biomedical and healthCAre Data Discovery Index Ecosystem
biomedical and healthCAre Data Discovery Index Ecosystem
| Title: | Structure of AMPK bound to activator
|
| dateReleased: |
05-17-2017
|
| creators: |
Cokorinos, E.C.
Delmore, J.
Reyes, A.R.
Albuquerque, B.
Kjbsted, R.
Jrgensen, N.O.
Tran, J.L.
Jatkar, A.
Cialdea, K.
Esquejo, R.M.
Meissen, J.
Calabrese, M.F.
Cordes, J.
Moccia, R.
Tess, D.
Salatto, C.T.
Coskran, T.M.
Opsahl, A.C.
Flynn, D.
Blatnik, M.
Li, W.
Kindt, E.
Foretz, M.
Viollet, B.
Ward, J.
Kurumbail, R.G.
Kalgutkar, A.S.
Wojtaszewski, J.F.P.
Cameron, K.O.
Miller, R.A.
|
| description: |
5'-AMP-activated protein kinase catalytic subunit alpha-1,5'-AMP-activated protein kinase catalytic subunit alpha-1 (E.C.2.7.11.1,2.7.11.1,2.7.11.27,2.7.11.31,2.7.11.26), 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1
|
| privacy: |
not applicable
|
| aggregation: |
instance of dataset
|
| ID: |
PDB:5UFU
|
| refinement: |
curated
|
| keywords: |
TRANSFERASE/ACTIVATOR
Kinase
AMPK
activator
allostery
TRANSFERASE-ACTIVATOR complex
|
| dateCreated: |
01-05-2017
|
| availability: |
available
|
| types: |
structure
|
| name: |
Rattus norvegicus
|
| ID: |
ncbitax:10116
|
| name: |
Mus musculus
|
| ID: |
ncbitax:10090
|
| name: |
Rattus norvegicus
|
| ID: |
ncbitax:10116
|
| name: |
Rattus norvegicus
|
| ID: |
ncbitax:10116
|
| name: |
Escherichia coli
|
| ID: |
ncbitax:562
|
| name: |
Escherichia coli
|
| ID: |
ncbitax:562
|
| name: |
Escherichia coli
|
| ID: |
ncbitax:562
|
| name: |
Escherichia coli
|
| ID: |
ncbitax:562
|
| authors: |
Cokorinos, E.C.
Delmore, J.
Reyes, A.R.
Albuquerque, B.
Kjbsted, R.
Jrgensen, N.O.
Tran, J.L.
Jatkar, A.
Cialdea, K.
Esquejo, R.M.
Meissen, J.
Calabrese, M.F.
Cordes, J.
Moccia, R.
Tess, D.
Salatto, C.T.
Coskran, T.M.
Opsahl, A.C.
Flynn, D.
Blatnik, M.
Li, W.
Kindt, E.
Foretz, M.
Viollet, B.
Ward, J.
Kurumbail, R.G.
Kalgutkar, A.S.
Wojtaszewski, J.F.P.
Cameron, K.O.
Miller, R.A.
|
| alternateID: |
doi:10.1016/j.cmet.2017.04.010
|
| year: |
2017
|
| ID: | pmid:28467931 |
| title: |
Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice.
