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Title Creators Released Date Description
A Novel and Highly Regioselective Route to Construct Methylthio-Substituted Pyridazines from Aryl Methyl Ketones at Room Temperature Wu, Liuming
Yang, Yan
Gao, Meng
Zhang, Dongxue
Shu, Wenming
Zhu, Yanping
Wu, Anxin
04-22-2015 A novel and highly regioselective two-step homocoupling/cyclization procedure from easily available ...
Three-Component Condensation for the Construction of Novel Spirooxindoles Ji, Fei
Sun, Mu
Lv, Mei-Fang
Yi, Wen-Bin
Cai, Chun
04-22-2015 A new route for the synthesis of novel spirooxindoles from isocyanides, dialkyl acetylenedicarboxyla...
Conditions and Edges for the Photochemical Generation of Short-Lived Aryl Cations: A Computational Approach Raviola, Carlotta
Ravelli, Davide
Protti, Stefano
Albini, Angelo
Fagnoni, Maurizio
04-22-2015 A DFT investigation on the conditions required for the photochemical generation of triplet aryl cati...
A Synthesis of 1-Lithiated Glycals and 1-Tributylstannyl Glycals from 1-Phenylsulfinyl Glycals via Sulfoxide-Lithium Ligand Exchange Jarowicki, Krzysztof
Kilner, Colin
Kocienski, Philip J.
Komsta, Zofia
Milne, Jacqueline E.
Wojtasiewicz, Anna
Coombs, Victoria
12-13-2011 1-Lithiated glycals generated by reaction of 1-phenylsulfinyl glycals with either t-BuLi or PhLi are...
Titanium-Catalyzed Cyclopropanation of Boc-Protected Cyanohydrins: A Short Access to Aminocyclopropanecarboxylic Acid Derivatives Pearson-Long, Morwenna S. M.
Beauseigneur, Alice
Karoyan, Philippe
Szymoniak, Jan
Bertus, Philippe
12-13-2011 The preparation of protected 1-aminocyclopropanecarboxylic acid was performed from readily available...
Microwave-Assisted One-Pot Synthesis of Pyrazolo[3,4-b]indoles and New Isoxazolo[5,4-b]indoles via Copper-Catalyzed Intramolecular C-N/C-O Bond Formation Kumar, Arepalli Sateesh
Rao, P. V. Amulya
Nagarajan, Rajagopal
12-13-2011 A facile one-pot, two-step synthesis of highly substituted pyrazolo[3,4-b]indoles and isoxazolo[5,4-...
An Efficient Synthesis of 3-Phosphorylated Benzoxaboroles via the Pudovik Reaction Kamath, Prashantha
Rajan, Ramya
Deshpande, Sudhindra
Montgomery, Mark
Lal, Mukul
03-18-2017 A simple, fast and efficient synthesis of 3-phosphorylated benzoxaboroles using the Pudovik reaction...
Lithium Dibenzylamide, a Simple, Selective and Highly Efficient Catalyst for Isocyanate Cyclotrimerization to Isocyanurate Shi, Jingchao
Guo, Zhiqiang
Wei, Xuehong
Liu, Diansheng
Lappert, Michael F.
12-13-2011 Lithium dibenzylamide catalyzed the rapid and essentially quantitative cyclotrimerization of a varie...
A Practical, Ligand-Free, Palladium-Catalyzed Isocyanide Insertion Reaction for the Construction of Novel Ring-Fused Quinazolinones Ji, Fei
Lv, Mei-Fang
Yi, Wen-Bin
Cai, Chun
04-22-2015 A high-yielding, ligand-free, palladium-catalyzed isocyanide insertion reaction for the synthesis of...
Clean and Efficient Iodination of Thiophene Derivatives Grolleau, Jérémie
Frère, Pierre
Gohier, Frédéric
12-08-2015 Iodination of thiophene derivatives is realized using a simple, fast, and efficient methodology. Iod...
Formal [4+1] Annulation of Cyclopropyl Amides and Water Mediated by Lewis Acid: A Novel Entry to γ-Butyrolactones Zhang, Dingyuan
Zhang, Rui
Liang, Yongjiu
Dong, Dewen
04-22-2015 An efficient one-pot synthesis of substituted γ-butyrolactones from cyclopropyl amides mediated by ...
