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Dataset Title Keywords Date Released Description
Epigenomic Evolution of Diffuse Large B-cell Relapse methylation profiling by high throughput sequencing 08-19-2015 Here we characterize an association between disease progression and DNA methylation in Diffuse Large...
Comprehensive genomic analysis of relapse neuroblastoma [methylation] methylation profiling by array 06-27-2015 Relapse neuroblastoma were characterized by sequencing, gene expression, arrayCGH and genome-wide me...
TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer RNA-seq of coding RNA
methylation profiling by high throughput sequencing
12-12-2015 5-hydroxymethylcytosine (5-mC) and gene expression profiling of T84 cell differentiation; 5-hmC prof...
Childhood Atopic Asthma methylation profiling by array
transcription profiling by array
12-03-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Epigenome analysis of clear cell renal cell carcinoma (ccRCC) tissue versus matched normal kidney tissue methylation profiling by array 12-08-2015 Genome wide DNA methylation profiling of clear cell renal cell carcinoma (ccRCC) tissue versus match...
Trans-effects of chromosome aneuploidies on DNA methylation patterns: DNA methylation analysis of Down syndrome in human brain tissues and cells methylation profiling by array 12-08-2015 Background: Trisomy 21 causes Down syndrome (DS), but the mechanisms by which the extra chromosome l...
Tet1 is a tumor suppressor of hematopoietic malignancy methylation profiling by high throughput sequencing 08-19-2015 Epigenetic pathways that regulate DNA methylation and chromatin modifications are frequently found t...
Whole Genome Bisulfite Sequencing (WGBS) of cKIT+ sorted cells from 57-137 day old fetal testes and ovaries. methylation profiling by high throughput sequencing 08-19-2015 We performed WGBS analyses on 6 human fetal samples at 53-137 days of development, 4 female and 2 ma...
Symmetrical dose-dependent DNA methylation profiles in children with deletion or duplication of chromosome 7q11.23 methylation profiling by array 08-19-2015 Genome wide DNA methylation in blood derived DNA from individuals with deletion or duplication of 7q...
Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells methylation profiling by array 12-26-2015 The human liver contains multiple cell types whose epigenetic patterns are undetermined. We examined...
Epo-Induced Erythroid Maturation Is Dependent on Plcγ1 Signaling methylation profiling by high throughput sequencing 01-11-2016 Erythropoiesis is a tightly regulated process. Development of red blood cells occurs through differe...
A probabilistic generative model for quantification of DNA modifications enables analysis of demethylation pathways [T-cells] methylation profiling by high throughput sequencing 01-10-2016 To characterize the largely unknown functions of oxidised methylcytosines (oxi-mC; 5hmC/5fC/5caC) in...
Methylome study in Nasopharyngeal Carcinoma (NPC) methylation profiling by array 01-10-2016 Aberrant methylation at the promoter region of tumor suppressors is frequently reported in NPC; howe...
Evaluation of Inter-Batch Differences in Stem-Cell Derived Neurons methylation profiling by array 12-19-2015 Genome wide DNA methylation profiling of Neurons derived from human induced pluripotent stem cells (...
Parallel single-cell bisulfite- and RNA-sequencing link transcriptional and epigenetic heterogeneity RNA-seq of coding RNA
methylation profiling by high throughput sequencing
12-26-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease methylation profiling by array 12-27-2015 Recent work has identified roles for environmental, genetic and epigenetic factors in AD risk. Motiv...
Whole-genome saliva and blood DNA methylation patterns in individuals with a respiratory allergy methylation profiling by array 01-09-2016 It has been suggested that the etiology of respiratory allergies (RA) can be partly explained by DNA...
Global DNA methylation landscape reveals roles of DNA methylation involved in the regulation of drug metabolizing enzyme [II] methylation profiling by array 06-21-2015 In order to elucidate the role of DNA methylation in the DME gene regulation, global DNA methylation...
Association of DNA Methylation with Acute Mania and Inflammatory Markers methylation profiling by array 06-27-2015 Genome wide DNA methylation profiling of serum samples from 20 individuals hospitalized with acute m...
Methylation microarray studies highlight PDGFA expression as a factor in biliary atresia methylation profiling by array 06-19-2015 Biliary atresia (BA) is a progressive fibro-inflammatory disorder that is the leading indication for...
