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Dataset Title Keywords Date Released Description
Natural Variation in Fish Transcriptomes: Comparative Analysis of the Fathead Minnow (Pimephales promelas) and Zebrafish (Danio rerio) unknown experiment type
transcription profiling by array
08-19-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Dazl is required for TET-mediated reprogramming to a naïve pluripotent state (I) transcription profiling by array 08-19-2015 Embryonic stem cell (ESC) cultures display a heterogeneous gene expression profile, ranging from a p...
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells [time-course microarray] transcription profiling by array 08-19-2015 Transcription factor-mediated reprogramming is a powerful method to study cell fate changes. In this...
E. histolytica and E. invadens RNA-seq of non coding RNA 08-19-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Expression data from primary human mammary fibroblasts purified from disease-free women of low and high mammographic density transcription profiling by array 08-18-2015 Although high mammographic density (MD) is considered one of the strongest risk factors for invasive...
Gene expression profile of hemocytes from Manila clam (Venerupis philippinarum) after a Perkinsus olseni challenge using an immune-enriched oligo-microarray transcription profiling by array 08-19-2015 Parasites of the genus Perkinsus spp. cause high mortalities and economic losses to the most noticea...
A DNA Hypomethylation Signature Predicts Novel Anti-Tumor Activity of LSD1 Inhibitors in SCLC (ChIP-Seq) ChIP-seq 08-19-2015 Epigenetic dysregulation has emerged as an important mechanism in cancer. Alterations in epigenetic...
Tbx3 controls Dppa3 levels to regulate exit from pluripotency towards mesodermal lineage RNA-seq of coding RNA
ChIP-seq
08-19-2015 Tbx3, a member of the T-box family, plays important roles in development, stem cells, nuclear reprog...
Aberrant ERK signaling causes resistance to EGFR kinase inhibitors transcription profiling by array 08-18-2015 The clinical efficacy of EGFR kinase inhibitors is limited by the development of drug resistance. Th...
Gene expression profiling of human Ewing sarcoma cells after knockdown of EGR2 or EWSR1-FLI1. transcription profiling by array 08-19-2015 To get insight in the functional role of EGR2 for Ewing sarcoma, we performed a transcriptional prof...
Effect of type 2 diabetes on transcriptional signatures during exercise and recovery transcription profiling by array 08-19-2015 We performed gene expression microarray analysis of skeletal muscle biopsies from normal glucose tol...
Expression data analyzed with LPIA in A549 lung carcinoma cells treated with geldanamycin. transcription profiling by array 08-11-2015 The statsitcal model, latent pathway identification analysis (LPIA), was implemented for the analysi...
Exon expression for NCI Sarcoma cell line panel transcription profiling by array 08-19-2015 Characterization of 68 cell lines derived from human sarcoma and 5 normal counterpart cells, includ...
System-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity transcription profiling by array 08-19-2015 We’ve undertaken a genome-wide approach to identify and test genes in fibroblasts that are both in...
Conversion of MyoD to a neurogenic factor: binding site specificity determines lineage [RNA-seq] RNA-seq of coding RNA 08-19-2015 MyoD and NeuroD2 are master regulators of myogenesis and neurogenesis and bind to a "shared&quo...
Small RNAs during E. histolytica stress response RNA-seq of non coding RNA 08-19-2015 We analyzed ~27nt small RNAs from Entamoeba histolytica trophozoites in basal conditions and after h...
Genome-wide expression of the leukemic cells with different sensitivity to AraC transcription profiling by array 08-19-2015 To examine the molecular alterations in cells with different sensitivity, genome-wide expression of ...
CGH analyses for the Chinese indigenous pig breeds and commercial pig breeds [Agilent] comparative genomic hybridization by array 08-19-2015 Since CNVs play a vital role in genomic studies, it is an imperative need to develop a comprehensive...
Germline duplication of ATG2B and GSKIP predisposes to familial essential thrombocythemia rapidly progressing to acute leukemia comparative genomic hybridization by array 08-19-2015 No major predisposing gene for familial myeloproliferative neoplasms (MPN) has been identified. Here...
Integrative ‘omic analysis of experimental bacteremia identifies a metabolic signature that distinguishes human sepsis from SIRS RNA-seq of coding RNA 08-19-2015 Rationale: Sepsis is a leading cause of morbidity and mortality; early diagnosis and prediction of p...
Assessment of MEK-ERK pathway targeting by BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias [Patient samples] transcription profiling by array 08-19-2015 Multiple myeloma (MM) is a malignant disorder characterized by the clonal proliferation of plasma ce...
