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Title Description Data Acquisition Date Released
Comparative analysis of the amorfrutin A and rosiglitazone (Rosi)-dependent hepatic transcriptomes in a mouse model of diet-induced obesity Male C57BL/6 mice at 6 weeks of age were fed a HFD (60% of calories as fat) for 12 weeks to induce o... Transcriptomic 11-30-2016
Analysis of the estrogen-related receptor β (ERRβ/ESRRB) and DY131-regulated transcriptome in human DU145 prostate cancer cells Human DU145 prostate cancer cells stably transfected with an ERRβ/ESRRB expression vector or an emp... Transcriptomic 01-18-2017
Chronic time course and dose-dependence analysis of the clofibrate (Clofib)-regulated transcriptome in rat liver Livers were isolated from rats treated for 4 - 29 d with or without 30 - 300 mg/kg bw/d Clofib. Transcriptomic 07-12-2016
Analysis of the 17β-estradiol (17βE2)-regulated transcriptome in rat trigeminal ganglia Cultured trigeminal ganglia from 8 week old random cycling female rats were 17βE2-deprived then tre... Transcriptomic 03-28-2015
Comparative analysis of the 17β-estradiol (17βE2)-, genistein (Gen)-, and phytoestrogen (S-equol [Sequol] and liquiritigenin [Liquir])-regulated, estrogen receptor-β (ERβ/ESR2)-dependent transcriptomes in MCF-7 breast cancer cells. Human MCF-7 breast cancer cells were infected for 72 h with (i) control adenovirus expressing β-gal... Transcriptomic 01-13-2017
Analysis of the Ssfa2-dependent transcriptome in mouse liver Liver was isolated from 32 week old C57BL6/J male Ssfa2 KO and WT mice fed a normal chow diet. Transcriptomic 03-20-2017
Analysis of the Bromo Adjacent Homology Domain Containing 1 (Bahd1)-dependent transcriptome in mouse E16.5 placenta and liver Placenta and liver tissue was isolated at embryonic day 16.5 from male and female Bahd1 knockout and... Transcriptomic 03-27-2017
Tissue-specific expression patterns of nuclear receptor coregulators C57/Bl6J and 129x1/SvJ male or female mice (n = 6) at 8-9 weeks of age from each strain were sacrifi... Q-PCR 03-28-2015
Acute time course and dose-dependence analysis of the clofibrate (Clofib)-regulated transcriptome in rat liver Livers were isolated from rats treated for 3 - 24 h with or without 30 mg - 300 mg/kg bw/d Clofib. Transcriptomic 05-06-2016
Analysis of the GW501516 (GW1516)-regulated transcriptome in primary human macrophages expressing constitutively active AMPK Primary human macrophages transduced with constitutively active (T172A) AMPK α1 variant were treate... Transcriptomic 05-05-2016
Analysis of the dihydrotestosterone (DHT)-regulated transcriptome in human LNCaP-C4-2B prostate cancer cells Human LNCaP-C4-2B prostate cancer cells were treated with for 16 h with or without 10 nM DHT. Transcriptomic 07-15-2016
Time course and dose dependence analysis of the bisphenol A (BPA)-regulated transcriptome in Ishikawa cells Human Ishikawa endometrial carcinoma cells were treated with or without 1 nM, 100 nM, 10 µM or 100 ... Transcriptomic 03-28-2015
Time course transcriptomic analysis of rosiglitazone (Rosi)-treated C3H/10T1/2 cells Fully differentiated C3 h/10T1/2 adipocytes were cultured with 1 µM Rosi or vehicle for 1 h. Transcriptomic 03-28-2015
Mutational analysis of the peroxisome proliferator activated receptor-γ coactivator 1- β (PGC1β/Ppargc1b)-regulated transcriptome in mouse liver and skeletal muscle Liver and skeletal muscle were isolated from C5BL/6 wild type mice or mice expressing a mutant form ... Transcriptomic 03-28-2015
Dose dependent analysis of the rosiglitazone (Rosi)-regulated liver and inguinal adipose tissue transcriptomes in the Leprdb null mutant mouse Liver or inguinal adipose tissue was collected from male BKS.Cg-m +/+ Leprdb/J mice treated with or ... Transcriptomic 03-28-2015
Analysis of the 17β-estradiol (17βE2) dependent transcriptome in SUM44PE invasive lobular carcinoma breast cancer cell lines SUM44PE invasive lobular carcinoma breast cancer cell lines were treated with 1 nM 17βE2 or vehicle... Transcriptomic 03-28-2015
