Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Title: Microbiota regulate the ability of lung dendritic cells to induce IgA class switch recombination and generate protective GI immune responses      
keywords:
Transcriptome or Gene expression
ID:
PRJNA302059
description:
Analyses of gene expression between CD103+ lung DCs, CD24+ lung DCs and CD64+ lung macrophages in Specific pathogen free (SPF) and germ free (GF) mice. Hypothesis tested was that the IgA class switching function of lung DCs is regulated by genes differentially expressed in GF mice compared to SPF mice. Results obtained provide important insights into the mechanisms of IgA induction by lung DCs Overall design: Total RNA was obtained from flow sorted, lung CD103+ DCs, CD24+ lung DCs and CD64+ lung macrophages from SPF and GF mice
accesstypes:
download
landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA302059
authentication:
none
authorization:
none
ID:
pmid:26712806
name:
Mus musculus
ncbiID:
ncbitax:10090
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject
  • R01 AI57653/AI/NIAID NIH HHS/United States

  • R01 CA190400/CA/NCI NIH HHS/United States

  • UL1 RR024143/RR/NCRR NIH HHS/United States

  • 5UL1RR024143-05/RR/NCRR NIH HHS/United States

  • R18 AI048693/AI/NIAID NIH HHS/United States

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on GitHub.