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Title: MLN8054 KINOMEscan      
creators:
Nathanael Gray
Qingsong Liu
aggregation:
instance of dataset
availability:
available
privacy:
not applicable
refinement:
curated
types:
Binding
Protein binding profile
dateReleased:
07-15-2011
dateModified:
10-06-2015
version:
1551623648393035776
ID:
LDS-1028
name:
Small molecule metabolic process
name:
qPCR
name:
Nathanael Gray
Qingsong Liu
name:
MLN-8054
name:
KINOMEscan kinase-small molecule binding assay
name:
AAK1 ABL1(E255K)-phosphorylated ABL1(F317I)-nonphosphorylated ABL1(F317I)-phosphorylated ABL1(F317L)-nonphosphorylated ABL1(F317L)-phosphorylated ABL1(H396P)-nonphosphorylated ABL1(H396P)-phosphorylated ABL1(M351T)-phosphorylated ABL1(Q252H)-nonphosphorylated ABL1(Q252H)-phosphorylated ABL1(T315I)-nonphosphorylated ABL1(T315I)-phosphorylated ABL1(Y253F)-phosphorylated ABL1-nonphosphorylated ABL1-phosphorylated ABL2 ACVR1 ACVR1B ACVR2A ACVR2B ACVRL1 ADCK4 AKT1 AKT2 AKT3 ALK AMPK-alpha1 AMPK-alpha2 ANKK1 AURKA AURKB AURKC AXL BIKE BLK BMPR1A BMPR1B BMPR2 BMX BRAF BRAF(V600E) BRSK1 BRSK2 BTK CAMK1 CAMK1D CAMK1G CAMK2A CAMK2B CAMK2G CAMKK2 GAK CASK CDC2L2 CDK2 CDK3 CDK4-cyclinD1 CDK4-cyclinD3 CDK5 CDK7 CDK8 CDK9 CDKL1 CDKL2 CDKL3 CDKL5 CHEK1 CIT CLK1 CLK2 CLK3 CLK4 CSF1R CSK CSNK1A1 CSNK1A1L CSNK1D CSNK1E CSNK1G3 CSNK2A1 CSNK2A2 CTK DAPK1 DAPK2 DAPK3 DCAMKL2 DCAMKL3 DDR1 DDR2 DMPK DMPK2 DRAK1 DRAK2 DYRK1A DYRK1B DYRK2 EGFR EGFR(E746-A750del) EGFR(G719C) EGFR(G719S) EGFR(L747-E749del, A750P) EGFR(L747-S752del, P753S) EGFR(L747-T751del,Sins) EGFR(L858R) EGFR(L858R,T790M) EGFR(L861Q) EGFR(S752-I759del) EGFR(T790M) EIF2AK1 EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA6 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 ERBB2 ERBB3 ERBB4 ERK3 ERK4 ERK5 ERK8 ERN1 FER FES FGFR1 FGFR2 FGFR3 FGFR3(G697C) FGFR4 FGR FLT3 FLT3(D835H) FLT3(D835Y) FLT3(ITD) FLT3(K663Q) FLT3(N841I) FLT3(R834Q) FLT4 FRK FYN GCN2(Kin.Dom.2,S808G) GRK1 GRK4 GRK7 GSK3A GSK3B HCK HIPK1 HIPK2 HIPK3 HIPK4 HUNK ICK IGF1R INSR INSRR IRAK1 IRAK3 IRAK4 ITK JAK1(JH1domain-catalytic) JAK1(JH2domain-pseudokinase) JAK2(JH1domain-catalytic) JAK3(JH1domain-catalytic) JNK1 JNK3 KIT KIT(A829P) KIT(D816H) KIT(D816V) KIT(L576P) KIT(V559D) KIT(V559D,T670I) KIT(V559D,V654A) LATS1 LATS2 LCK LIMK1 LIMK2 LKB1 LOK LRRK2 LRRK2(G2019S) LTK LYN MAK MAP3K1 