Transcription and Imprinting Dynamics in Developing Postnatal Male Germline Stem Cells RNA-seq of coding RNA
ChIP-seq
methylation profiling by high throughput sequencing
12-01-2015 Paternal imprinting initiates in primordial germ cells (PGCs), and is considered largely completed a...
Epigenetic profiling in CD4 and CD8 T cells from Graves’ disease patients reveals changes in genes associated with T cell receptor signaling [methylation] methylation profiling by array 12-01-2015 In Graves’ disease (GD), a combination of genetic, epigenetic and environmental factors causes an ...
Methyl-CpG-binding domain (MBD) sequencing of neuroblastoma tumors methylation profiling by high throughput sequencing 11-30-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development RNA-seq of coding RNA
ChIP-seq
methylation profiling by high throughput sequencing
12-01-2015 Early mouse development is accompanied by dynamic changes in chromatin modifications, including G9a-...
Dexamethasone-stimulated DNA methylation of the epigenetic clock CpGs in peripheral blood methylation profiling by array 12-02-2015 Whole-genome DNA methylation (baseline and following GR-stimulation with 1.5 mg dexamethasone p.o.) ...
DNA methylation data from cell lines originating from patients with multiple myeloma methylation profiling by array 08-19-2015 We performed genome-wide DNA methylation profiling of KMS11, MM.1S, and RPMI8226 multiple myeloma ce...
DNA methylation data from 11 normal and 9 chronic periodontitis patients from site USC methylation profiling by array 08-19-2015 Microarray methylation (Infinium®HumanMethylation 450 BeadChip from Illumina) was performed on 11 n...
Gene expression and epigenetic sexual dimorphism in two jewel wasp species Nasonia vitripennis and Nasonia giraulti [Bisulfite-Seq] methylation profiling by high throughput sequencing 06-13-2015 The extraordinary range in the degree of sexual dimorphism (SD) among animal species is widely perce...
Cerebellum Illumina Inf 450 DNA methylation samples from HIV+ and HIV- human subjects methylation profiling by array 06-13-2015 Genome wide DNA methylation profiles of cerebellum from HIV positive and HIV negative human subjects...
DNA methylation levels of various brain regions from HIV+ and HIV- subjects methylation profiling by array 06-13-2015 Genome wide DNA methylation profiles of various human brain regions (cerebellum, occipital lobe, etc...
Lead exposure induces changes in 5-hydroxymethylcytosine clusters in CpG islands in human embryonic stem cells and umbilical cord blood methylation profiling by array 06-13-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Active Demethylation of Both Maternal and Paternal Genomes in Mouse Zygotes methylation profiling by high throughput sequencing 09-12-2016 The epigenomes of mammalian sperm and oocytes, characterized by gamete-specific 5-methylcytosine (5m...
An epigenetic memory of pregnancy in the mouse mammary gland methylation profiling by high throughput sequencing 08-19-2015 Pregnancy is the major modulator of mammary gland activity. It induces a tremendous expansion of the...
Base-resolution detection of N4-methylcytosine in genomic DNA using 4mC-TAB-seq methylation profiling by high throughput sequencing 08-19-2015 N4-methylcytosine is a major DNA modification integral to restriction-modification (R-M) systems in ...
Wnt inhibitory factor 1 (WIF1) is a marker of osteoblastic differentiation stage and is not silenced by DNA methylation in osteosarcoma methylation profiling by array
transcription profiling by array
08-19-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
DNA methylation changes in fetal germ cells exposed to endocrine disruptors and in the next generation [methylation set 1] methylation profiling by array 02-21-2015 According to recent reports, exposure to environmental endocrine disrupting chemicals (EDs) during p...
Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos (MRE-seq) methylation profiling by high throughput sequencing 02-21-2015 DNA methylation undergoes dynamic changes during development and cell differentiation. Recent genome...
MIWI2 and MILI have differential effects on piRNA biogenesis and DNA methylation RNA-seq of coding RNA
methylation profiling by high throughput sequencing
RNA-seq of non coding RNA
08-20-2015 In developing male germ cells, prospermatogonia, two Piwi proteins, MILI and MIWI2, use piRNA guides...
Altering TET dioxygenase levels within physiological range affects DNA methylation dynamics of HEK293 cells methylation profiling by array
methylation profiling by high throughput sequencing
transcription profiling by array
08-26-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Arterial endothelial methylome: Differential DNA methylation methylation profiling by high throughput sequencing 04-15-2015 Atherosclerosis preferentially develops in arterial regions where hemodynamic disturbed flow and oxi...
