FANCD2 Activates Transcription of TAp63 and Suppresses Tumorigenesis
Fanconi Anemia (FA) is a rare genetic disorder characterized by an increased susceptibility to squam...
Fanconi anemia proteins interact with CtBP1 and modulate the expression of the Wnt antagonist Dickkopf-1
Fanconi anemia (FA) is a genetic disorder characterized by congenital abnormalities, bone marrow fai...
Gene expression profiles of murine Runx1;Runx3 double deficient cKit+Sca1+Lin- hematopoietic stem/progenitor cells
The RUNX genes encode for transcription factors involved in development and human disease. RUNX1 and...
BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair
Brca1 is required for DNA repair by homologous recombination (HR) and normal embryonic development. ...
Oxymetholone therapy of Fanconi anemia suppresses osteopontin transcription and induces hematopoietic stem cell cycling
We used Fancd2-/- mice to understand its mechanism of action. Transcriptome analysis of cKit+ Sca1+ ...
Molecular Profiling of Metastatic Prostate Carcinoma Reveals Substantial Inter-individual and Limited Intra-individual Diversity: Implications for Precision Oncology
Prostate cancers exhibit a spectrum of molecular aberrations of which a substantial subset are amena...
Gene expression profiling reveals activation of the FA/BRCA pathway in advanced squamous cervical cancer with intrinsic resistance and therapy failure
Twenty-one patients with locally advanced squamous cell carcinoma were enrolled in this study. Prima...
Fatty acid composition of developing tree peony (Paeonia section Moutan DC.) seeds and transcriptome analysis during seed development
Tree peony (Paeonia ostii section Moutan DC.) is known for its excellent ornamental and medicinal va...
Imatinib therapy of chronic myeloid leukemia restores the expression levels of key genes for DNA damage and cell cycle progression
Background: Chronic myeloid leukemia (CML) is a malignant clonal disorder of the hematopoietic syste...
Gene expression profile of sporadic and PSEN1 early-onset Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common neurodegenerative dementia. Around 10% of cases presen...
Differentiating 3T3-L1 adipocytes, introduced with siRNA against aof2 and rfk genes, or treated with tranylcypromine
Adipogenic differentiation and metabolic adaptation are initiated through transcriptional and epigen...
Characterization of the LFR Genomic Islet in Staphylococcus aureus CC30
We report the application of RNA-Seq to assess transcriptional profiles of S. aureus CC30 strains wi...
Expression data from Hematopoietic stem cells
Objective: Microarray analysis was used to determine the molecular mechanism underlying Fancd2 and F...
Transcription profiling of Pseudomonas aeruginosa PAO1-psrA::Tn vs. PAO1 in LB
b-Oxidative enzymes for fatty acid degradation (Fad) of long-chain fatty acid (LCFA), a component of...
Exploring the role of sigma factor gene expression on production by Corynebacterium glutamicum: sigma factor H and FMN as example
Bacteria are known to cope with environmental changes by using alternative sigma factors binding to ...
D-Glutamate Utilization in Pseudomonas aeruginosa PAO1
D-Glutamate (D-Glu), an essential component of peptidoglycans, can be utilized as carbon and nitroge...
Cis- and trans-Regulation of Pneumococcal spxB
Pyruvate oxidase encoded by spxB is a major virulence factor in the human respiratory pathogen Strep...
Gene expression profiles of familial Alzheimer's disease with presenilin 2 mutation patient-specific induced pluripotent stem cells
We established two clones of induced pluripotent stem cells (iPSC) with the presenilin 2 mutation, N...
Molecular characterization of a cryptochrome in Neurospora crassa
Cryptochromes were identified in plants and animals where they function as either photoreceptors or ...
APP/PS1 mice characterization and time progression
RNA samples from the cerebral cortex of APP/PS1 and WT mouse littermates aged 3, 6 and 12 months wer...