Regulation of exon definition and apoptosis by the Ewing's Sarcoma Protein
The Ewing's Sarcoma Protein EWS belongs to the TET family (FUS/TLS, EWS, TAF15) of RNA and DNA bindi...
RNA immunoprecipitation (RIP)-Chip analysis for EWS-bound mRNA
Although EWS/FLI-1 fusion protein is responsible for most Ewing’s sarcoma family tumors (ESFT), th...
Correlation between gene expression responses to FUS, EWS, and TAF15 reduction and the stress granule sequestering capacity
Analysis of differentially expressed genes after siRNA mediated knock-down of the FET-family of prot...
Low-dose actinomycin D preferentially disrupts EWS-FLI1DNA binding
Fusion of the EWS gene to FLI1 produces a fusion oncoprotein that drives an aberrant gene expression...
Regulation of FAS Exon Definition and Apoptosis by the Ewing Sarcoma Protein
The Ewing’s sarcoma protein EWS belongs to the TET family (FUS/TLS, EWS, TAF15) of RNA and DNA bin...
Targeting the EWS/ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma
Ewing sarcomas (ES) are highly malignant, osteolytic bone or soft tissue tumors, which are character...
Oncogenic Fusion Protein EWS-FLI1 is a Network Hub that Regulates Alternative Splicing
The synthesis and processing of mRNA, from transcription to translation initiation, often requires s...
Gene expression profiling of human Ewing sarcoma cells after knockdown of EGR2 or EWSR1-FLI1
To get insight in the functional role of EGR2 for Ewing sarcoma, we performed a transcriptional prof...
RUNX3 Facilitates Growth of Ewing Sarcoma Cells
Ewing sarcoma is an aggressive pediatric small round cell tumor that predominantly occurs in bone. ...
Targeting EWSR1-FLI1 oncogene induced protein kinase C beta abolishes Ewing sarcoma growth in vivo
Identification of druggable targets is a prerequisite for developing targeted therapies against Ewin...
A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion
The identification of subtype-specific translocations has revolutionized diagnostics of sarcoma and ...
Expression profiling of Ewing sarcoma samples
Expression profiling of Ewing sarcoma samples in the frame of the CIT program from the french Ligue ...
Expression profiles of Ewing family of tumors authenticate distinct molecular entities
The concept of Ewing family of tumors (EFT), characterized by FET-ETS fusions, has been recently cha...
EWS siRNA knock-down in HeLa cell line
HeLa cell line was trasfected by a EWS siRNA oligo causing knock-down of EWS or a siRNA scrambled ol...
Cotranscriptional exon skipping in the genotoxic stress response
Pre-mRNA splicing is functionally coupled to transcription, and genotoxic stresses can enhance alter...
Transcription profiling of human NOR1- and EWS/NOR1-overexpressing 293 cells
To examine the differences between NOR1 and its fusion gene product EWS/NOR1, we compared the gene e...
Transcription profiling of human pediatric alveolar (aRMS) and embryonal (eRMS) rhabdomyosarcoma, plus primary pediatric Ewings sarcoma ( EWS)
Affymetrx U95Av2 GeneChip hybridizations, RNA extracted from primary human pediatric alveolar (aRMS)...
Transcription profiling of human mesenchymal progenitor stem cells overexpressing EWS/ETS protein
We have examined the biological effect of EWS/ETS in human MPCs using UET-13 cells that are obtained...
EWS-Fli and LNC regulated genes in comparison to GFP samples
RNA from A673 cells with shRNA-mediated knockdown of GFP (4 libraries), EWS-FLI1 (4 libraries), or ...
pMPC EF vs control 3seq
Ewing sarcoma is a highly aggressive tumor characterized by a translocation between members of the F...