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Title: The Persistence of Oral Tolerance Induction to Peanut and Its Immunological Basis (ITN049AD)      
available:
True
dateReleased:
06-02-2011
description:
ITN049AD (LEAP-On) Study is a continuation of the ITN032AD LEAP Study (NCT00329784). Peanut Allergy, a recognized public health concern, is a common and potentially life-threatening food allergy for which there is no treatment. ITN032AD (LEAP) Study evaluated whether early exposure to peanut promotes tolerance and provides protection from developing peanut allergy in children who are allergic to eggs or who have severe eczema. ITN049AD (LEAP-On) Study will evaluate persistent tolerance to peanut by assessing the effect of twelve months of cessation of peanut consumption in LEAP Study participants who consumed peanut and those who avoided peanut over the previous five years.
privacy:
information not available
aggregation:
instance of dataset
ID:
NCT01366846
refinement:
curated
keywords:
Peanut
dateModified:
11-08-2016
availability:
available
types:
clinical trial
ID:
Du Toit G, Sayre PH, Roberts G, Sever ML, Lawson K, Bahnson HT, Brough HA, Santos AF, Harris KM, Radulovic S, Basting M, Turcanu V, Plaut M, Lack G; Immune Tolerance Network LEAP-On Study Team.. Effect of Avoidance on Peanut Allergy after Early Peanut Consumption. N Engl J Med. 2016 Apr 14;374(15):1435-43. doi: 10.1056/NEJMoa1514209.
name:
Other
agent:
Avoidance of peanut
schedulesActivity:
All participants will be assigned to peanut avoidance as per United Kingdom (UK) public health recommendations and will avoid exposure to peanut protein during the study until the last study visit when they will receive the Oral Food Challenge.
funders:
National Institute of Allergy and Infectious Diseases (NIAID)
accessURL: https://clinicaltrials.gov/ct2/show/results/NCT01366846
storedIn:
ClinicalTrial.gov
format:
HTML
accesstypes:
landing page
dateVerified:
20161101
authentication:
none
authorization:
none
creators:
National Institute of Allergy and Infectious Diseases (NIAID)
homepage: https://clinicaltrials.gov
ID:
SCR:002309
name:
ClinicalTrials.gov

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