DNA methylation of matched primary-metastases medulloblastomas methylation profiling by array 04-04-2015 DNA methylation was generated from 11 pairs of matched primary-metastases medulloblastoma samples us...
ALK-dependent transcription factor networks are associated with epigenomic alterations of DNA methylation in ALCL methylation profiling by array 04-04-2015 Aberrant DNA methylation patterns of malignant cells allow for the study of the tumor phenotype and ...
Genome-wide Scan for Methylation Profiles in Breast Cancer methylation profiling by array 03-15-2015 Genome wide DNA methylation profiling of normal and breast cancer samples. The Illumina Infinium 450...
Parallel Epigenomic and Transcriptomic Responses to Viral Infection in Honey Bees (Apis mellifera) RNA-seq of coding RNA
methylation profiling by high throughput sequencing
04-02-2015 Here, we examined the transcriptional and epigenetic (DNA methylation) responses to viral infection ...
Identification of a DNA methylation signature in blood from subjects affected by Down syndrome methylation profiling by array 03-09-2015 Down syndrome is characterized by a wide spectrum of clinical signs, which include cognitive and end...
Direct but No Transgenerational Effects of Decitabine and Vorinostat on Male Fertility methylation profiling by high throughput sequencing 03-12-2015 Epigenetic drugs actively altering the epigenome of tumours have been developed for use in anti-canc...
Haploinsufficiency, but not defective paternal 5mC oxidation, accounts for the developmental defects of maternal Tet3 knockouts methylation profiling by high throughput sequencing 03-12-2015 DNA demethylation of paternal genome in zygotes takes place in various mammals including mice and hu...
Transcriptome analysis and Genome-wide DNA methylation maps in chronic lymphocytic leukemia cells determined by next-generation sequencing RNA-seq of coding RNA
methylation profiling by high throughput sequencing
03-01-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Treatment with GC/RA and combination with AZA/SAHA in MYC amplified and BRG1 mutant lung cancer cell lines methylation profiling by array
transcription profiling by array
09-12-2016 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
An integrated genetic-epigenetic analysis of schizophrenia: Evidence for co-localization of genetic associations and differential DNA methylation methylation profiling by array 08-06-2016 Background: Schizophrenia is a severe, highly heritable, neuropsychiatric disorder characterized by ...
Tet2-mediated DNA demethylation controls T cell cytokine expression [seq] methylation profiling by high throughput sequencing 04-18-2015 The conversion of 5-methylcytosine (5mC) into 5-Hydroxymethylcytosine (5hmC) by ten-eleven transloca...
DNA methylome analysis in infants from The Gambia / Aflatoxin / Seasonality study methylation profiling by array 04-27-2015 Genome wide DNA methylation profiling in infant's blood from a mother/child cohort in The Gambia. Th...
Exploration of hydroxymethylation in Kagami-Ogata syndrome caused by hypermethylation of imprinting control regions methylation profiling by array 09-05-2015 5-hydroxymethylcytosine (5hmC), converted from 5-methylcytosine (5mC) by Tet enzymes, has recently d...
Epigenome signatures during gastric carcinogenesis based on next generation sequencing analysis [MBD-Seq] methylation profiling by high throughput sequencing 09-05-2015 Because gastric cancer cells already had genetic and epigenetic alterations which can affect the gas...
Genome wide DNA methylation profiling of hyperplasias, primary endometrial cancer and metastases methylation profiling by array 09-05-2015 The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profile...
Global DNA methylation changes in Nile tilapia gonad during high-temperature induced masculinization methylation profiling by high throughput sequencing 09-06-2015 In fish, the sex determining mechanisms can broadly be classified as genotypic (GSD), temperature-de...
Patterns of somatic uniparental disomy identify driver tumor suppressor genes in colorectal cancer methylation profiling by array
comparative genomic hybridization by array
genotyping by array
09-05-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2’-dC upon inhibition of ribonucleotide reductase-wide methylation profiling by high throughput sequencing 08-29-2015 Background: DNA methylation is important for maintenance of the silent state of genes on the inactiv...
Epigenetic screen of metastasis-driving genes in osteosarcoma methylation profiling by array
transcription profiling by array
08-29-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
DNA Methylation of African Americans from the Grady Trauma Project methylation profiling by array 09-04-2015 Childhood and cumulative exposure to trauma increases an individual's lifetime risk for psychiatric ...