Transcriptomic analysis of progesterone (P4)-treated mouse ovary Newborn Sprague-Dawley rat ovaries dissected from pups less than 8 h old, were cultured in the prese... Transcriptomic 03-28-2015
Analysis of the dexamethasone (Dex)- and testosterone (Test)-regulated transcriptomes in rat gastrocnemius muscle Gastrocnemius muscle was isolated from male Wistar-Hannover rats treated with or without a combinati... Transcriptomic 03-28-2015
Analysis of the androgen receptor (AR) and dihydrotestosterone (DHT)-regulated transcriptomes in normal (LNCaP) and androgen-independent (LNCaP-abl) cells Human LNCaP or LNCaP-abl prostate cancer cells were transfected with AR siRNA or scrambled control s... Transcriptomic 03-28-2015
Analysis of the Nur77/Nr4a1-regulated transcriptome in pyramidal neurons After 10 days in culture, dissociated mouse hippocampal pyramidal neurons were infected with lentivi... Transcriptomic 05-06-2016
Analysis of the GW4604-dependent transcriptome in the intestine of the Cyp27a1 null mutant mouse 3-4 month Cyp27a1 knockout mice were treated with or without two doses of 100 mg/kg body weight GW40... Transcriptomic 03-28-2015
Dose-dependent transcriptomic analysis of the diethylhexylphthalate (DEHP)-treated rat neonatal cardiomyocytes Rat neonatal cardiomyocytes isolated from 2-day-old Sprague-Dawley rat pups were treated with or wit... Transcriptomic 03-28-2015
Comparative analysis of peroxisome proliferator-activated receptor-γ (PPARγ/Pparg)- and GW7845-regulated transcriptomes in rat pancreatic islets Rat pancreatic islets isolated from male Wistar rats were transduced with PPARγ/Pparg adenovirus or... Transcriptomic 03-28-2015
Analysis of the dihydrotestosterone (DHT)- and RTI 6413-018-dependent transcriptomes in LNCaP prostate cancer cells Human LNCaP prostate cancer cells were treated with 10 nM DHT or 100 nM RTI 6413-018 for 6-24 h. Transcriptomic 03-28-2015
Analysis of the p300/CBP interacting protein (pCIP/Ncoa3) dependent transcriptome in mouse embryonic stem cells Mouse E14 embryonic stem cells were transfected with two pCIP siRNAs or pooled non-specific siRNAs. Transcriptomic 03-28-2015
Analysis of the thyroid hormone receptor-α (TRα/THRA) and TRβ/THRB-regulated transcriptomes in human HepG2 hepatocellular carcinoma cells Human HepG2 hepatocellular carcinoma cells stably expressing TRα/THRA, TRβ/THRB, or empty vector w... Transcriptomic 03-28-2015
Analysis of the all-trans retinoic acid (ATRA)-regulated, retinoid X receptor-α (RXRα/Rxra)-dependent transcriptome in mouse liver Liver was isolated from male C57BL/6 RXRα/Rxra knockout and wild-type (WT) mice fed a 150 mg/kg ATR... Transcriptomic 03-28-2015
Time course transcriptomic analysis of 17β-estradiol (17βE2)-treated MCF-7 cells Human MCF-7 breast carcinoma cells were treated with or without 100 nM 17βE2 for 10 min, 40 min or ... Transcriptomic 03-28-2015
Analysis of the hepatocyte nuclear factor 4-α variant 2 (HNF4α/HNF4A-2)-dependent transcriptome in rat pancreatic beta cells Rat INS-1 pancreatic beta-cells were stably transfected with a vector encoding tetracycline inducibl... Transcriptomic 03-28-2015
Analysis of the 17β-estradiol (17βE2)-dependent transcriptome in human vagina Vaginal samples were retrieved from women treated with or without 0.05 mg/day 17βE2 for 3 months. Transcriptomic 03-28-2015
Analysis of the Am580 and rosiglitazone (Rosi) dependent transcriptomes in human monocyte-derived dendritic cells Human monocyte-derived dendritic cells were treated with 100 nM Am580, 2.5 µM Rosi, and 1 µM AGN19... Transcriptomic 03-28-2015
Analysis of the MEK1/2-regulated transcriptome in R5020-treated human T47D cells Human T47D breast cancer cells were treated with or without a combination of (1) vehicle or (2) 10 ... Transcriptomic 03-28-2015
Analysis of the 1,25-dihydroxyvitamin D3 (125DVD3)-dependent transcriptome in human primary bronchial smooth muscle cells Human primary bronchial smooth muscle cells were treated with or without 100 nM 125DVD3 for 24 h. Transcriptomic 03-28-2015
