Inhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein- 1 ( MCP- 1/ CCL2)
Monocyte chemoattractant protein 1 (MCP-1/CCL2) is critically involved in directing the migration of...
Chemokine expression in retinal pigment epithelial cells in response to co-culture with activated T Cells
Purpose: To investigate the effects of T cell-derived cytokines on gene and protein expression of ch...
Transcriptome comparison between CCR2+ and CCR2- classical monocytes in SIV-infected Macaca nemestrina
Monocytes have been categorized in three main subpopulations based on CD14 and CD16 surface expressi...
Chemokine Transcripts as Targets of the RNA-Binding Protein HuR in Human Airway Epithelium
HuR is a regulator of mRNA turnover or translation of inflammatory genes through binding to adenylat...
Early CCL2 and CXCL10 chemokine expression correlates with lung pathology in Pandemic H1N1 Influenza A infection
Background: Pandemic H1N1 influenza A is a newly emerging strain of human influenza that is easily t...
Transcript profiling of Lymphangioleiomyomatosis (LAM) nodules in Human Patients
Lymphangioleiomyomatosis (LAM) is characterized by cystic lung destruction caused by smooth, muscle-...
Transcription profiling of human monocytic cell line, THP- 1 cells were stimulated 4 hours with chemokine MIG or CCL2/ MCP- 1
The objective of the study was to discover new functions of chemokine CXCL9/MIG, a cationic chemokin...
Transcription profiling of human neutrophils obtained after exposure endotoxin by bronchoscopic instillation reveals differential gene expression between air space and circulating neutrophils
Although the accumulation of neutrophils in the lungs and airways is common to many inflammatory lun...
Gene expression analysis of CD11b+Gr- 1+ myeloid cells and epithelial cells purified from Pten KO prostate tumours
Gr-1+ myeloid cells are recruited in prostate conditioanal Pten null tumours (Ptenpc-/-). To identif...
IL13 and CCL2 Drive Disease in an Inflammatory Subset of Scleroderma
This SuperSeries is composed of the following subset Series: GSE17914: IL13 and CCL2 Drive Disease i...
Cardiac 12/15-lipoxygenase-induced inflammation is involved in heart failure
To identify a novel target for the treatment of heart failure, we examined gene expression in the fa...
Adipose Tissue MicroRNAs as Regulators of CCL2 Production in Human Obesity
This SuperSeries is composed of the following subset Series: GSE25401: Adipose Tissue MicroRNAs as R...
Long acting progestin-only contraceptives impair endometrial vasculature by inhibiting uterine vascular smooth muscle cell survival
Molecular mechanisms responsible for abnormal endometrial vasculature in women receiving long-actin...
Transcription profiling of human umbilical vein endothelial cells treated with Interferon-gamma (IFN-g), Borrelia burgdorferi or both IFN-g and Borrelia or untreated to investigate immune responses to Lyme disease
Borrelia burgdorferi, the agent of Lyme disease, promotes pro-inflammatory changes in endothelium th...
Transcription profiling of human monocyte derived macrophages reveals induction of dendritic cell-like phenotype in macrophages during foam cell formation
Foam cell formation from monocyte-derived macrophages is a hallmark of atheroscle-rotic lesions. Asp...
Gene expression profiling in heterophils with Salmonella enteritidis challenge using a chicken 44K Agilent microarray
To determine the transcriptional response to Salmonella enterica serovar Enteritidis (SE) infection,...
EWAT transcriptomic analysis in male rat offspring of HF-fed dams treated with GSPE or vehicle during pregnancy and lactation
Objective: Procyanidins are polyphenolic bioactive compounds that exert beneficial effects against o...
Down-regulation as the dominant hippocampal gene expression profile with voluntary resistance wheel running by DNA microarray analysis
Exercise improves brain function enhancing neuronal plasticity and cognitive enhancement. For volunt...
Global Analysis of Glucocorticoid Receptor-Associated Transcripts and Identification of a Target RNA Motif
Posttranscriptional regulation is emerging as a key factor in glucocorticoid (GC)-mediated gene regu...
Potential capacity of aptamers to trigger immune activation in human blood
Target specific short single-stranded DNA (ssDNA) molecules, called aptamers, are auspicious ligands...