biomedical and healthCAre Data Discovery Index Ecosystem
biomedical and healthCAre Data Discovery Index Ecosystem
| Title: | Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by (A611V, F608S) mutations at 1.55A
|
| description: |
Glucocorticoid receptor, Nuclear receptor coactivator 2 peptide
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| privacy: |
not applicable
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| aggregation: |
instance of dataset
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| ID: |
PDB:3MNO
|
| refinement: |
curated
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| keywords: |
HORMONE RECEPTOR
protein-ligand complex
steroid nuclear receptor
mouse GR
agonist
co-activator
|
| creators: |
Seitz, T.
Thoma, R.
Schoch, G.A.
Stihle, M.
Benz, J.
D'Arcy, B.
Wiget, A.
Ruf, A.
Hennig, M.
Sterner, R.
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| availability: |
available
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| types: |
structure
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| name: |
Mus musculus
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| ID: |
ncbitax:10090
|
| name: |
Escherichia coli
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| ID: |
ncbitax:562
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| authors: |
Seitz, T.
Thoma, R.
Schoch, G.A.
Stihle, M.
Benz, J.
D'Arcy, B.
Wiget, A.
Ruf, A.
Hennig, M.
Sterner, R.
|
| alternateID: |
doi:10.1016/j.jmb.2010.08.048
|
| year: |
2010
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| ID: | pmid:20850457 |
| title: |
Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening.
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| formula: |
C5 H11 N O2 S
|
| name: |
METHIONINE
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| roles: |
chemical component
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| formula: |
C5 H11 N O2
|
| name: |
VALINE
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| roles: |
chemical component
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| formula: |
C5 H9 N O2
|
| name: |
PROLINE
|
| roles: |
chemical component
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| formula: |
C3 H7 N O2
|
| name: |
ALANINE
|
| roles: |
chemical component
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| formula: |
C6 H13 N O2
|
| name: |
LEUCINE
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| roles: |
chemical component
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| formula: |
C5 H10 N2 O3
|
| name: |
GLUTAMINE
|
| roles: |
chemical component
|
| formula: |
C4 H9 N O3
|
| name: |
THREONINE
|
| roles: |
chemical component
|
| formula: |
C3 H7 N O3
|
| name: |
SERINE
|
| roles: |
chemical component
|
| formula: |
C5 H9 N O4
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| name: |
GLUTAMIC ACID
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| roles: |
chemical component
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| formula: |
C6 H13 N O2
|
| name: |
ISOLEUCINE
|
| roles: |
chemical component
|
| formula: |
C9 H11 N O3
|
| name: |
TYROSINE
|
| roles: |
chemical component
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| formula: |
C2 H5 N O2
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| name: |
GLYCINE
|
| roles: |
chemical component
|
| formula: |
C4 H7 N O4
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| name: |
ASPARTIC ACID
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| roles: |
chemical component
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| formula: |
C11 H12 N2 O2
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| name: |
TRYPTOPHAN
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| roles: |
chemical component
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| formula: |
C6 H15 N4 O2 1
|
| name: |
ARGININE
|
| roles: |
chemical component
|
| formula: |
C4 H8 N2 O3
|
| name: |
ASPARAGINE
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| roles: |
chemical component
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| formula: |
C6 H15 N2 O2 1
|
| name: |
LYSINE
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| roles: |
chemical component
|
| formula: |
C9 H11 N O2
|
| name: |
PHENYLALANINE
|
| roles: |
chemical component
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| formula: |
C6 H10 N3 O2 1
|
| name: |
HISTIDINE
|
| roles: |
chemical component
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| formula: |
C3 H7 N O2 S
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| name: |
CYSTEINE
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| roles: |
chemical component
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| formula: |
C3 H8 O3
|
| name: |
GLYCEROL
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| roles: |
chemical component
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| formula: |
C22 H29 F O5
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| name: |
DEXAMETHASONE
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| roles: |
chemical component
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| formula: |
C N S -1
|
| name: |
THIOCYANATE ION
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| roles: |
chemical component
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| formula: |
H2 O
|
| name: |
WATER
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| roles: |
chemical component
|
| name: |
Nr3c1, Grl, Grl1
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| name: |
X-RAY DIFFRACTION
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| ID: |
pdb:3MNO
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| ID: |
rcsb:RCSB058772
|
| accessURL: | https://files.rcsb.org/download/3MNO.xml.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
PDBML/XML
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | https://files.rcsb.org/download/3MNO.pdb.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
PDB Format
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | https://files.rcsb.org/download/3MNO.cif.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
PDBx/mmCIF
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | http://www.rcsb.org/pdb/download/downloadFile.do?fileFormat=FASTA&compression=NO&structureId=3MNO |
| storedIn: |
Protein Data Bank
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
FASTA
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | https://files.rcsb.org/download/3MNO-sf.cif.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
CIF
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | https://files.rcsb.org/download/3MNO.pdb1.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
PDB Format (A)
|
| accessType: |
download
|
| authentication: |
none
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| authorization: |
none
|
| accessURL: | http://www.rcsb.org/pdb/explore/jmol.do?structureId=3MNO&bionumber=1 |
| storedIn: |
Protein Data Bank
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
JSmol
|
| accessType: |
view
|
| authentication: |
none
|
| authorization: |
none
|
| abbreviation: |
wwPDB
|
| homePage: | http://www.wwpdb.org |
| ID: |
SCR:006555
|
| name: |
Worldwide Protein Data Bank
|
| abbreviation: |
PDB
|
| homePage: | http://www.rcsb.org/pdb/ |
| ID: |
SCR:012820
|
| name: |
Protein Data Bank
|
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