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Displaying 20 of 68 results for "TLR7"
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Title ID Description Date Released
Toll-like receptor 7 is a primary sensor of malaria infection E-GEOD-41496 Microarray profiling of amplified total splenic RNA isolated from TLR9-, TLR7-, UNC93b1- or MYD88- d... 09-21-2013
Dysregulated TLR7 signaling drives anemia via development of hemophagocytic macrophages E-GEOD-70520 The debilitating autoimmune disease Systemic Lupus Erythematosus (SLE) is closely associated with To... 07-01-2016
Sustained Efficacy and Seroconversion with the Toll-Like Receptor 7 Agonist GS-9620 in the Woodchuck Model of Chronic Hepatitis B E-GEOD-67935 Background & Aims: New therapies for chronic hepatitis B (CHB) are urgently needed since current tr... 04-16-2015
Suppression of molecular inflammatory pathways by Toll-like Receptor 7, 8, and 9 antagonists in a model of IL-23-induced skin inflammation E-GEOD-50400 Psoriasis is a complex inflammatory disease resulting from the activation of T helper (Th) 1 and Th1... 01-21-2014
Bruton's Tyrosine Kinase Regulates TLR9 but not TLR7 Signaling in Human pDCs E-GEOD-41825 Plasmacytoid dendritic cells (pDCs) can be activated by the endosomal TLRs, and contribute to the pa... 10-24-2015
Transcription profiling of mouse embryonic fibroblasts from wild type and IRAK-4 kinase dead animals stimulated with IL-1b for different durations to identify IRAK-4 kinase-dependent IL-1b response genes E-GEOD-6789 IRAK-4 is an essential component of the signal transduction complex downstream of the IL-1- and Toll... 11-15-2007
Cell intrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses E-GEOD-58756 Endosomal Toll-like receptors (TLRs) play an important role in the etiology of systemic autoimmune d... 03-04-2015
Treatment of human monocytes with TLR7 or TLR8 agonists E-GEOD-64480 Goal was to detect differences in response to TLR7 versus TLR8 agonists in human monocytes from heal... 12-24-2014
Gene profiling in the colon after depletion and activation of TLR3 and TLR7 signals E-GEOD-79241 TLR3 and TLR7 are critical recognition receptor which reacts with viruses. TLR3 and TLR7 contribute ... 07-05-2016
Differential gene expression in wild-type versus Yaa mutant mouse spleen cells E-GEOD-9287 T cells from many patients with systemic lupus erythematosus are hypoproliferative in response to TC... 12-15-2009
Transcription profiling of mouse model of asthma reveals the effects of resiquimod treatment on the asthma transcriptome E-GEOD-13032 Resiquimod is a nucleoside analog belonging to the imidazoquinoline family of compounds which is kno... 10-26-2008
TLR3, TLR7, and TLR9 stimulation in murine dorsal root ganglion neurons E-GEOD-27579 TLR3, TLR7, and TLR9 stimulation induces many mouse inflammatory and autoimmune cytokines or immune ... 03-02-2011
Transcription profling by array of mouse dendritic cells treated with bacterial RNA packaged in DOTAP or TLR7 agonist R848 E-MTAB-1139 Murine dendritic cells were derived from bone-marrow of 4 mice using GM-CSF. The DC were treated wit... 05-08-2012
p53 amplifies Toll-like receptor 5 response in MCF-7 cells E-GEOD-72359 Using gene expression profiling we characterize the global effect of p53 on the TLR5-mediated transc... 08-26-2015
TLR7 gene duplication accelerates autoimmunity and promotes nucleolar-specific B cells E-GEOD-4445 Systemic autoimmune diseases such as lupus and scleroderma are characterized by the loss of toleranc... 07-01-2010
Stimulation of isolated plasmacytoid dendritic cells (pDCs) with TLR9 agonist CpG C (CpG) and TLR7 agonist imiquimod (IMQ) E-GEOD-79272 The purpose of this experiment was to assess the genes upregulated when pDCs were stimulated with TL... 03-17-2016
Oncogenic MyD88 Mutants Require Toll-like Receptors E-GEOD-47147 In the activated B-cell-like (ABC) subtype of diffuse large B cell lymphoma (DLBCL), the most freque... 05-21-2014
DC populations incubated with rAd5, rAd28, rAd35, TLR7/8-ligand, or unexposed E-GEOD-37128 Recombinant adenovirus vectors (rAds) are being investigated as vaccine delivery vehicles in pre-cli... 07-10-2012
Differences in the transcriptomic response of human adult and neonatal dendritic cell subsets to TLR7/8 stimulation E-GEOD-67057 Previous studies have shown that purified dendritic cells (DCs) have cell-intrinsic, age-dependent d... 06-30-2015
CD103+ Conventional Dendritic Cells are Critical for TLR-dependent Host Defense against an Endemic Fungal Pathogen E-GEOD-70505 Innate immune cells shape the host response to microbial pathogens. Here we studied the role of TLR7... 06-28-2016