MAP3K15 MAP3K3 MAP3K4 MAP4K2 MAP4K4 MAP4K5 MAPKAPK2 MAPKAPK5 MARK1 MARK2 MARK3 MARK4 MAST1 MELK MERTK MET NEK5 MET(M1250T) MET(Y1235D) MINK MKNK1 MKNK2 MLCK MLK1 MLK2 MLK3 MRCKA MRCKB MST1 MST1R MST2 MST3 MST4 MTOR MUSK MYLK MYLK2 MYLK4 MYO3A MYO3B NDR1 NDR2 NEK1 NEK11 NEK2 NEK3 NEK4 CDK16 NEK6 NEK7 NEK9 NLK OSR1 PAK1 PAK2 PAK3 PAK4 PAK6 PAK7 PDPK1 PHKG1 PHKG2 PIK3C2B PIK3C2G PIK3CA PIK3CA(C420R) PIK3CA(E542K) PIK3CA(E545A) PIK3CA(E545K) PIK3CA(H1047L) PIK3CA(H1047Y) PIK3CA(I800L) PIK3CA(M1043I) PIK3CA(Q546K) PIK3CB PIK3CD PIK3CG PIK4CB PIM1 PIM2 PIM3 PIP5K1A PIP5K1C PIP5K2B PKAC-alpha PKAC-beta PKMYT1 PKN1 PKN2 PKNB(M.tuberculosis) PLK1 PLK2 PLK3 PLK4 PRKR PRKX PRP4 RAF1 RET YSK4 RET(M918T) RET(V804L) RET(V804M) RIOK1 RIOK2 RIOK3 RIPK1 RIPK2 RIPK4 ROCK1 M3K13 ROCK2 ROS1 RPS6KA4(Kin.Dom.1-N-terminal) RPS6KA4(Kin.Dom.2-C-terminal) RPS6KA5(Kin.Dom.1-N-terminal) RPS6KA5(Kin.Dom.2-C-terminal) ZAP70 RSK1(Kin.Dom.1-N-terminal) RSK1(Kin.Dom.2-C-terminal) RSK2(Kin.Dom.1-N-terminal) RSK3(Kin.Dom.1-N-terminal) M3K2 RSK3(Kin.Dom.2-C-terminal) RSK4(Kin.Dom.1-N-terminal) RSK4(Kin.Dom.2-C-terminal) S6K1 SBK1 SgK110 SGK3 SLK SNARK SNRK SRC SRMS SRPK1 SRPK2 SRPK3 STK16 STK33 STK35 STK36 STK39 SYK TAK1 TAOK1 TAOK2 TAOK3 TBK1 TEC TESK1 M4K3 TGFBR1 TGFBR2 TIE1 TIE2 TLK1 TLK2 TNIK TNK1 TNK2 TNNI3K TRKA TRKB TRKC TRPM6 TTK TXK TYK2(JH1domain-catalytic) TYK2(JH2domain-pseudokinase) TYRO3 ULK1 ULK2 ULK3 VRK2 WEE1 WEE2 YANK1 YANK2 YANK3 YES YSK1 KPCD2 ADCK3 NUAK1 M3K5 M3K6 PTK6 KCC2D KCC4 KKCC1 CHK2 KC1G1 KC1G2 M3K12 FAK1 VGFR1 M4K1 IKKA IKKB DCLK1 IKKE MK09 MP2K1 MP2K2 MP2K3 MP2K4 MP2K5 MP2K6 MP2K7 NIM1 MK14 MK11 MK13 MK12 PGFRA PGFRB CDK15 CDK14 PI42C KPCD KPCE KPCL KPCI KPCT KPCD1 KPCD3 KGP1 KGP2 FAK2 SIK3 SIK1 SIK2 TSSK1 VGFR2 MLTK CDC2L1 CDC2L5 CDK11 MK03 MK01 PCTK2 PCTK3 PFCDPK1(P.falciparum) PFPK5(P.falciparum) RIPK5
projectName:
LINCS phase 1
storedIn:
LINCS
authorization:
none
authentication:
none
format:
information not available
accessURL: http://lincsportal.ccs.miami.edu/dcic/api/download?path=LINCS_Data/HMS_LINCS&file=LDS-1028.tar.gz
accesstypes:
download
qualifier:
gzip compressed
abbreviation:
HMS_LINCS
name:
HMS LINCS (Harvard Medical School)
homePage: http://www.lincsproject.org
name:
Library of Integrated Network-Based Cellular Signatures
ID:
SCR:006454

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