|
| formula: |
C23 H23 Cl N2 O5
|
| name: |
1,4:3,6-dianhydro-2-O-(6-chloro-5-{4-[1-(hydroxymethyl)cyclopropyl]phenyl}-1H-benzimidazol-2-yl)-D-mannitol
|
| roles: |
chemical component
|
| formula: |
C10 H15 N5 O10 P2
|
| name: |
ADENOSINE-5'-DIPHOSPHATE
|
| roles: |
chemical component
|
| formula: |
C3 H7 N O2
|
| name: |
ALANINE
|
| roles: |
chemical component
|
| formula: |
C10 H14 N5 O7 P
|
| name: |
ADENOSINE MONOPHOSPHATE
|
| roles: |
chemical component
|
| formula: |
C6 H15 N4 O2 1
|
| name: |
ARGININE
|
| roles: |
chemical component
|
| formula: |
C4 H8 N2 O3
|
| name: |
ASPARAGINE
|
| roles: |
chemical component
|
| formula: |
C4 H7 N O4
|
| name: |
ASPARTIC ACID
|
| roles: |
chemical component
|
| formula: |
Cl -1
|
| name: |
CHLORIDE ION
|
| roles: |
chemical component
|
| formula: |
C3 H7 N O2 S
|
| name: |
CYSTEINE
|
| roles: |
chemical component
|
| formula: |
C5 H10 N2 O3
|
| name: |
GLUTAMINE
|
| roles: |
chemical component
|
| formula: |
C5 H9 N O4
|
| name: |
GLUTAMIC ACID
|
| roles: |
chemical component
|
| formula: |
C2 H5 N O2
|
| name: |
GLYCINE
|
| roles: |
chemical component
|
| formula: |
C6 H10 N3 O2 1
|
| name: |
HISTIDINE
|
| roles: |
chemical component
|
| formula: |
C6 H13 N O2
|
| name: |
ISOLEUCINE
|
| roles: |
chemical component
|
| formula: |
C6 H13 N O2
|
| name: |
LEUCINE
|
| roles: |
chemical component
|
| formula: |
C6 H15 N2 O2 1
|
| name: |
LYSINE
|
| roles: |
chemical component
|
| formula: |
C5 H11 N O2 S
|
| name: |
METHIONINE
|
| roles: |
chemical component
|
| formula: |
C9 H11 N O2
|
| name: |
PHENYLALANINE
|
| roles: |
chemical component
|
| formula: |
C5 H9 N O2
|
| name: |
PROLINE
|
| roles: |
chemical component
|
| formula: |
C3 H7 N O3
|
| name: |
SERINE
|
| roles: |
chemical component
|
| formula: |
O4 S -2
|
| name: |
SULFATE ION
|
| roles: |
chemical component
|
| formula: |
C28 H26 N4 O3
|
| name: |
STAUROSPORINE
|
| roles: |
chemical component
|
| formula: |
C4 H9 N O3
|
| name: |
THREONINE
|
| roles: |
chemical component
|
| formula: |
C4 H10 N O6 P
|
| name: |
PHOSPHOTHREONINE
|
| roles: |
chemical component
|
| formula: |
C11 H12 N2 O2
|
| name: |
TRYPTOPHAN
|
| roles: |
chemical component
|
| formula: |
C9 H11 N O3
|
| name: |
TYROSINE
|
| roles: |
chemical component
|
| formula: |
C5 H11 N O2
|
| name: |
VALINE
|
| roles: |
chemical component
|
| name: |
Prkaa1, Ampk1
|
| name: |
Prkaa1
|
| name: |
Prkab1
|
| name: |
Prkag1
|
| name: |
X-RAY DIFFRACTION
|
| ID: |
pdb:5UFU
|
| ID: |
wwpdb:D_1000225795
|
| accessURL: | https://files.rcsb.org/download/5UFU.xml.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
PDBML/XML
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | https://files.rcsb.org/download/5UFU.pdb.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
PDB Format
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | https://files.rcsb.org/download/5UFU.cif.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
PDBx/mmCIF
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | http://www.rcsb.org/pdb/download/downloadFile.do?fileFormat=FASTA&compression=NO&structureId=5UFU |
| storedIn: |
Protein Data Bank
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
FASTA
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | https://files.rcsb.org/download/5UFU-sf.cif.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
CIF
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | https://files.rcsb.org/download/5UFU.pdb1.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
PDB Format (A)
|
| accessType: |
download
|
| authentication: |
none
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| authorization: |
none
|
| accessURL: | http://www.rcsb.org/pdb/explore/jmol.do?structureId=5UFU&bionumber=1 |
| storedIn: |
Protein Data Bank
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
JSmol
|
| accessType: |
view
|
| authentication: |
none
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| authorization: |
none
|
| abbreviation: |
wwPDB
|
| homePage: | http://www.wwpdb.org |
| ID: |
SCR:006555
|
| name: |
Worldwide Protein Data Bank
|
| abbreviation: |
PDB
|
| homePage: | http://www.rcsb.org/pdb/ |
| ID: |
SCR:012820
|
| name: |
Protein Data Bank
|
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