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Title: Lung biopsies from asthmatics pre- and post- steroid treatment and from healthy control      
keywords:
Transcriptome or Gene expression
ID:
PRJNA129953
description:
To better understand the therapeutic potential of targeting Th2 inflammation in asthma, we performed genome-wide expression profiling of endobronchial biopsies in asthmatics and healthy controls stratified according a previously defined three-gene Th2 signature in bronchial epithelium. The Th2 signature is defined as relatively high expression of POSTN, CLCA1, and SERPINB2. Overall design: Endobronchial biopsies from 27 asthmatics and 13 healthy controls were assayed on expression microarrays. Biopsies were obtained from asthmatics before and one week after treatment with Flovent, an inhaled corticosteroid commonly used to treat asthma.
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA129953
authentication:
none
authorization:
none
ID:
pmid:21187436
dateReleased:
01-18-2011
name:
Homo sapiens
ncbiID:
ncbitax:9606
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject
  • P50 HL056385/HL/NHLBI NIH HHS/United States

  • HL080414/HL/NHLBI NIH HHS/United States

  • R01 HL066564/HL/NHLBI NIH HHS/United States

  • HL09572/HL/NHLBI NIH HHS/United States

  • K23 RR017002/RR/NCRR NIH HHS/United States

  • R01 HL095372/HL/NHLBI NIH HHS/United States

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