DNA methylation profiling in WT-AG-haESCs, DKO-AG-haESCs and round spermatids methylation profiling by high throughput sequencing 08-19-2015 We generated RRBS data to analyse the DNA methylation profiling among WT-AG-haESCs, DKO-AG-haESCs an...
Epigenome analysis of the effects of JQ1 on DNA methylation methylation profiling by array 08-19-2015 Genome wide DNA methylation profiling of four female lymphoblastoid cell lines treated with DMSO con...
Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice methylation profiling by high throughput sequencing 08-20-2015 Heritable epigenetic factors can contribute to complex disease etiology. In this study we examine, o...
Intra-individual tumoral heterogeneity of ovarian serous adenocarcinomas methylation profiling by array
comparative genomic hybridization by array
08-09-2016 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Altered patterns of hydroxymethylation regulate oncogenic pathways in pancreatic cancer methylation profiling by high throughput sequencing 08-06-2016 Transcriptional deregulation of oncogenic pathways is a hallmark of cancer, and can be due to epigen...
The epigenetic signature of systemic insulin resistance in obese women [SC] methylation profiling by array 08-06-2016 Impaired ability of insulin to stimulate cellular glucose uptake and regulate metabolism, that is in...
Regulation of Promoter and Enhancer Histone Landscape by DNA Methylation in Embryonic Stem Cells RNA-seq of coding RNA
ChIP-seq
methylation profiling by high throughput sequencing
08-02-2016 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Widespread natural variation of DNA methylation within angiosperms RNA-seq of coding RNA
methylation profiling by high throughput sequencing
RNA-seq of non coding RNA
09-02-2016 DNA methylation is a chemical modification of DNA that can be faithfully inherited across generation...
DNA methylation analysis of neuroblastoma cell lines treated with epigenetic drugs methylation profiling by array 09-08-2016 The impact of drugs inhibiting DNA methylation (5-aza-2'-deoxycytodine, DAC) and EZH2 (EPZ-6438) on ...
DNA methylation patterns in perpheral blood samples from pre- and post-pubertal boys and girls methylation profiling by array 08-22-2016 The COPENHAGEN Puberty Study is a combined cross sectional and longitudinal population based cohort ...
Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomas methylation profiling by array 07-24-2016 DNA methylation profiling of heterogeneous head and neck squamous cell carcinoma (HNSCC) cohorts has...
Transcriptomic and Epigenetic Signatures of Mouse Cardiac Progenitor Cells methylation profiling by array
transcription profiling by array
07-24-2016 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Genome-wide methylation profiles in primary intracranial germ cell tumors indicate primordial germ cell origin of germinoma [Agilent] methylation profiling by array 04-11-2016 The pathogenesis of intracranial germ cell tumors (iGCTs) is not yet fully uncovered despite exhaust...
Genomic distribution of 5-hydroxymethylcytosine in mouse kidney and its relationship with gene expression ChIP-seq
methylation profiling by high throughput sequencing
04-11-2016 Ten-Elven Translocation (TET) proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytonsie (5h...
EpiPrem Study methylation profiling by array 04-08-2016 Longitudinal samples were collected from neonates in the NICU at the Royal Women’s Hospital in Mel...
Integrated epigenomic analyses of enhancer as well as promoter regions in gastric cancer comparative genomic hybridization by array
RNA-seq of coding RNA
methylation profiling by high throughput sequencing
04-03-2016 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Methylation profiling of human samples using MeDIP-seq method. EGA study. methylation profiling by high throughput sequencing 05-16-2016 Aim: We aim to compare current (MeDIP-seq), new (Illumina Infinium 450K BeadChip) and future (PacBio...
DNA methylation profiles of human bone samples methylation profiling by array 06-06-2015 The main goal of the study was to measure the epigenetic age (also known as DNA methylation age) of ...
A novel epigenetic regulated gene and involved in phenotypic switch classifies primary melanomas depending on the aggressiveness grade (Illumina) methylation profiling by array 05-22-2015 Loss of methylation of a GTPase-activating protein in melanoma mediates higher proliferation, lower ...
Integration of transcriptome and methylome analyses to dissect molecular pathogenesis of primary aldosteronism: comparision between aldosterone-producing adenomas and adjacent adrenal glands methylation profiling by array
transcription profiling by array
05-22-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
An alternative pluripotent state confers interspecies chimaeric competency [WGBS] methylation profiling by high throughput sequencing 05-22-2015 In this study, we show that by simple modulation of extrinsic signaling pathways, a new class of plu...
