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Title: Cell Image Library Dataset CIL:12430      
dateReleased:
02-02-2011
description:
The F1F0 ATP synthase is a large protein complex that catalyzes the formation of ATP from ADP and inorganic phosphate using a proton gradient as a source of energy. In eukaryotes, the F1F0 ATP synthase is found in the inner mitochondrial membrane of the mitochondria and the thylakoid membrane of chloroplasts, and is the primary source of ATP in nearly all organisms. ATP synthase is a multisubunit complex composed of a membrane-embedded F0 portion and a catalytic F1 portion that protrudes above the membrane. The F1 portion is made up of a hexamer of alternating alpha and beta subunits arranged around a core gamma subunit. The F0 portion also consists of several different subunit types, named a, b and c. The c-subunit forms a ring which is in close contact with the gamma subunit of F1. As protons move through the F0 portion, the c-ring rotates, causing the rotation of the gamma subunit within the alpha/beta hexamer. This in turn causes the three nucleotide binding sites in F1 to cycle through different conformations, ultimately leading to the synthesis of ATP. This animation illustrates the three conformations that are induced in the alpha and beta subunits by the movement of gamma.
privacy:
not applicable
aggregation:
instance of dataset
ID:
12430
refinement:
curated
availability:
available
types:
image
name:
mitochondrial ATP synthesis coupled proton transport
name:
mitochondrial proton transport
name:
mitochondrial proton-transporting ATP synthase complex
name:
mitochondrial respiratory chain complex V
accessURL: www.cellimagelibrary.org/images/download_jpeg/12430.jpg
storedIn:
Cell Image Library
qualifier:
not compressed
license:
copyright
format:
JPGE
accesstypes:
download
accessType:
download
authentication:
none
authorization:
none
accessURL: http://grackle.crbs.ucsd.edu:8080/OmeroWebService/images/12430.tif
storedIn:
Cell Image Library
qualifier:
not compressed
license:
copyright
format:
OME-TIF
accesstypes:
download
accessType:
download
authentication:
none
authorization:
none
accessURL: http://grackle.crbs.ucsd.edu:8080/OmeroWebService/images/12430.raw
storedIn:
Cell Image Library
qualifier:
compressed
license:
copyright
format:
CSV
accesstypes:
download
accessType:
download
authentication:
none
authorization:
none
abbreviation:
ASCB
homePage: http://ascb.org/
ID:
SCR:010600
name:
American Society for Cell Biology
abbreviation:
CIL
homePage: http://www.cellimagelibrary.org/
ID:
SCR:003510
name:
Cell Image Library

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