Assessment of MEK-ERK pathway targeting by BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias [U266 human myeloma cell line] transcription profiling by array 08-19-2015 Multiple myeloma (MM) is a malignant disorder characterized by the clonal proliferation of plasma ce...
Gene expression profile in MCF7 breast cancer cells after siRNA knock down of estrogen receptor alpha (ESR1) transcription profiling by array 08-18-2015 Affymetrix microarray data was generated from MCF7 breast cancer cells treated in vitro with siRNAs ...
CD8 in vitro CD2-costimulation transcription profiling by array 08-12-2015 Purified primary human CD8 T cells were stimulated in vitro in parallel using a magnetic bead conjug...
Hepatic miRNA profiles and thyroid hormone homeostasis in rats exposed to dietary potassium perfluorooctanesulfonate (PFOS) [miRNA] transcription profiling by array 08-19-2015 Perfluorooctanesulfonate (PFOS) has been widely used in a variety of industrial and commercial appli...
Fitness of natural Saccharomyces cerevisiae strains [Expression] transcription profiling by array 08-19-2015 To characterize the ecological interactions among S. cerevisiae strains coming from the same geograp...
Lung adenocarcinoma metastasis is suppressed by the alveolar lineage transcription factors GATA6 and HOPX. RNA-seq of coding RNA 08-18-2015 Molecular programs that mediate normal cell differentiation are required for oncogenesis and tumor c...
Micro-array analysis of the anterior vaginal wall from premenopausal patients with Pelvic Organ Prolapse (POP) transcription profiling by array 08-19-2015 Pelvic organ prolapse (POP) is a common multifactorial disease in a heterogeneous population of wome...
Expression data from MDA-MB-231 cell line treated with Zoledronate, or Fluvastatin, or mock-treated control cells. transcription profiling by array 08-17-2015 Statins and bisphosponates (BPs) are two distinct classes of isoprenoid pathway inhibitors targeting...
Transcriptional profiling of clinically relevant SERMs and SERM/estradiol complexes in a cellular model of breast cancer transcription profiling by array 08-17-2015 In this study, we have utilized microarray analysis to directly compare a subset of structurally dis...
Expression profile of A1-2 cells treated with 100 nM Dexamethasone or ethanol vehicle for 8h transcription profiling by array 08-12-2015 A1-2 cells treated with 100 nM Dexamethasone or ethanol vehicle for 8h. The ability of steroid hormo...
Transcription profiling by 3'-end sequencing of whole blood from pancreatic ductal adenocarcinoma (PDAC) patients and healthy controls for PDAC diagnosis RNA-seq of coding RNA 08-14-2015 We sequenced the transcriptomes using massive analysis of cDNA ends (MACE) of whole blood samples fr...
MeCP2 binds to mCH as neurons mature, influencing transcription and onset of Rett syndrome [Mnase-Seq] ChIP-seq 08-19-2015 The postnatal neurodevelopmental disorder Rett syndrome (RTT) is caused by mutations in the gene enc...
Epigenomic Evolution of Diffuse Large B-cell Relapse methylation profiling by high throughput sequencing 08-19-2015 Here we characterize an association between disease progression and DNA methylation in Diffuse Large...
LEF-1 and TCF-1 orchestrate T follicular helper (Tfh) cell differentiation by regulating Tfh differentiation circuits upstream of Bcl6 RNA-seq of coding RNA 08-19-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Microarray analysis of gene expression changes in human A549 lung cancer cells upon siRNA knockdown of FAM60A and SDS3 transcription profiling by array 08-18-2015 The Sin3 histone deacetylase (HDAC) complex is a 1.2 MDa chromatin modifying complex that can repres...
Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of Trophoblast Stem Cells RNA-seq of coding RNA
ChIP-seq
08-18-2015 Derivation and maintenance of TS cells depends on the presence of Fgf signalling. Numerous gene knoc...
Expression data from breast cancer tumor-initiating cells transcription profiling by array 08-14-2015 We have generated tumorigenic (S2N) and non-tumorigenic (S2), normal-like to basal-like breast cance...
Expression data from knockdown of G9a in MDA-MB231 cells transcription profiling by array 08-17-2015 G9a is an H3K9m2 methyltransferase, which is critical in controlling gene suppression and DNA methyl...
High-throughput sequencing of mouse liver transcriptome in Clock mutant animals RNA-seq of coding RNA 08-19-2015 Circadian profile of polyA RNA by RNA-Seq, collected from ClockΔ19 mouse liver at CT22, CT28, CT34,...