Palladium-Catalyzed Direct α-Arylation of p-Methoxybenzyl-Protected S,S-Dimethylsulfoximine Sirvent, Juan
Bierer, Donald
Webster, Robert
Lücking, Ulrich
02-16-2017 Sulfoximines have recently gained considerable recognition as an important structural motif in the l...
Synthesis of Sterically Hindered Chiral 1,4-Diols from Different Lignan-Based Backbones Brusentsev, Yury
Hänninen, Mikko
Eklund, Patrik
04-22-2015 Methods for synthetic modifications of the natural dibenzylbutyrolactone lignan hydroxymatairesinol ...
Copper-Catalyzed C–N Cross-Coupling of Substituted 2-Halobenzoates with Secondary Acyclic Amides Wang, Man-Gang
Yu, Hua
Wu, Jun
Shang, Zhi-Cai
04-22-2015 The copper-catalyzed C–N cross-coupling of poorly nucleophilic acyclic secondary amides with steri...
Practical Synthesis of Fluorinated Piperidine Analogues Based on the 2-Azaspiro[3.3]heptane Scaffold Chernykh, Anton
Tkachenko, Anton
Feskov, Illia
Daniliuc, Constantin
Tolmachova, Nataliya
Volochnyuk, Dmitriy
Radchenko, Dmytro
07-08-2016 The synthesis of a set of conformationally restricted fluorinated analogues of piperidine, based on ...
Potassium Carbonate Catalyzed Regioselective Aminohalogenation of β-Nitrostyrenes by Using Benzyl Carbamate/N-Chlorosuccinimide as a New Nitrogen/Chlorine Source Ji, Xiaoyun
Mei, Haibo
Qian, Yu
Han, Jianlin
Li, Guigen
Pan, Yi
12-13-2011 A combination of benzyl carbamate and N-chlorosuccinimide was developed as a new system for aminohal...
Copper-Catalyzed C–N Cross-Coupling of Substituted 2-Halobenzoates with Secondary Acyclic Amides Wang, Man-Gang
Yu, Hua
Wu, Jun
Shang, Zhi-Cai
04-27-2015 The copper-catalyzed C–N cross-coupling of poorly nucleophilic acyclic secondary amides with steri...
Metal-Free Electrocyclization at Ambient Temperature: Synthesis of 1-Arylcarbazoles Samanta, Rajarshi
Kulikov, Katharina
Strohmann, Carsten
Antonchick, Andrey
04-22-2015 An efficient novel protocol for the construction of an hyellazole-inspired compound collection is de...
Process Development of Halaven®: Synthesis of the C14–C35 Fragment via Iterative Nozaki–Hiyama–Kishi Reaction–Williamson Ether Cyclization Austad, Brian
Benayoud, Farid
Calkins, Trevor
Campagna, Silvio
Chase, Charles
Choi, Hyeong-Wook
Christ, William
Costanzo, Robert
Cutter, James
Endo, Atsushi
Fang, Francis
Hu, Yongbo
Lewis, Bryan
Lewis, Michael
McKenna, Shawn
Noland, Thomas
Orr, John
Pesant, Marc
Schnaderbeck, Matthew
Wilkie, Gordon
Abe, Taichi
Asai, Naoki
Asai, Yumi
Kayano, Akio
Kimoto, Yuichi
Komatsu, Yuki
Kubota, Manabu
Kuroda, Hirofumi
Mizuno, Masanori
Nakamura, Taiju
Omae, Takao
Ozeki, Naoki
Suzuki, Taeko
Takigawa, Teiji
Watanabe, Tomohiro
Yoshizawa, Kazuhiro
04-22-2015 Multikilogram manufacturing process of the Halaven® C14–C35 fragment is described. The synthesis ...
Wittig Olefination of Trifluoromethyl Ketones and Allylic Carbonates Mediated by Phosphines Wang, Tong
Shen, Li-Tao
Ye, Song
12-13-2011 The Wittig olefination of trifluromethyl ketones and allylic carbonates mediated by tributylphosphin...