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Title: The mutation spectrum revealed by paired genome sequences from a lung cancer patient      
availability:
available
aggregation:
instance of dataset
privacy:
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refinement:
curated
ID:
phs000299.v1.p1
description:

Whole genome sequencing was applied to tumor and adjacent normal lung tissue in an individual non-small-cell lung cancer patient. We present an analysis of somatic changes identified throughout the tumor genome, including single-nucleotide variants, copy number variants, and large-scale chromosomal rearrangements. Over 50,000 high-confidence single-nucleotide variants were identified, revealing evidence of substantial smoking-related DNA damage as well as distinct mutational pressures within the tumor resulting in uneven distribution of somatic mutations across the genome.

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storedIn:
EGA
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accessType:
landing page
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authentication:
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primary:
true
accessURL: https://www.ebi.ac.uk/ega/studies/phs000299.v1.p1
format:
JSON
storedIn:
OmicsDI
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not compressed
accessType:
download
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none
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primary:
false
accessURL: www.omicsdi.org/ws/dataset/arrayexpress-repository/phs000299.v1.p1.json
format:
XML
storedIn:
OmicsDI
qualifier:
not compressed
accessType:
download
authorization:
none
authentication:
none
primary:
false
accessURL: http://www.omicsdi.org/ws/dataset/arrayexpress-repository/phs000299.v1.p1.xml
ID:
SCR:014747
name:
Omics Discovery Index
abbreviation:
OmicsDI
homePage: http://www.omicsdi.org/