RNA-Seq profiling of single bovine oocyte transcript abundance and its modulation by cytoplasmic polyadenylation RNA-seq of coding RNA 08-19-2015 Polyadenylated RNA from individual germinal vesicle and metaphase II ooyctes was amplified and proce...
Molecular anatomy of palate development RNA-seq of coding RNA 08-19-2015 Background: The FACEBASE consortium was established in part to create a central resource for craniof...
Transciptional response to acute thermal stress in Chinook salmon RNA-seq of coding RNA 08-19-2015 Thermal stress is a serious and growing challenge facing Chinook salmon (Oncorhynchus tshawytscha) l...
Interactions of melanoma cells with distal keratinocytes trigger metastasis via Notch signaling inhibition of MITF RNA-seq of non coding RNA 08-19-2015 The most critical stage in initiation of melanoma metastasis is the radial to vertical growth transi...
A Myc transcriptional program that is independent of EMT drives a poor prognosis tumor-propagating phenotype in HER2+ breast cancer transcription profiling by array 08-19-2015 The HER2 (ERBB2) and MYC genes are commonly amplified genes in breast cancer, yet little is known ab...
Gene expression alterations in human colon cancer xenograft treated with anti-VEGF antibody transcription profiling by array 08-18-2015 Recent randomized clinical trial revealed the additional effect of bevacizumab, a humanized monoclon...
Molecular changes induced in melanoma cells by stromal cells and anti-BRAF therapy. transcription profiling by array 08-19-2015 Tumor-associated stromal cells can enable cancer cells to become insensitive to therapy. They can pr...
Expression profile of U373 cells over-expressing DTX1 and cells expressing a dominant negative form of MAML1 transcription profiling by array 08-10-2015 Glioblastoma multiforme (GBM) is the most malignant and most common tumor of the central nervous sys...
Networking of differentially expressed genes in human MCF7 breast cancer cells resistant to methotrexate transcription profiling by array 08-06-2015 A summary of the work associated to these microarrays is the following: The need for an integrated ...
Expression data from human skin exposed to solar-simulated radiation with or without sunscreen transcription profiling by array 08-10-2015 Despite widespread use of sunscreens that minimize erythema by blocking ultraviolet B (UVB) radiatio...
A Randomized, Placebo-Controlled Study to Evaluate SRT2104, a Selective SIRT1 Activator, in Patients with Moderate to Severe Psoriasis transcription profiling by array 08-07-2015 Activation of Sirtuin (silent mating type information regulation 2 homolog) 1, or SIRT1, is an unexp...
Networking of differentially expressed genes in human K562 erythtoblastic leukemia cells resistant to methotrexate transcription profiling by array 08-06-2015 A summary of the work associated to these microarrays is the following: The need for an integrated ...
Transcriptional profiling of A549 lung adenocarcinoma cells in response to overexpression or supression of X-ray responsive microRNAs to identify regulated target mRNA transcription profiling by array 08-12-2015 'MicroRNA (miRNA) is a type of non-coding RNA that regulates the expression of its target genes by i...
Expression data of MCF7/ADR cells treated with MC70, an ABC transporters inhibitor transcription profiling by array 08-12-2015 A major limitation in the cancer treatment is the ability of cancer cells to become resistant to che...
Profiling of p53-responsive genes in human breast cancer cells harboring endogenous ts-p53 E285K transcription profiling by array 08-17-2015 The ts-p53 E285K protein is a rare p53 mutant with temperature-sensitive (ts) loss of function chara...
Expression data from cultured human lung tissue-derived fibroblasts and human vascular adventitial fibroblasts transcription profiling by array 08-12-2015 In order to find the difference between human lung tissue-derived fibroblasts and human vascular adv...
Expression profile of MDA-MB-231 and MCF7 cells stably transfected with GFP-Numb4, GFP-Numb5, GFP-Numb6 transcription profiling by array 08-12-2015 Numb has 4 known variants and we are reporting two novel Numb variants, Numb5 and Numb6 in this stud...
Expression data from MCF7 cells treated with Neuregulin (NRG) at different times transcription profiling by array 08-05-2015 To gain insights into the mechanism responsible for the protumorigenic actions of NRG we performed g...
Expression data from MCF-7 cells stimulated by Estrogen or IGF-I transcription profiling by array 08-11-2015 Although estrogen receptor (ER) and insulin-like growth factor (IGF) signaling are important for nor...
