Expression analysis of wild-type and Tfam heterozygous knockout ( Tfam+/-) murine embryonic fibroblasts (MEFs)
The goal of this analysis was to utilize microarray profiling to identify basal alterations in gene ...
Drosophila CNS mitochondrial DNA dysfunction microarray
Mitochondrial DNA (mtDNA) encodes essential components of the respiratory chain and loss of mtDNA le...
POLRMT regulates the switch between replication-primer formation and gene expression of mammalian mtDNA
Mitochondria are vital in providing cellular energy via their oxidative phosphorylation system, whic...
TFAM ChIP-seq in HeLa cells
ChIP-seq data characterizing the occupancy of TFAM over the mitochondrial and nuclear genomes in HeL...
Expression data for 2-month-old wild type and Tfam-SCKO (MPZ- Tfam KO) sciatic nerves
Gene expression analysis of 2-month-old Ctrl and Tfam-SCKO mice. At this age mitochondrial function ...
Oxidized mitochondrial nucleoids released by neutrophils drive type I Interferon production in human lupus
Autoantibodies against nucleic acids and excessive type I Interferon (IFN) are hallmarks of human S...
TGFβ contributes to impaired exercise response by suppression of mitochondrial key regulators in skeletal muscle
substantial number of people at risk to develop type 2 diabetes could not improve insulin sensitivit...
Expression data from human blood from MELAS patients and controls
Background: The heteroplasmic mitochondrial DNA (mtDNA) mutation A3243G causes the MELAS syndrome as...
Transcription profiling of skeletal muscle form patients suffering from sepsis-induced muliple organ failure
Septic patients treated in the intensive care unit (ICU) often develop multiple organ failure includ...
Transcription profiling by array of Drosophila larvae mutant for Delg
Nuclear transcription factors drive mitochondrial mass by regulating the expression of genes encodin...
Mitofusin 2 expression in muscle decreases during aging and generates a gene signature characteristic of aged muscle
Mitochondrial fusion and fission proteins regulate mitochondrial quality control and mitochondrial m...
Transcription profiling by array of Fundulus heteroclitus livers based on sex, mitochondrial genotype, and hypoxia
This experiment profiled gene expression in livers of individual F. heteroclitus based on sex, mitoc...
Whole cell mRNA expression profiling in control and complex I deficient patient fibroblasts incubated with DMSO, AICAR, chloramphenicol, and resveratrol
Background: Transcription control of mitochondrial metabolism is essential for cellular function. A ...
Transcription profiling of mouse TSC2-/- embryonic fibroblasts: vehicle-treated, rapamycin-treated, gfp-infected, and pgc-1alpha-infected samples reveals the mTOR pathway controls mitochondrial gene expression and respiration through the YY1/PGC-1alpha transcriptional complex
Mitochondrial oxidative function is tightly controlled to maintain energy homeostasis in response to...
To identify ATFS-1 target genes during mitochondrial stress
To better understand genome coordination and OXPHOS recovery during mitochondrial dysfunction, we ex...
A Systems Approach for Decoding Mitochondrial Retrograde Signaling Pathways
The mitochondrial and nuclear genomes contribute to mitochondrial function, and when mitochondrial f...
Transcription profiling by high throughput sequencing of Arabidopsis mutants that are defective in mitochondrial proteins
Mitochondria are crucial for plant viability and are able to communicate information on their functi...
Transcription profiling by array of skeletal muscle in TypeII diabetes patients
Skeletal muscle mitochondrial dysfunction is secondary to T2DM and can be improved by long-term regu...
Transcription profiling of mouse HtrA2 knockout mice with a movement disorder (possible Parkinsons model) reveals mitochondrial dysfunction by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response
Cellular stress responses can be activated following functional defects in organelles such as mitoch...
Transcription profiing of a yeast strain containing 2 extra copies of Abf2p compared to its wild type counterpart
We compared the RNA expression profile from a Saccharomyces cerevisiae yeast strain (3xABF2) contain...