Gender-specific post-natal demethylation and establishment of epigenetic memory RNA-seq of coding RNA
methylation profiling by high throughput sequencing
05-09-2015 DNA methylation patterns are set up in a relatively fixed programmed manner during normal embryonic ...
DNA methylation profiles in alcohol-associated hepatocellular carcinoma methylation profiling by array 05-09-2015 Alcohol is a major risk factor for hepatocellular carcinoma (HCC) although the mechanisms underlying...
IP of 5-hydroxymethylcytosine (5-hmC) enriched DNA fragments from control ,PB treated mouse livers , resulting Ctnnb1 mutated PB liver tumours and PB minus Ha-Ras mutate liver tumour methylation profiling by array 05-22-2016 Through the analysis of mouse liver tumours promoted by distinct routes (DEN exposure alone, DEN exp...
Methylation Profile of dry seed from Arabidopsis ddcc mutant methylation profiling by high throughput sequencing 04-30-2015 The role of on-CG methylation in seed development and dormancy remains unknown. There are four genes...
DNA IP for 5hmC modified CpGs in the liver of control mice and a Tet1 -/- mouse liver [hmeDIP-seq] methylation profiling by high throughput sequencing 05-22-2016 Through the analysis of mouse liver tumours promoted by distinct routes (DEN exposure alone, DEN exp...
Genome-wide methylation profiles of menstrual blood and vaginal fluid methylation profiling by array 05-22-2016 The ability to predict the type of tissues or cells from molecular profiles of crime scene samples h...
DNA-methylation profiling of monocyte genomic DNAs collected from participants of Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study methylation profiling by array 05-22-2016 Study the association of DNA-methylation and metabolic memory by examing DNA-methylation alternation...
DNA-methylation profiling of Whole blood genomic DNAs collected at EDIC baseline and monocytes at EDIC years 16/17 yrs from participants of DCCT/EDIC study methylation profiling by array 05-22-2016 DNA-methylation profiling of Whole blood genomic DNAs collected at EDIC baseline and monocytes at ED...
Profiling of epigenetic and transcriptomic landscapes in normal mouse liver, phenobarbital exposed mouse livers and mouse liver tumours methylation profiling by array
RNA-seq of coding RNA
ChIP-seq
methylation profiling by high throughput sequencing
05-22-2016 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Assessment of epigenetic variation in human iPS cells Medip methylation profiling by high throughput sequencing 05-18-2016 n order to progress human induced pluripotent stem cells (hiPSCs) towards the clinic, several outsta...
Whole genome characterisation of chemoresistant ovarian cancer [Illumina_450K_Methylation] methylation profiling by array 05-24-2015 Patients with high-grade serous ovarian cancer (HGSC) have experienced little improvement in overall...
caArray_EXP-620: TCGA (Coad): Analysis of DNA Methylation for COAD using Illumina Infinium HumanMethylation450 platform (Jhu-usc) methylation profiling by array 05-22-2015 TCGA Analysis of DNA Methylation for COAD using Illumina Infinium HumanMethylation450 platform EXP-6...
DNA methylation profiles of multiple human tissues methylation profiling by array 06-06-2015 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Genome-wide analysis of DNA methylation in drug-tolerant cancer cell subpopulations methylation profiling by array 05-30-2015 Cancer relapse after curative treatment is thought to originate from drug-tolerant and invisible can...
Genome-wide methylation profiles of forensically relevant body fluids [Set2] methylation profiling by array 05-30-2015 The ability to predict tissue type and donor’s age from molecular profiles of crime scene samples ...
DNA methylation response of hematopoietic stem cells to recombinant lentiviral vector infection methylation profiling by array 09-21-2015 Human cord blood CD34+ cells respond to the infection with LV by modifying the methylation profile o...
Methylation changes in pre MAPKi treatment and post MAPKi resistance Melanomas methylation profiling by array 09-20-2015 Melanoma resistance to MAPK- or T cell checkpoint-targeted therapies represents a major clinical cha...
Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers methylation profiling by array 09-19-2015 Background: The mechanisms of how genetic variants (SNPs) identified in genome-wide association stud...
The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women methylation profiling by array 09-20-2015 Background Obesity is associated with changes in fat cell gene expression and metabolism. What drive...