Transcription profiling of human CXCL12- treated T-cells to investigtae CXCL12 mediated T-cell migration via activation of Wnt5A
The chemokine CXCL12 and its receptor CXCR4 play important roles in signaling and migration of T-cel...
CXCL12 Production by Early Mesenchymal Progenitors is Required for Hematopoietic Stem Cell Maintenance
Hematopoietic stem cells (HSCs) primarily reside in the bone marrow where signals generated by strom...
CXCL12 and IGF1 select for cancer cell populations with enhanced bone metastasis ability
CXCL12 and IGF1 confer on cancer cells survival advantage. Src potentiates cancer cells' reponse to ...
Polysome-associated mRNA profiling of cancer cells in response to CXCL12 and IGF1
CXCL12 and IGF1 are key secreting molecules produced by cancer-associated fibroblasts in breast canc...
CXCL12 Stimulation of CXCR4-WHIM Transduced Waldenstrom's Macroglobulinemia cell line BCWM.1
CXCR4 cDNA transcripts were subcloned into plenti-IRES-GFP vectors, and stably transduced using a le...
Apoptotic bodies unleash functional CXCL12 expression through microRNA-126
Apoptosis plays a pivotal role in embryogenesis and postnatal cell homeostasis, involving DNA or sub...
Human Peripheral blood monocytes untreated or treated with CXCL12
Total mRNA expression of CXCL12-treated monocytes was compared with control untreated monocytes Huma...
Transcription profiling of human CD34+ cells and treatment with UTP and CXCL12
Homing and engraftment of hematopoietic stem cells (HSCs) to the bone marrow (BM) involve a complex ...
Function of chemokine (CXC motif) ligand 12 in periodontal ligament fibroblasts
The periodontal ligament (PDL) is one of the connective tissues located between the tooth and bone. ...
CXCL12/CXCR4 signaling mediates niche occupancy and tumor maintenance in T-cell leukemia
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy characterized ...
The niche for extramedullar hematopoiesis in the spleen
Adult hematopoietic stem cells (HSCs) reside primarily in bone marrow. However, hematopoietic stress...
Towards understanding breast cancer mechanisms to metastasize
How organ-specific metastatic traits accumulate in primary tumors remains unknown. We identified a r...
Gene expression pattern in CXCR4+ and CXCR4- subpopulation of breast cancer cells
The goal of this study was to identify signalling molecules downstream of CXCR4 in breast cancer cel...
Gene expression profiles of bone marrow mesenchymal stem cells in pediatric patients with severe aplastic anemia
Pediatric severe aplastic anemia (PSAA) is a rare and life-threatening disease, which has been sugge...
Expression data from Dmp1-Cre targeted and non-targeted Cxcl12-abundant reticular (CAR) cells in mouse bone marrow
In mouse bone marrow, mesenchymal stem cells (MSC) has the potential to form osteocytes, adipocytes ...
Gene expression profile of human ovarian cancer cell lines in vitro
We have previously described how TNF-α, IL-6, CXCR4 and the CXCR4 ligand CXCL12 are expressed by hu...
Human Nephrosclerosis Triggers a Hypoxia-Related Glomerulopathy
Expression data from microdissected glomeruli to examine the role of hypoxia in glomerulosclerosis o...
Transcription profiling of human cord blood-derived mesenchymal stem cells with distinct growth kinetics, differentiation potentials
Phenotypic heterogeneity has been observed among mesenchymal stem/stromal cell (MSC) populations, bu...
Gene expression of SCP-1 cells after incubation with conditioned medium of the breast carcinoma cell line MCF-7
Disseminated tumor cells (DTCs) in the bone marrow can be detected in patients with solid tumors ear...
Gene expression analysis of CD11b+Gr-1+ myeloid cells and epithelial cells purified from Pten KO prostate tumours
Gr-1+ myeloid cells are recruited in prostate conditioanal Pten null tumours (Ptenpc-/-). To identif...