Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Title: Identification of the Lgr5+ population in human colorectal samples      
keywords:
Transcriptome or Gene expression
ID:
PRJNA359322
description:
Lgr5+ cell population is the stem cell population that fuels intestinal growth in homeostatic conditions. Here, we have labeled with EGFP the Lgr5 expressing population in patient derived organoids, injected them subcutaneously in mice and disaggregated the tumors to sort the EGFP+ population and characterize its gene expression profile. This Lgr5-EGFP population is more proficient in comparison to the negative in propagating tumors both in vitro (assessed by organoid formation) and in vivo (assessed by Tumor initiation experiments) Overall design: Total RNA was collected from the EGFP+ (Lgr5+) population and EGFP- (Lgr5-) population after FACs sorting
accesstypes:
download
landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA359322
authentication:
none
authorization:
none
name:
Homo sapiens
ncbiID:
ncbitax:9606
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject