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Title: Sex-dependent RNA expression in opossum brain and liver.      
keywords:
Transcriptome or Gene expression
ID:
PRJNA157033
description:
To compensate for the increased dosage of X chromosomes in females one of the two X chromosomes is inactivated in eutherian mammals in an Xist-dependent manner. Xist is, however, not found in metatherians. Here we describe long non-coding RNA Rsx (RNA-on-the-silent X) that exhibits properties consistent with a role in X-inactivation in opossum. Rsx is abundantly expressed in females but not males and is transcribed from, and coats, the inactive X chromosome copy. Furthermore, when both X chromosomes are active, Rsx is silenced. We used RNA-Seq to determine exon-intron structure and expression level of Rsx in males and females. Overall design: RNA sequencing was used to detect and characterize transcripts with strongly biased female expression.
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA157033
authentication:
none
authorization:
none
ID:
pmid:22722828
dateReleased:
06-11-2012
name:
Monodelphis domestica
ncbiID:
ncbitax:13616
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject
  • U117597141/Medical Research Council/United Kingdom

  • U117597137/Medical Research Council/United Kingdom

  • U117588498/Medical Research Council/United Kingdom

  • R01 HD060858/HD/NICHD NIH HHS/United States

  • ZIA DK052035-05/Intramural NIH HHS/United States

  • Z99 DK999999/Intramural NIH HHS/United States

  • U117581331/Medical Research Council/United Kingdom

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