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Title: Concerted action of Helios and Ikaros balances the strength of B cell receptor signaling and controls the expression of inositol 5-phosphatase SHIP      
keywords:
Transcriptome or Gene expression
ID:
PRJNA124429
description:
Inositol 5-phosphatase SHIP is differentially expressed in Ikaros and Helios deficient cells. In the absense of Ikaros SHIP is upregulated where as in the absense of Helios it is downregulated. Ikaros binds to the promoter of the SHIP gene. Article provides insight into the mechanisms of action Ikaros employs to regulate BCR signaling. Overall design: Two replicates of Ikaros deficient and wild type DT40 avian B cells.
accesstypes:
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landingpage: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA124429
authentication:
none
authorization:
none
ID:
pmid:20602434
dateReleased:
07-19-2010
name:
Gallus gallus
ncbiID:
ncbitax:9031
abbreviation:
NCBI
homePage: http://www.ncbi.nlm.nih.gov
ID:
SCR:006472
name:
National Center for Biotechnology Information
homePage: http://www.ncbi.nlm.nih.gov/bioproject
ID:
SCR:004801
name:
NCBI BioProject