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Title: Aberrantly activated Gli2-KIF20A axis is crucial for the growth of hepatocellular carcinoma and predicts poor prognosis      
keywords:
Transcriptome or Gene expression
ID:
PRJNA297145
description:
Analysis of gene expression levels in response to inhibition of Hh signaling in hepatocellular cancer cells using a cDNA microarray technique. Microarray analyses revealed that 136 genes were up-regulated and 335 gene were down-regulated after treatment with both cyclopamine (an antagonist of SMO) and GANT61 (a specific, small-molecular molecule inhibitor of Glis). Overall design: HCC-LM3 cells were treated with GANT61 (20 μM for 48 hr), Cyclopamine (20μM for 48 hr) and control vehicle DMSO, respectively.
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA297145
authentication:
none
authorization:
none
ID:
pmid:27036048
name:
Homo sapiens
ncbiID:
ncbitax:9606
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject