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Title: Practical Synthesis of Fluorinated Piperidine Analogues Based on the 2-Azaspiro[3.3]heptane Scaffold      
dateReleased:
07-08-2016
privacy:
information not avaiable
aggregation:
instance of dataset
dateCreated:
05-04-2016
refinement:
curated
ID:
doi:10.4125/PD0077TH
creators:
Chernykh, Anton
Tkachenko, Anton
Feskov, Illia
Daniliuc, Constantin
Tolmachova, Nataliya
Volochnyuk, Dmitriy
Radchenko, Dmytro
availability:
available
types:
other
description:
The synthesis of a set of conformationally restricted fluorinated analogues of piperidine, based on a 2-azaspiro[3.3]heptane scaffold, is reported. Different pattern of fluorine substitution within the rigid skeleton make the analogues excellent candidates for use in drug design. The overall simplicity of the experimental procedures and the availability of inexpensive starting materials allow for multigram-scale syntheses of the described compounds.
accessURL: https://doi.org/10.4125/PD0077TH
storedIn:
© Georg Thieme Verlag
qualifier:
not compressed
format:
HTML
accessType:
landing page
authentication:
none
authorization:
none
abbreviation:
Thieme Chemistry
homePage: https://www.thieme.de/
ID:
SCR:SCR_014699
name:
Thieme Chemistry

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