Transcriptomic analysis of WY 14,643 and thyroid hormone receptor-β (TRβ/Thrb) Δ337T cross-talk in mouse heart 4-6 month old male wild-type mice or mice with cardiomyocyte specific expression of human TRβ/Thrb1... Transcriptomic 03-28-2015
Timecourse analysis of the 17β-estradiol (17βE2) dependent transcriptome in T47D, MCF-7 and BT-474 breast cancer cell lines Human T47D, MCF-7, and BT-474 breast cancer cells were treated with 10 nM 17βE2 or vehicle for 1-24... Transcriptomic 03-28-2015
Time course analysis of the all-trans retinoic acid (ATRA)-regulated transcriptome in multipotent P19-derived A404 cells Multiprotein A404 cells expressing puromycin-N-acetyltransferase under the smooth muscle α-actin pr... Transcriptomic 03-28-2015
Transcriptomic analysis of (1) wild type peroxisome prolferator activated receptor-γ coactivator 1 (PGC1α/PPARGC1); (2) estrogen receptor related receptor-α (ERRα/ESRRA)-disrupted PGC1α; and (3) ERRα-specific PGC1αPPARGC1 in HepG2 cells Human HepG2 liver cancer cells were subjected to adenoviral infection with empty vector or vectors e... Transcriptomic 03-28-2015
Analysis of the estrogen receptor-α (ERα/ESR1)-dependent transcriptome in MCF-7 breast cancer cells Human MCF-7 breast cancer cells were transfected with an ERα/ESR1 shRNA plasmid. Transcriptomic 03-28-2015
Analysis of the 17β-estradiol (17βE2)-regulated transcriptome in mouse hippocampus Four month old ovariectomized female C57BL/6 mice were treated with 0.2mg/kg 17βE2 for 1 h prior to... Transcriptomic 03-28-2015
Time course analysis of the Tamoxifen (Tam)-regulated transcriptome in mouse uterus Ovariectomized female C57BL/6 mice were treated with and without 100 µg/kg body weight Tam for 2 h ... Transcriptomic 03-28-2015
Analysis of the benzo[a]pyrene (B[a]P)-dependent transcriptome in primary hepatocytes from DNA repair-deficient mice Primary hepatocytes from male wild type or DNA repair-deficient Xpa-/- TP53+/- C57BL/6 mice were cul... Transcriptomic 08-05-2015
Age-dependence and time-course analysis of the 17β-estradiol (17βE2)-regulated transcriptome in mouse hippocampus Young (4 months), middle aged (12 months) or aged (18 months) ovariectomized female C57BL/6 mice wer... Transcriptomic 03-28-2015
Comparative analysis of hepatotoxicant transcriptomes in murine liver Liver was isolated from male and female 7 week old B6C3F1/Crl mice treated for 6 - 72 h with hepatot... Transcriptomic 12-03-2016
Chronic time course and dose-dependence analysis of the chlorpromazine (Chlorprom)-regulated transcriptome in rat liver Livers were isolated from rats treated for 4 - 29 d with or without 4.5 - 45 mg/kg bw/d Chlorprom. Transcriptomic 05-04-2016
Analysis of the 17β-estradiol (17βE2)-dependent hepatic transcriptome in the Lep null mutant mouse 12 week old female leptin (Lep) null mutant mice (Lep KO) were injected with or without 100 µg/kg b... Transcriptomic 03-28-2015
Dose analysis of the fenofibrate (Feno)-regulated transcriptome in rat liver 7 week old F344/N Slc rats were adminstered (1) ) 0 ppm; (2) 3,000 ppm (8.3 µM); or (3) 6,000 ppm (... Transcriptomic 03-28-2015
Analysis of the estrogen receptor-related receptor-α (ERRα/Esrra)-regulated transcriptome in mouse kidney Kidneys were isolated from ERRα/Esrra knockout and wild-type male 2-3 month old mice. Transcriptomic 03-28-2015
Analysis of the 17β-estradiol (17βE2)- and Tamoxifen (Tam)- regulated transcriptomes in Hs587T cells stably expressing estrogen receptor-α (ERα/ESR1) or ERβ/ESR2 Human Hs578T breast cancer cells were stably transfected with tetracycline-inducible vectors encodin... Transcriptomic 03-28-2015
Transcriptomic profiling of GW3965-treated differentiated human adipocytes In vitro-differentiated human adipocytes were treated with and without GW3965 for 24 h. Transcriptomic 03-28-2015
Analysis of the 17β-estradiol (17βE2)-regulated transcriptome in rat hippocampus Ovariectomized female Wistar rats were treated with and without 10 µg/kg body weight 17βE2 for 8 h... Transcriptomic 03-28-2015