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Displaying 20 of 49 results for "MDM2"
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Dataset Title Keywords Date Released Description
Mdm2 enhances stemness-promoting chromatin modifications through the Polycomb Repressor Complex 2 in a p53-Independent Manner [RNA-Seq] RNA-seq of coding RNA 01-02-2016 The Mdm2 oncoprotein ubiquitinates and antagonizes p53 but may also carry out p53-independent functi...
Mdm2 enhances stemness-promoting chromatin modifications through the Polycomb Repressor Complex 2 in a p53-Independent Manner [ChIP-Seq] ChIP-seq 01-02-2016 The Mdm2 oncoprotein ubiquitinates and antagonizes p53 but may also carry out p53-independent functi...
Mdm2 enhances stemness-promoting chromatin modifications through the Polycomb Repressor Complex 2 in a p53-Independent Manner [HCT116 microarray] transcription profiling by array 01-02-2016 The Mdm2 oncoprotein ubiquitinates and antagonizes p53 but may also carry out p53-independent functi...
Mdm2 enhances stemness-promoting chromatin modifications through the Polycomb Repressor Complex 2 in a p53-Independent Manner [hMSC microarray] transcription profiling by array 01-02-2016 The Mdm2 oncoprotein ubiquitinates and antagonizes p53 but may also carry out p53-independent functi...
Transcription profiling by array of Mdm2 knock out mice N/A 07-03-2014 Analyzed gene expression in 3-day old mice lacking Mdm2 in the intestine
mRNA expression profile in vascular smooth muscle cells (VSMCs) after inducing calcification transcription profiling by array 12-01-2015 Vascular calcification (VC) is often associated with cardiovascular and metabolic diseases. However,...
SIRT6 phosphorylation SIRT6
phosphorylation
07-06-2016 Sirtuin 6 (SIRT6) is associated with longevity and was recently established as a tumor suppressor. H...
Effect of wtp53-reactivating drug RITA on HCT116 cells transcription profiling by array 03-27-2012 Since its discovery as a tumour suppressor some fifteen years ago, the transcription factor p53 has ...
Gene-expression profiles of liver and hepatocellular carcinoma induced by diethylnitrosamine (DEN) in KLF6 +/- and wild type KLF6 mice. transcription profiling by array 08-16-2011 Gene-expression profiles of liver and hepatocellular carcinoma induced by diethylnitrosamine (DEN) i...
Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis. N/A Oesophageal adenocarcinoma (EAC) incidence is rapidly increasing in Western countries. A better unde...
Mdm2 enhances stemness-promoting chromatin modifications through the Polycomb Repressor Complex 2 in a p53-Independent Manner RNA-seq of coding RNA
ChIP-seq
transcription profiling by array
01-02-2016 This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Comparative genomic hybridization of frozen salivary or pulmonary adenoid cystic carcinoma samples and normal tissue to identify copy number alterations comparative genomic hybridization by array 05-02-2014 Adenoid cystic carcinoma (AAC) is a rare but distinctive tumor. Array comparative genomic hybridizat...
Cotranscriptional exon skipping in the genotoxic stress response transcription profiling by array 06-10-2011 Pre-mRNA splicing is functionally coupled to transcription, and genotoxic stresses can enhance alter...
Acute and long-term effects of mutant p53 in vivo [Thymus] transcription profiling by array 01-14-2013 The specific roles of mutant p53’s dominant-negative (DN) or gain-of-function (GOF) properties in ...
Human adenoid cystic carcinoma vs. human normal lymphocyte comparative genomic hybridization by array 05-02-2014 We analyzed ten adenoid cystic carcinomas of head and neck by array-based comparative genomic hybrid...
Transcription profiling by array of human HCT116 cells treated with Nutlin-3 (an inhibitor of mdm2 and p53 interaction) or DMSO control to study p53-regulated transcription transcription profiling by array 05-01-2015 HCT116 microarray done 12 hours after treatment with DMSO (control) or Nutlin Total RNA from HCT116 ...
Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) of BJ cells treated with Nutlin-3a, an MDM2 inhibitor, which induces p53. other
RNA-seq of coding RNA
05-03-2014 We applied in parallel RNA-Seq and Ribosome-profiling analyses to immortalized human primary BJ fibr...
Genome-wide map of p53 binding sites by ChIP-seq in human lymphoblastoid cell lines treated with nutlin-3 ChIP-seq 10-23-2013 We have used chromatin immune-precipitation with parallel sequencing (ChIP-Seq) technology to identi...
Mutations in histone and other genes in MLL2-impaired human and mouse cells DNA-seq 04-15-2016 We used human or mouse MLL2-impaired cells (including a human DSET MLL2 cell line,) as well as their...
CD99 triggering induces a novel processes of death in Ewing's sarcoma cells involving reactivation of p53 functions and RAS upregulation. transcription profiling by array 02-08-2015 CD99 is a transmembrane protein, whose expression is constantly associated to Ewing’s Sarcoma (EWS...