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Title: Phermone_detection_in_the_main_olfactory_system      
keywords:
Transcriptome or Gene expression
ID:
PRJEB1365
description:
Males and females can show dramatically different stereotyped behavioural responses to similar sensory cues. These are largely innate, suggesting a "hardwired" genetic basis. However the sexual dimorphisms that influence the capacity to detect, transmit, perceive or process sensory information are largely unknown. In rodents, the sensory basis of instinct is mainly through olfaction. We and others have previously identified pheromones that evoke different behavioural responses when detected by either sex. For example, male mice may respond with aggression, while females are attracted to the source of the signal. The precise molecular mechanism of detection for these signals is unknown, but likely occurs via specialized sensory neurons that selectively express olfactory or vomeronasal receptors. A number of avenues of research suggest the sexes may sense the world differently and thus it is possible that there exists molecular dimorphism at the level of signal detection or transduction. Identifying the molecular basis of sex-specific sensory circuits by transcriptome analysis is a critical first step towards tracing these circuits, and understanding the behavioural sexualisation of the brain.
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJEB1365
authentication:
none
authorization:
none
dateReleased:
01-28-2013
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject