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Title: Human Aging and CMV      
description:
Delineate the effect of aging from that of cytomegalovirus (CMV) infection upon relative and absolute changes in blood T cell subsets.
privacy:
not applicable
aggregation:
instance of dataset
availability:
Available for download after registration with ImmPort
refinement:
Curated
keywords:
Observational
Immune Response
acknowledges:
Immunological basis of age-related vulnerability in biodefense and emerging infections SP2 UAz
ID:
SDY736
types:
other
publicationVenue:
J Immunol.
authorsList:
Wertheimer AM(1), Bennett MS, Park B, Uhrlaub JL, Martinez C, Pulko V, Currier NL, Nikolich-Zugich D, Kaye J, Nikolich-Zugich J.
title:
Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans.
publicationVenue:
Nat Immunol.
authorsList:
Pulko V(1,)(2), Davies JS(1,)(2), Martinez C(1,)(2), Lanteri MC(3), Busch MP(3), Diamond MS(4,)(5,)(6), Knox K(1,)(7), Bush EC(8), Sims PA(8,)(9,)(10), Sinari S(11), Billheimer D(11), Haddad EK(12), Murray KO(13,)(14,)(15), Wertheimer AM(1,)(2), Nikolich-??ugich J(1,)(2,)(7).
title:
Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses.
name:
Cellular Phenotype
types:
Flow Cytometry
description:
None
name:
Blood Cell Count with Differential
name:
CMV Screen and Titer
affiliations:
University of Arizona
lastName:
Nikolich-Zugich
roles:
Principal Investigator
firstName:
Janko
email: jnikolich@medadmin.arizona.edu
name:
anti-human CD8b-ECD
roles:
Reagent
name:
anti-human CD11a-FITC
roles:
Reagent
name:
anti-human CD16-PB
roles:
Reagent
name:
anti-human CD3-APC-Cy7
roles:
Reagent
name:
anti-human CD28-Biotin
roles:
Reagent
name:
anti-human CD95-APC
roles:
Reagent
name:
anti-human CCR7 PE-Cy7
roles:
Reagent
name:
anti-human CD4-PerCP-Cy5.5
roles:
Reagent
name:
anti-human CD62L-PE
roles:
Reagent
name:
SA-Qdot 525
roles:
Reagent
name:
T phenotype panel
roles:
Reagent
name:
anti-human CD3-A700
roles:
Reagent
name:
anti-human CD4 APC-eFluor 780
roles:
Reagent
name:
anti-human CD95-PeCy7
roles:
Reagent
name:
anti-human CCR7 PE
roles:
Reagent
name:
anti-human CD57 APC
roles:
Reagent
name:
Live Dead Yellow Fixable Stain
roles:
Reagent
name:
anti-human CD45RA-e450
roles:
Reagent
name:
ALT T phenotype panel
roles:
Reagent
version:
1.0
extraProperties: Link to User Agreement
studyGroups:
CMV positive
CMV negative
selectionCriteria:
Inclusion: ["No history of immune disease (Lupus, RA,HIV), no steroid usage (mild allergy and asthma was acceptable), no history of cancer within 5yrs, stroke, or recent surgery."]
types:
Observational
accessURL: http://www.immport.org/immport-open/public/study/study/displayStudyDetail/SDY736
authorizations:
Registraton with ImmPort required
title:
Human Aging and CMV
accesstypes:
Download tab separated files
identifiers:
SDY736
primary:
true
licenses:
Link to User Agreement
storedIn:
ImmPort
name:
Janko Nikolich-Zugich
identifierSource: http://www.immport.org
identifier:
SDY736
abbreviation:
ImmPort
homePage: http://www.immport.org
ID:
SCR:012804
name:
ImmPort