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Title Date Released Description
Safety Evaluation Of Cocaine Treatment Medication, Modafinil: Interactions With Intravenous Cocaine 08-01-2016 The primary objectives of this study are to determine: 1. The safety/tolerability of modafinil as a ...
Cocaine-Metyrapone Interaction Study 08-01-2016 The primary objectives of this study are: 1. To demonstrate that a 750 mg dose of MRP is safe when u...
Assessment Of Potential Interactions Between Intravenous Methamphetamine And Oral Selegiline 08-01-2016 The primary objective of this study is to determine the safety of the selegiline concurrent with dme...
Assessment Of Potential Interactions Between Intravenous Cocaine And Tolcapone 08-01-2016 The primary objective of this study is to determine the safety of tolcapone treatment, compared to p...
Double-Blind, Placebo-Controlled Trial Of Ondansetron For The Treatment Of Cocaine Dependence 08-01-2016 The primary objective of this study is to conduct a preliminary assessment of the possible efficacy ...
A Multicenter Clinical Trial of Buprenorphine in Treatment of Opiate Dependence 09-02-2015 The primary purpose of this 16-week maintenance study is to determine the safety and effectiveness o...
Phase 2, Double-Blind, Placebo-Controlled Trial Of Modafinil For The Treatment Of Cocaine Dependence 09-02-2015 The primary objective of this study is to evaluate the efficacy of modafinil relative to placebo in ...
Phase 2, Double-Blind, Placebo-Controlled Trial Of Modafinil For Methamphetamine Dependence 09-02-2015 The primary objective of this study is to assess the efficacy of modafinil in increasing the number ...
A Multicenter Safety Trial of Buprenorphine/Naloxone for the Treatment of Opiate Dependence 09-02-2015 To determine if the 4:1 buprenorphine/naloxone combination tablet can be effectively used to treat p...
Phase 2, Double-Blind, Placebo-Controlled Trial Of Topiramate For The Treatment Of Methamphetamine Dependence 09-02-2015 The primary efficacy objective of this study is to determine if topiramate relative to placebo reduc...
Cocaine Use Reduction with Buprenorphine (CURB) 04-24-2015 This was a randomized, controlled trial that enrolled 302 cocaine-dependent participants who had eit...
Stimulant Reduction Intervention using Dosed Exercise (STRIDE) 04-24-2015 This was a randomized, controlled trial that enrolled 302 participants diagnosed with stimulant abus...
A Multicenter Safety Trial of Buprenorphine/Naloxone for the Treatment of Opiate Dependence 12-04-2014 This 52-week study is designed to determine the efficacy and safety of a buprenorphine/naloxone subl...
A Multicenter Efficacy/Safety Trial of Buprenorphine/Naloxone for the Treatment of Opiate Dependence 12-04-2014 This 52-week study is designed to determine the efficacy and safety of a buprenorphine/naloxone subl...
Phase 2, Double-Blind, Placebo-Controlled Trial Of Reserpine For The Treatment Of Cocaine Dependence 12-04-2014 The primary objective of this study is to assess the efficacy of reserpine in reducing cocaine use i...
Phase 2, Double-Blind, Placebo-Controlled Trial Of Bupropion For Methamphetamine Dependence 12-04-2014 The primary objective of this study is to assess the efficacy of bupropion in reducing methamphetami...
Double-Blind, Placebo-Controlled Assessment Of Potential Interactions Between Intravenous Methamphetamine And Osmotic-Release Methylphenidate (Oros-Mph) 12-04-2014 The primary objective of this study is to determine the safety of the OROS-MPH concurrent with i.v. ...
Screening, Motivational Assessment, Referral, and Treatment in Emergency Departments (SMART-ED) 09-02-2014 This was a randomized, controlled trial that enrolled 1285 participants who were identified with pro...
Long-Term Follow-Up to CTN-0030 (A Two-Phase Randomized Controlled Clinical Trial of Buprenorphine/Naloxone Treatment Plus Individual Drug Counseling for Opioid Analgesic Dependence) 08-22-2014 This was an ancillary study to CTN-0030, a two-phase randomized controlled clinical trial of bupreno...
Project Aware: HIV Rapid Testing & Counseling in STD Clinics in the U.S. – an Adaptation of CTN-0032 07-03-2014 This was a randomized, controlled trial in which 5012 participants seeking medical or health service...