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Title: Transcription profiling by array of liver from rats treated with furan to study furan-induced cholangiofibrosis      
dateReleased:
04-01-2008
description:
Male Sprague Dawley Crl CD BR rats (190-240g, 6-8 weeks old), were obtained from Charles River, UK. They were given access to R&M No.1 diet and tap water ad libitum. Animals were housed 5/sex in solid bottom cages maintained at 21oC +/- 2oC, 12 h light and 12 h dark. All animals were acclimatised for at least 5 days prior to commencement of the study. Furan (CAS 110-00-9, Sigma-Aldrich Co. Ltd, >99 % pure was prepared in corn oil vehicle on the day of use and stored in sealed brown bottles. Furan was administered orally via gavage in corn oil at 30mg/kg (5 daily doses per week). Animals (n=5) were removed and sampled after 3 months of furan treatment. An off-dose recovery group was included at the 3 month time point (1 month off-dose) to enable assessment of lesion reversibility.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-MEXP-1421
refinement:
raw
keywords:
functional genomics
dateModified:
05-02-2014
creators:
Jonathan M Hitchcock
availability:
available
types:
gene expression
name:
Rattus norvegicus
ID:
A-AFFY-18
name:
Affymetrix GeneChip Rat Genome U34A [RG_U34A]
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MEXP-1421/E-MEXP-1421.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-MEXP-1421/E-MEXP-1421.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress

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