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Title: Concerted action of Helios and Ikaros balances the strength of B cell receptor signaling and controls the expression of inositol 5-phosphatase SHIP      
dateReleased:
07-19-2010
description:
Inositol 5-phosphatase SHIP is differentially expressed in Ikaros and Helios deficient cells. In the absense of Ikaros SHIP is upregulated where as in the absense of Helios it is downregulated. Ikaros binds to the promoter of the SHIP gene. Article provides insight into the mechanisms of action Ikaros employs to regulate BCR signaling. Two replicates of Ikaros deficient and wild type DT40 avian B cells.
privacy:
not applicable
aggregation:
instance of dataset
ID:
E-GEOD-20946
refinement:
raw
alternateIdentifiers:
20946
keywords:
functional genomics
dateModified:
03-27-2012
availability:
available
types:
gene expression
name:
Gallus gallus
ID:
A-GEOD-10224
name:
UTU Chicken BursaEST 37K array
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-20946/E-GEOD-20946.raw.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-20946/E-GEOD-20946.processed.1.zip
storedIn:
ArrayExpress
qualifier:
gzip compressed
format:
TXT
accessType:
download
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE20946
storedIn:
Gene Expression Omnibus
qualifier:
not compressed
format:
HTML
accessType:
landing page
primary:
true
authentication:
none
authorization:
none
abbreviation:
EBI
homePage: http://www.ebi.ac.uk/
ID:
SCR:004727
name:
European Bioinformatics Institute
homePage: https://www.ebi.ac.uk/arrayexpress/
ID:
SCR:002964
name:
ArrayExpress
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