I, Open-Label, Non-Randomised, Multicentre Study to Assess the Effect of Rifampicin (a CYP3A4 Inducer) on the Pharmacokinetics of AZD9291 in P... ClinicalTrials.gov
ID: NCT02197247
Description: This is a Phase I, open-label, 2-part study in patients with a confirmed diagnosis of epidermal growth factor receptor (EGFR) mutation positive ...
Is the Combination of Screening Algorithms and Use of Hepatitis B Rapid Tests Useful in Optimizing the Screening and Prevention of Hepatitis B? ClinicalTrials.gov
ID: NCT01767597
Description: With over 280 000 chronic carriers, 2,500 new annual cases and 1,300 deaths each year, hepatitis B is currently a frequent and potentially sever...
Phase I/II Study of Dasatinib and Docetaxel in Metastatic Hormone Refractory Prostate Cancer ClinicalTrials.gov
ID: NCT00439270
Description: The purpose of this study is to find the recommended doses of dasatinib and docetaxel given in combination to men with metastatic hormone refrac...
A PHASE 3, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP STUDY TO EVALUATE THE EFFICACY AND SAFETY OF APREMILAST (CC-10004... ClinicalTrials.gov
ID: NCT01583374
Description: Apremilast is a new, orally available, small molecule drug that specifically inhibits phosphodiesterase 4 (PDE4), an enzyme that modulates infla...