Increased DNA Methylation of Dnmt3b-Targets Impairs Leukemogenesis (expression)
Here, we analyzed global gene expression changes that were associated with over expression of Dnmt3b...
Alternative cleavage and polyadenylation in spermatogenesis coordinates chromatin regulation and post-transcriptional control
Most mammalian genes display alternative cleavage and polyadenylation (APA). Previous studies have i...
Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphoma
Aggressive double and triple hit (DH/TH) DLBCL feature activation of Hsp90 stress pathways. Herein,...
The Histone Methyltransferases MLL1 and DOT1L Cooperate with Meningioma-1 to Induce AML [Mouse Dot1l ko RNA-seq]
Purpose: To characterize transcriptional changes associated with homozygous inactivation of Dot1l or...
MDM33 overexpression suppressor screen
We performed a genome-wide screen for genetic MDM33 interaction partners. Using the opposite approac...
microRNA expression in hematopoietic-associated populations differentiated from induced pluripotent stem cells
In vitro generation of mature neutrophils from human induced pluripotent stem cells (iPSCs) requires...
The Histone Methyltransferases MLL1 and DOT1L Cooperate with Meningioma-1 to Induce AML
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
Transcription profiling of human umbilical vein endothelial cells overexpressing constitutively active FOXO1 to identify FOXO1 target genes
Adenoviral expression of a constitutive active FOXO1 vs. control GFP in human umbilical vein endothe...
Role of ST2 expession in regulatory Tcells on muscle regneration
We describe the effects of Treg ST2 expression on muscle regeneration. We compare regneration from ...
Beta-catenin stabilization of skin fibroblasts causes fibrotic lesions by preventing adipocyte differentiation of the reticular dermis
The Wnt/alpha-catenin pathway plays a central role in epidermal homeostasis and regeneration but how...
Transcriptome analysis upon SIN3 or dKDM5/LID knockdown or both under normal and paraquat induced stress conditions in Drosophila S2 cultured cells
SIN3 the scaffold protein of a histone deacetylase complex interacts with a histone demethylase KDM5...
Gene expression analysis of untreated and NT-shRNA transduced kidney proximal tubular epithelial cells (PTECs) at day 6 and day 16 after transduction, as well as SETD2-shRNA transduced PTECs at day 25 after transduction
Primary kidney PTECs gradually became senescesince day 16, but SETD2 depletion prevented PTECs from ...
Analysis of the role of Micu1 in maintaining functional homeostasis in mouse liver
In this study, we analyzed global liver gene expression in MICU1 knock-down (KD) mice. To generate l...
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. [RNA-Seq]
CNBP is a eukaryote-conserved nucleic-acid binding protein required in mammals for embryonic develop...
Downstream genes regulated by TSHZ2 in MCF-7 cells
To clarify downstream genes regulated by TSHZ2, MCF-7 cells were lentivirally transduced by TSHZ2 an...
Expression data from rat orthotopic bladder cancer
In the development and progression of bladder cancer, there are many genetic changes. We established...
Transcriptional reprogramming and resistance to colonic mucosal injury in PARP1-deficient mice
Poly(ADP-ribose) polymerases (PARPs) synthesize and bind branched polymers of ADP-ribose ...
Gene expression data from lung of mice infected with H5N1 or H1N1 virus
To find the different host response during H5N1 and H1N1 infection, we have employed whole genome mi...
Identification of differentially expressed microRNAs between the fenpropathrin resistant and susceptible strains in Tetranychus cinnabarinus
Purpose: The present study provides the firstly large-scale characterization of miRNAs in Tetranychu...
Cell wall-deficient Mycoplasma hominis represses biofilm formation of uropathogenic Escherichia coli
The features of Mycoplasma in human organ such lung and urinary tract are enigmatic. Here, the role...