Networking of differentially expressed genes in human MDA-MB-468 breast cancer cells resistant to methotrexate transcription profiling by array 08-06-2015 A summary of the work associated to these microarrays is the following: The need for an integrated ...
Candidate genes for the recurrence of glioblastoma multiforme identified by microarray transcription profiling by array 08-06-2015 Background: Glioblastoma multiforme (GBM) is the most aggressive and most lethal primary malignant b...
Genome-Wide Expression Profiling of human tumor-infiltrating microglia/macrophages stimulated by Toll-like receptor 3 agonist poly (I:C) transcription profiling by array 08-10-2015 Microglia isolated from glioma patients gain anti-tumor activities upon poly (I:C) stimulation. Expr...
Microarray characterization of gene expression changes in blood during acute ethanol exposure transcription profiling by array 08-07-2015 As part of the civil aviation safety program to define the adverse effects of ethanol on flying perf...
Defining the Genomic Signature of the Parous Breast transcription profiling by array 08-11-2015 It is widely accepted that a woman’s lifetime risk of developing breast cancer at menopause is red...
Mutant p53 Disrupts Mammary Acinar Morphogenesis via the Mevalonate Pathway transcription profiling by array 08-13-2015 p53 is a frequent target for mutation in human tumors and previous studies have revealed that these ...
SIN3A-regulated LIF-responsive genes in MCF7 cells transcription profiling by array 08-17-2015 Tyrosine phosphorylation is a hallmark for activation of Signal Transducer and Activator of Transcri...
Transcription profiling by array of human MCF10A cells over-expressing HRas or MEK1 transcription profiling by array 08-12-2015 MCF10A cells were then transfected with MEK1(S217S221), HRAS(G12V), and null control vectors; Cells ...
Claudin 1 mediates TNF alpha-induced gene expression and cell migration in human lung carcinoma cells transcription profiling by array 08-14-2015 Epithelial-mesenchymal transition (EMT) is an important mechanism in carcinogenesis. To determine th...
Innate lymphoid cell development requires TOX-dependent generation of a common ILC progenitor RNA-seq of coding RNA 08-05-2015 Subtypes of innate lymphoid cells (ILC), defined by effector function and transcription factor expr...
Expression data from breast tumors and reduction mammoplasty explants transcription profiling by array 08-10-2015 Breast tumorigenesis involves modulation of gene expression. We used microarrays to detail the globa...
DNA Methylation Profiling of Glioblastoma: Impact on Gene Expression and Clinical Outcome (Agilent Expression Study) transcription profiling by array 08-07-2015 Genome-scale measurements of DNA methylation levels are necessary to decipher the epigenetic events ...
Gene expression signatures of symptomatic respiratory viral infection in adults transcription profiling by array 08-10-2015 Diagnosis of acute respiratory viral infection is currently based on clinical symptoms and pathogen ...
gene expression profiling of three type of grade II gliomas transcription profiling by array 08-07-2015 In this study we performed gene expression profiling of 14 cases of grade II gliomas. The results of...
S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells [HG-U133_Plus_2] transcription profiling by array 08-06-2015 We and others have shown that S100P is highly upregulated during the progression of pancreatic cance...
Transcription profiling by array of human glioblastoma mulitforme tumors after dendritic cell vaccination transcription profiling by array 08-05-2015 Human Glioblastoma Multiforme tumors taken before dendritic cell vaccination, the recurrent tumors t...
Expression data from human PBMC induced by mixed Congeners of PCBs at Human equivalence transcription profiling by array 08-05-2015 Exposure to Polychlorobiphenyls (PCBs) is known to cause serious health effects in human but the gen...
Transcription profiling by array of human cancer cell lines resistant to methotrexate transcription profiling by array 08-06-2015 This SuperSeries is composed of the following subset Series:; GSE11440: Role of Caveolin 1, E-Cadher...
Characterization of protoporphytin IX effects on X-ray irradiation in Hela cells in vitro transcription profiling by array 08-05-2015 Hela cells were used to evaluate the protoporphytin IX (PpIX) effects on X-ray irradiation. Treatmen...
Resveratrol induces downregulation of DNA repair genes in MCF7 human breast cancer cells. transcription profiling by array 08-10-2015 Breast cancer is a worlwide health problem. One of the factors involved in carcinogenesis is diet. S...
