biomedical and healthCAre Data Discovery Index Ecosystem
biomedical and healthCAre Data Discovery Index Ecosystem
| Title: | Sex-dependent RNA expression in opossum brain and liver.
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| keywords: |
Transcriptome or Gene expression
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| ID: |
PRJNA157033
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| description: |
To compensate for the increased dosage of X chromosomes in females one of the two X chromosomes is inactivated in eutherian mammals in an Xist-dependent manner. Xist is, however, not found in metatherians. Here we describe long non-coding RNA Rsx (RNA-on-the-silent X) that exhibits properties consistent with a role in X-inactivation in opossum. Rsx is abundantly expressed in females but not males and is transcribed from, and coats, the inactive X chromosome copy. Furthermore, when both X chromosomes are active, Rsx is silenced. We used RNA-Seq to determine exon-intron structure and expression level of Rsx in males and females.
Overall design: RNA sequencing was used to detect and characterize transcripts with strongly biased female expression.
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| accesstypes: |
download
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| landingpage: | http://www.ncbi.nlm.nih.gov/bioproject/PRJNA157033 |
| authentication: |
none
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| authorization: |
none
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| ID: |
pmid:22722828
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| dateReleased: |
06-11-2012
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| name: |
Monodelphis domestica
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| ncbiID: |
ncbitax:13616
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| abbreviation: |
NCBI
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| homePage: | http://www.ncbi.nlm.nih.gov |
| ID: |
SCR:006472
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| name: |
National Center for Biotechnology Information
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| homePage: | http://www.ncbi.nlm.nih.gov/bioproject |
| ID: |
SCR:004801
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| name: |
NCBI BioProject
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