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Displaying 20 of 36 results for "SLC46A1"
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Dataset Title Dataset ID Primary Publications Keywords
Crystal structure of human folate receptor alpha in complex with novel antifolate AGF183 PDB:5IZQ Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor alpha and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis.
T
SIGNALING PROTEIN Folate receptor alpha SIGNALING PROTEIN
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND (S)-2-({5-[3-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)-PROPYL]-THIOPHENE-3-CARBONYL}-AMINO)-PENTANEDIOIC ACID PDB:4ZZ2 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor alpha and the Proton-Coupled Folate Transporter in Human Tumors.
6
TRANSFERASE/TRANSFERASE INHIBITOR
gar transformylase
antifolate
TRANSFERASE-TRANSFERASE INHIBITOR complex
Structural Genomics
Human GAR transformylase in complex with GAR and pemetrexed PDB:4ZZ3 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor alpha and the Proton-Coupled Folate Transporter in Human Tumors.
6
transferase/transferase inhibitor
gar transformylase
antifolate
transferase-transferase inhibitor complex
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND (S)-2-({4-[3-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)-PROPYL]-THIOPHENE-2-CARBONYL}-AMINO)-PENTANEDIOIC ACID PDB:4ZZ1 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor alpha and the Proton-Coupled Folate Transporter in Human Tumors.
6
TRANSFERASE/TRANSFERASE INHIBITOR
gar transformylase
antifolate
TRANSFERASE-TRANSFERASE INHIBITOR complex
Human GAR transformylase in complex with GAR and (4-{[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)ethyl]amino}benzoyl)-L-glutamic acid (AGF183) PDB:5J9F Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor alpha and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis.
T
ligase/ligase inhibitor
gar transformylase
antifolate
ligase-ligase inhibitor complex
Structure of the Hcp1 protein from E. coli EAEC 042 pathovar, mutants N93W-S158W PDB:4HKH Structure of the Hcp1 protein from E. coli EAEC 042 pathovar, mutants N93W-S158W
S
PROTEIN BINDING PROTEIN BINDING
Structure of DNA G-quadruplex adopted by ALS and FTD related GGGGCC repeat with G21 to Br-G21 substitution PDB:2N2D Solution structure of a DNA quadruplex containing ALS and FTD related GGGGCC repeat stabilized by 8-bromodeoxyguanosine substitution.
DNA
DNA
g-quadruplex
antiparallel
Hcp1 protein from Acinetobacter baumannii AB0057 PDB:4W64 Crystal Structure of Hcp from Acinetobacter baumannii: A Component of the Type VI Secretion System.
Hcp1 family
Crystal structure of Type Six Secretion System protein PDB:3WX6 Extended Loop Region of Hcp1 is Critical for the Assembly and Function of Type VI Secretion System in Burkholderia pseudomallei.
E
T6SS protein
Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Manganese(III)-porphyrin PDB:3QUH Molecular basis of recognition of antibacterial porphyrins by heme-transporter IsdH-NEAT3 of Staphylococcus aureus.
M
HEME-BINDING PROTEIN Heme Binding Heme Transport Heme HEME-BINDING PROTEIN
Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Gallium-porphyrin PDB:3QUG Molecular basis of recognition of antibacterial porphyrins by heme-transporter IsdH-NEAT3 of Staphylococcus aureus.
M
HEME-BINDING PROTEIN Heme Binding Heme Transport Heme HEME-BINDING PROTEIN
Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin PDB:3VTM Selective binding of antimicrobial porphyrins to the heme-receptor IsdH-NEAT3 of Staphylococcus aureus
S
HEME-BINDING PROTEIN Heme binding Heme transport HEME-BINDING PROTEIN
Crystal Structure of P450BioI in complex with tetradecanoic acid ligated Acyl Carrier Protein PDB:3EJB Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
S
Protein-Protein Complex Carrier Protein Heme
Crystal Structure of P450BioI in complex with hexadec-9Z-enoic acid ligated Acyl Carrier Protein PDB:3EJD Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
S
Protein-Protein Complex Carrier Protein Heme
Crystal Structure of P450BioI in complex with octadec-9Z-enoic acid ligated Acyl Carrier Protein PDB:3EJE Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
S
Protein-Protein Complex Carrier Protein Heme
Improved coordinates for Escherichia coli O157:H7 heme degrading enzyme ChuS. PDB:4CDP Structure of the Escherichia Coli O157:H7 Heme Oxygenase Chus in Complex with Heme and Enzymatic Inactivation by Mutation of the Heme Coordinating Residue His-193.
S
HEME DEGRADATION
Crystal Structure Analysis of ChuS, an E. coli Heme Oxygenase PDB:1U9T Identification of an Escherichia coli O157:H7 heme oxygenase with tandem functional repeats
I
OXIDOREDUCTASE
Structural Genomics
The Montreal-Kingston Bacterial Structural Genomics Initiative
Structural Repeat
Central Beta Sheet
flanked by Alpha helices
BSGI
OXIDOREDUCTASE
Cryo-EM structure of mammalian respiratory supercomplex I1III2IV1 PDB:5GUP Structure of Mammalian Respiratory Supercomplex I1III2IV1
ELECTRON TRANSPORT
Cryo-EM
Mammalian
Respiratory
Supercomplex
ELECTRON TRANSPORT
Crystal structure of nitrophorin 2 complex with NO PDB:1T68 Conformational change and heme ruffling in nitrophorin 2, a nitric oxide carrier from kissing bug
C
TRANSPORT PROTEIN heme TRANSPORT PROTEIN
STRUCTURE DETERMINATION OF THE FERROCYTOCHROME C2 FROM RHODOPSEUDOMONAS PALUSTRIS PDB:1I8P Cleavage of the iron-methionine bond in c-type cytochromes: crystal structure of oxidized and reduced cytochrome c(2) from Rhodopseudomonas palustris and its ammonia complex.
ELECTRON CARRIER HEME PROTEIN