Title: | Modulation of mucosal immune responses to Clostridium difficile by peroxisome proliferator-activated receptor γ and microRNA-146b
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keywords: |
Transcriptome or Gene expression
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ID: |
PRJNA170259
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description: |
BACKGROUND: miRNA have been shown to play an important role during immune-mediated diseases such as inflammatory bowel disease. The aim of this study was to assess differential expression of miRNA between uninfected and infected mice with Clostridium difficile strain VPI 10463
RESULTS: MicroRNA (miRNA)-sequencing analysis indicated that miR-146b, miR-1940, and miR-1298 were significantly overexpressed in colons of C. difficile-infected mice
Overall design: Colon of uninfected and C.difficile-infected C57BL6/J WT mice were sampled at day 4 post-infection with Clostridium difficile VPI 10463. The infection dose was 107 cfu/mouse.
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accesstypes: |
download
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landingpage: | http://www.ncbi.nlm.nih.gov/bioproject/PRJNA170259 |
authentication: |
none
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authorization: |
none
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ID: |
pmid:23071818
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dateReleased: |
07-11-2012
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name: |
Mus musculus
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ncbiID: |
ncbitax:10090
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abbreviation: |
NCBI
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homePage: | http://www.ncbi.nlm.nih.gov |
ID: |
SCR:006472
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name: |
National Center for Biotechnology Information
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homePage: | http://www.ncbi.nlm.nih.gov/bioproject |
ID: |
SCR:004801
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name: |
NCBI BioProject
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