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Title: Three-Component Condensation for the Construction of Novel Spirooxindoles      
dateReleased:
04-22-2015
privacy:
information not avaiable
aggregation:
instance of dataset
dateCreated:
03-01-2013
refinement:
curated
ID:
doi:10.4125/PD0036TH
creators:
Ji, Fei
Sun, Mu
Lv, Mei-Fang
Yi, Wen-Bin
Cai, Chun
availability:
available
types:
other
description:
A new route for the synthesis of novel spirooxindoles from isocyanides, dialkyl acetylenedicarboxylates, and N-substituted isatylidene derivatives through [3+2] cycloaddition has been developed. This method has several advantages, such as high regioselectivity, high yields, readily available starting materials, and one-pot operations. The synthetic alkyne-containing spirooxindoles could also be used in the selective synthesis of triazole-containing­ spirocyclic compounds using a copper azide–alkyne cycloaddition­ (CuAAC) reaction.
accessURL: https://doi.org/10.4125/PD0036TH
storedIn:
© Georg Thieme Verlag
qualifier:
not compressed
format:
HTML
accessType:
landing page
authentication:
none
authorization:
none
abbreviation:
Thieme Chemistry
homePage: https://www.thieme.de/
ID:
SCR:SCR_014699
name:
Thieme Chemistry

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