Expression data from MDA-MB-231 cells treated with vehicle or YW3-56 transcription profiling by array 08-05-2015 PAD4 is overexpressed in many cancer cells. We developed PAD inhibitors that efficiently inhibit the...
mRNA expression data from BCR-ABL, MYC and CD22DE12 transgenic mouse models transcription profiling by array 06-26-2015 Leukemic splenocytes from these commercial transgenic mice that developed fatal leukemia with massiv...
caArray_hanas-00078: Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis transcription profiling by array 06-26-2015 Astrocytomas are heterogeneous intracranial glial neoplasms ranging from the highly aggressive malig...
Human Calu-3 cell transcriptome response to human interferon α [miRNA] transcription profiling by array 06-26-2015 The purpose is to obtain samples for mRNA and miRNA analysis with and without interferon α treatmen...
Large scale analysis of apple mealiness within IM apple progeny transcription profiling by array 06-26-2015 Based on sensorial analysis over 4 years, 6 apple genotypes with contrasted fruit texture (mealy or ...
Comprehensive genomic analysis of relapse neuroblastoma [arrayCGH] comparative genomic hybridization by array 06-27-2015 Relapse neuroblastoma were characterized by sequencing, gene expression, arrayCGH and genome-wide me...
Whole blood transcriptome analysis of Mycoplasma mycoides subsp, mycoides-infected cattle confirms immunosuppression but does not reflect local inflammation transcription profiling by array 06-27-2015 In order to assess the use of whole blood transcriptome analysis to study cattle-Mmm interactions, w...
Therapeutic antiviral T cells noncytopathically clear persistently infected microglia after conversion into antigen-presenting cells transcription profiling by array 06-27-2015 Several viruses can infect the mammalian nervous system and induce neurological dysfunction. Adoptiv...
Varicella-Zoster Virus (VZV) quiescent and productive infection of neurons derived from human embryonic stem cells RNA-seq of coding RNA 06-22-2015 quiescent and productive infection of varicella zoster virus in human embryonic stem stem cell-deriv...
Identification of neurexophilin 3 as a novel maturation factor for induced pluripotent stem cell-derived dopaminergic neuron progenitors transcription profiling by array 06-21-2015 To develop more potent cell transplantation therapy for neurodegenerative disorder such as Parkinson...
A simple method for generating high-resolution maps of genome wide protein binding ChIP-seq 06-21-2015 Chromatin immunoprecipitation (ChIP) and its derivatives are the main techniques used to determine t...
Gene based expression changes in glioblastoma cells after downregulation of MPS1 kinase transcription profiling by array 06-21-2015 Gene expression changes were analyzed in U251 GBM cells after downregulation of MPS1 by RNA interfer...
Human Bronchoalveolar Lavage Cells Gene Expression After Exposure to Increasing Doses of Ozone transcription profiling by array 06-21-2015 Ozone, the major component of air pollution, is an oxidant gas. Inhalation of high ambient levels o...
Gene expression profiles in dorsal skin of hairless mice orally administrated collagen hydrolysate transcription profiling by array 06-21-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Quiescence of Memory CD8+ T Cells Is Mediated by Regulatory T Cells through Inhibitory Receptor CTLA-4 transcription profiling by array 06-21-2015 Immune memory cells are poised to rapidly expand and elaborate effector functions upon reinfection. ...
The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis (RNA-Seq) RNA-seq of coding RNA 06-27-2015 SOX9 is a transcriptional activator required for chondrogenesis, and SOX5 and SOX6 are closely relat...
caArray_harri-00137: Predictors of Resistance to Preoperative Trastuzumab and Vinorelbine for HER2-Positive Early Breast Cancer transcription profiling by array 06-26-2015 To assess pathologic complete response (pCR), clinical response, feasibility, safety, and potential ...
Comprehensive genomic analysis of relapse neuroblastoma [methylation] methylation profiling by array 06-27-2015 Relapse neuroblastoma were characterized by sequencing, gene expression, arrayCGH and genome-wide me...
Microtubule Affinity-Regulating Kinase 2 is associated with DNA damage response and cisplatin resistance in non-small cell lung cancer. transcription profiling by array 06-27-2015 MARK2 expression is associated with the malignant phenotype, expression of DNA repair components, NF...
In vitro caloric restriction induces protective genes and functional rejuvenation in senescent SAMP8 astrocytes transcription profiling by array 06-27-2015 Astrocytes are key cells in brain aging, helping neurons to undertake healthy aging or otherwise let...
Transcription profiling by array of liver tissues from wild type and Rev-erb{alpha} knockout (Nr1d1-/-) mice to study direct targets of Nr1d1 in rhythmic (circadian) transcription transcription profiling by array 06-22-2015 Mammalian transcriptomes display complex circadian rhythms with multiple phases of gene expression t...