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Title: Untreated 32Dcl3 cell lines expressing oncogenic tyrosine kinases or cells treated with small molecule inhibitors  
description:
Oncogenic tyrosine kinases, such as BCR-ABL, TEL-ABL, TEL-PDGF-beta-R and FLT3-ITD, play a major role in the development of hematopoietic malignancy. They activate many of the same signal transduction pathways. To identify the critical target genes required for transformation in hematopoietic cells, we used a comparative gene expression strategy in which selective small molecules were applied to 32Dcl3 cells that had been transformed to factor-independent growth by these respective oncogenic alleles. Last Updated (by provider): Mar 15 2009 Contributers: Todd R Golub Stefano Monti Stefan Frohling D G Gilliland Benjamin H Lee Andrew Wang Jing Chen Winnie F Tam Lars Bullinger Ting L Gu
privacy:
not applicable
aggregation:
instance of dataset
ID:
1653
refinement:
curated
keywords:
functional genomics
availability:
available
types:
gene expression
ID:
GEO:GSE11794
accessURL: http://www.chibi.ubc.ca/Gemma/expressionExperiment/showExpressionExperiment.html?id=1653
storedIn:
Gemma
qualifier:
filtered
format:
TSV
accessType:
Submit Job
authentication:
none
authorization:
none
accessURL: http://www.chibi.ubc.ca/Gemma/expressionExperiment/showExpressionExperiment.html?id=1653
storedIn:
Gemma
qualifier:
unfiltered
format:
TSV
accessType:
Submit Job
authentication:
none
authorization:
none
accessURL: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE11794
storedIn:
Gene Expression Omnibus
format:
HTML
accessType:
Landing Page
primary:
true
authentication:
none
authorization:
none
abbreviation:
UBC
homePage: http://www.ubc.ca/
ID:
SCR:011614
name:
University of British Columbia
homePage: http://www.chibi.ubc.ca/Gemma
ID:
SCR:008007
name:
Gemma

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