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Displaying 20 of 32 results for "GET4"
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Dataset Title Dataset ID Primary Publications Keywords
Crystal structure of an ATP-bound Get3-Get4-Get5 complex from S.cerevisiae PDB:4PWX Crystal structure of ATP-bound Get3-Get4-Get5 complex reveals regulation of Get3 by Get4.
C
TRANSPORT PROTEIN TRANSPORT PROTEIN
Crystal structure of C. therm. Get4 PDB:3LPZ The structure of Get4 reveals an alpha-solenoid fold adapted for multiple interactions in tail-anchored protein biogenesis.
T
PROTEIN TRANSPORT Protein targeting tail-anchored protein biogenesis PROTEIN TRANSPORT
CRYSTAL STRUCTURE OF S. CEREVISIAE GET4-GET5 COMPLEX PDB:2WPV Crystal Structure of Get4-Get5 Complex and its Interactions with Sgt2, Get3, and Ydj1.
C
PROTEIN BINDING GOLGI-ER TRAFFICKING TAIL-ANCHORED PROTEIN PROTEIN BINDING GET4
2.8 A crystal structure of a Get3-Get4-Get5 intermediate complex from S.cerevisiae PDB:5BW8 Mechanism of Assembly of a Substrate Transfer Complex during Tail-anchored Protein Targeting.
M
Hydrolase-Transport complex
Crystal structure of S. cerevisiae Get4 in complex with an N-terminal fragment of Get5 PDB:3LKU Structural characterization of the Get4/Get5 complex and its interaction with Get3.
S
PROTEIN BINDING PROTEIN BINDING
6.0 A Crystal structure of a Get3-Get4-Get5 intermediate complex from S.cerevisiae PDB:5BWK Mechanism of Assembly of a Substrate Transfer Complex during Tail-anchored Protein Targeting.
M
Hydrolase-Transport complex
The novel SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity PDB:5CPR The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.
T
protein lysine transferase
Crystal structure of the Sgt2 TPR domain from Aspergillus fumigatus PDB:3SZ7 A structural model of the Sgt2 protein and its interactions with chaperones and the Get4/Get5 complex.
A
TPR domain Get4
Solution structure of the Get5 carboxyl domain from S. cerevisiae PDB:2LNZ Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 Complex.
G
PROTEIN BINDING PROTEIN BINDING
Crystal structure of the Get5 carboxyl domain from S. cerevisiae PDB:3VEJ Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 Complex.
G
PROTEIN BINDING PROTEIN BINDING
Solution structure of the Get5 carboxyl domain from A. fumigatus PDB:2LO0 Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 Complex.
G
PROTEIN BINDING PROTEIN BINDING
co-crystal structure of Pim1 with compound 3 PDB:4RPV The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors.
TRANSFERASE-TRANSFERASE INHIBITOR complex
Crystal structure of the VEGFR2 kinase domain in complex with a pyridyl-pyrimidine benzimidazole inhibitor PDB:3EWH Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase.
Transferase
angiogenesis
receptor tyrosine kinase
DFG-out
Transferase
Crystal structure of benzamide 9 bound to AuroraA PDB:3O50 Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor.
kinase domain
Crystal structure of human Pim-1 kinase in complex with an aminooxadiazole-indole inhibitor. PDB:4TY1 The discovery and optimization of aminooxadiazoles as potent Pim kinase inhibitors.
serine/threonine-protein kinase
Evolution of a highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor PDB:2P4I Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor.
Transferase
Tie-2 Kinase Inhibitor triazine
Transferase
Synthesis, Structural Analysis, and SAR Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors PDB:2OO8 Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors.
TRANSFERASE
Kinase
TRANSFERASE
Crystal structure of human Pim-1 kinase in complex with a thiadiazolamine-indole inhibitor. PDB:4WT6 Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors.
serine/threonine protein kinase
Crystal structure of human Pim-1 kinase in complex with an azaspiro pyrazinyl-indazole inhibitor. PDB:4WRS The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors.
serine/threonine protein kinase
Structure of AuroraA with pyridyl-pyrimidine urea inhibitor PDB:3EFW Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase.
Serine/threonine-protein kinase Transferase-Inhibitor complex