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Title: Crystal structure of activated G alpha Q bound to its effector phospholipase C beta 3      
description:
Guanine nucleotide-binding protein G(q) subunit alpha, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 (E.C.3.1.4.11)
privacy:
not applicable
aggregation:
instance of dataset
ID:
PDB:3OHM
refinement:
curated
keywords:
signaling protein / HYDROLASE
PH domain
EF hand
TIM barrel
C2 domain
GTPase
lipase
calcium binding
GTP binding
ALF4 binding
signaling protein - HYDROLASE complex
creators:
Waldo, G.L.
Ricks, T.K.
Hicks, S.N.
Cheever, M.L.
Kawano, T.
Tsuboi, K.
Wang, X.
Montell, C.
Kozasa, T.
Sondek, J.
Harden, T.K.
availability:
available
types:
structure
name:
Mus musculus
ID:
ncbitax:10090
name:
Homo sapiens
ID:
ncbitax:9606
name:
Spodoptera frugiperda
ID:
ncbitax:7108
name:
Spodoptera frugiperda
ID:
ncbitax:7108
authors:
Waldo, G.L.
Ricks, T.K.
Hicks, S.N.
Cheever, M.L.
Kawano, T.
Tsuboi, K.
Wang, X.
Montell, C.
Kozasa, T.
Sondek, J.
Harden, T.K.
alternateID:
doi:10.1126/science.1193438
year:
2010
ID: pmid:20966218
title:
Kinetic Scaffolding Mediated by a Phospholipase C-{beta} and Gq Signaling Complex.
formula:
C6 H15 N4 O2 1
name:
ARGININE
roles:
chemical component
formula:
C5 H9 N O4
name:
GLUTAMIC ACID
roles:
chemical component
formula:
C6 H13 N O2
name:
LEUCINE
roles:
chemical component
formula:
C6 H15 N2 O2 1
name:
LYSINE
roles:
chemical component
formula:
C2 H5 N O2
name:
GLYCINE
roles:
chemical component
formula:
C4 H9 N O3
name:
THREONINE
roles:
chemical component
formula:
C3 H7 N O3
name:
SERINE
roles:
chemical component
formula:
C9 H11 N O2
name:
PHENYLALANINE
roles:
chemical component
formula:
C6 H13 N O2
name:
ISOLEUCINE
roles:
chemical component
formula:
C5 H10 N2 O3
name:
GLUTAMINE
roles:
chemical component
formula:
C5 H11 N O2 S
name:
METHIONINE
roles:
chemical component
formula:
C6 H10 N3 O2 1
name:
HISTIDINE
roles:
chemical component
formula:
C9 H11 N O3
name:
TYROSINE
roles:
chemical component
formula:
C4 H7 N O4
name:
ASPARTIC ACID
roles:
chemical component
formula:
C5 H11 N O2
name:
VALINE
roles:
chemical component
formula:
C4 H8 N2 O3
name:
ASPARAGINE
roles:
chemical component
formula:
C3 H7 N O2
name:
ALANINE
roles:
chemical component
formula:
C5 H9 N O2
name:
PROLINE
roles:
chemical component
formula:
C11 H12 N2 O2
name:
TRYPTOPHAN
roles:
chemical component
formula:
C3 H7 N O2 S
name:
CYSTEINE
roles:
chemical component
formula:
C10 H15 N5 O11 P2
name:
GUANOSINE-5'-DIPHOSPHATE
roles:
chemical component
formula:
AL F4 -1
name:
TETRAFLUOROALUMINATE ION
roles:
chemical component
formula:
MG 2
name:
MAGNESIUM ION
roles:
chemical component
formula:
CA 2
name:
CALCIUM ION
roles:
chemical component
formula:
C2 H3 O2 -1
name:
ACETATE ION
roles:
chemical component
formula:
H2 O
name:
WATER
roles:
chemical component
name:
Gnaq
name:
PLC BETA 3, PLCB3
name:
X-RAY DIFFRACTION
ID:
pdb:3OHM
ID:
rcsb:RCSB061126
accessURL: https://files.rcsb.org/download/3OHM.xml.gz
storedIn:
Protein Data Bank
qualifier:
gzip compressed
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
PDBML/XML
accessType:
download
authentication:
none
authorization:
none
accessURL: https://files.rcsb.org/download/3OHM.pdb.gz
storedIn:
Protein Data Bank
qualifier:
gzip compressed
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
PDB Format
accessType:
download
authentication:
none
authorization:
none
accessURL: https://files.rcsb.org/download/3OHM.cif.gz
storedIn:
Protein Data Bank
qualifier:
gzip compressed
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
PDBx/mmCIF
accessType:
download
authentication:
none
authorization:
none
accessURL: http://www.rcsb.org/pdb/download/downloadFile.do?fileFormat=FASTA&compression=NO&structureId=3OHM
storedIn:
Protein Data Bank
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
FASTA
accessType:
download
authentication:
none
authorization:
none
accessURL: https://files.rcsb.org/download/3OHM-sf.cif.gz
storedIn:
Protein Data Bank
qualifier:
gzip compressed
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
CIF
accessType:
download
authentication:
none
authorization:
none
accessURL: https://files.rcsb.org/download/3OHM.pdb1.gz
storedIn:
Protein Data Bank
qualifier:
gzip compressed
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
PDB Format (A)
accessType:
download
authentication:
none
authorization:
none
accessURL: http://www.rcsb.org/pdb/explore/jmol.do?structureId=3OHM&bionumber=1
storedIn:
Protein Data Bank
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
JSmol
accessType:
view
authentication:
none
authorization:
none
abbreviation:
wwPDB
homePage: http://www.wwpdb.org
ID:
SCR:006555
name:
Worldwide Protein Data Bank
abbreviation:
PDB
homePage: http://www.rcsb.org/pdb/
ID:
SCR:012820
name:
Protein Data Bank
  • P01 GM065533/GM/NIGMS NIH HHS/United States

  • GM61454/GM/NIGMS NIH HHS/United States

  • R01 GM038213/GM/NIGMS NIH HHS/United States

  • P30 CA016086/CA/NCI NIH HHS/United States

  • R01 GM057391/GM/NIGMS NIH HHS/United States

  • R01 GM074001/GM/NIGMS NIH HHS/United States

  • R01 GM062299/GM/NIGMS NIH HHS/United States

  • R01 EY010852/EY/NEI NIH HHS/United States

  • R01 GM057391-13/GM/NIGMS NIH HHS/United States

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