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Title: Homo sapiens : Homo sapiens Raw sequence reads      
keywords:
raw sequence reads
ID:
PRJNA290342
description:
Somatic retroelement (RE) insertions are typical for the brain where they were proposed to contribute to somatic mosaicism of neuronal genomes. Although the sequencing capacity of high-throughput sequencing technologies is rapidly growing, studies of somatic RE insertions are still limited to small samples, from one to few hundred cells, mainly due to limitations in enrichment protocols. The goal of this study is the development a new approach for identification and quantification of somatic Alu retroelement insertions. This approach is based on selective amplification of the regions flanking retroelement insertions, normalization of this amplicons using Kamchatka Crab nuclease and sequencing normalized amplicons by Illumina HiSeq.
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA290342
authentication:
none
authorization:
none
name:
Homo sapiens
ncbiID:
ncbitax:9606
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject