description: |
Glucocorticoid receptor, Nuclear receptor coactivator 1 (E.C.2.3.1.48)
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privacy: |
not applicable
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aggregation: |
instance of dataset
|
ID: |
PDB:3BQD
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refinement: |
curated
|
keywords: |
PROTEIN BINDING
GLUCOCORTICOID RECEPTOR
deacylcortivazol
SRC1
nuclear receptor coactivator 1 isoform 1
DIMER INTERFACE
HORMONE BINDING POCKET
CHARGE CLAMP
COACTIVATOR
Alternative initiation
Chromatin regulator
Disease mutation
DNA-binding
Lipid-binding
Metal-binding
Nucleus
Phosphoprotein
Pseudohermaphroditism
Steroid-binding
Transcription
Transcription regulation
Zinc-finger
Acyltransferase
Proto-oncogene
Transferase
|
creators: |
Suino-Powell, K.
Xu, Y.
Zhang, C.
Tao, Y.G.
Tolbert, W.D.
Simons, S.S.
Xu, H.E.
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availability: |
available
|
types: |
structure
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strain: |
BL21(DE3)
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ID: |
ncbitax:9606
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name: |
Homo sapiens
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species: |
Escherichia coli
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name: |
Escherichia coli BL21(DE3)
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ID: |
ncbitax:469008
|
authors: |
Suino-Powell, K.
Xu, Y.
Zhang, C.
Tao, Y.G.
Tolbert, W.D.
Simons, S.S.
Xu, H.E.
|
alternateID: |
doi:10.1128/MCB.01541-07
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year: |
2008
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ID: | pmid:18160712 |
title: |
Doubling the size of the glucocorticoid receptor ligand binding pocket by deacylcortivazol.
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formula: |
C6 H13 N O2
|
name: |
LEUCINE
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roles: |
chemical component
|
formula: |
C5 H9 N O2
|
name: |
PROLINE
|
roles: |
chemical component
|
formula: |
C5 H10 N2 O3
|
name: |
GLUTAMINE
|
roles: |
chemical component
|
formula: |
C4 H9 N O3
|
name: |
THREONINE
|
roles: |
chemical component
|
formula: |
C5 H11 N O2
|
name: |
VALINE
|
roles: |
chemical component
|
formula: |
C3 H7 N O3
|
name: |
SERINE
|
roles: |
chemical component
|
formula: |
C5 H9 N O4
|
name: |
GLUTAMIC ACID
|
roles: |
chemical component
|
formula: |
C6 H13 N O2
|
name: |
ISOLEUCINE
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roles: |
chemical component
|
formula: |
C9 H11 N O3
|
name: |
TYROSINE
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roles: |
chemical component
|
formula: |
C3 H7 N O2
|
name: |
ALANINE
|
roles: |
chemical component
|
formula: |
C2 H5 N O2
|
name: |
GLYCINE
|
roles: |
chemical component
|
formula: |
C4 H7 N O4
|
name: |
ASPARTIC ACID
|
roles: |
chemical component
|
formula: |
C11 H12 N2 O2
|
name: |
TRYPTOPHAN
|
roles: |
chemical component
|
formula: |
C6 H15 N4 O2 1
|
name: |
ARGININE
|
roles: |
chemical component
|
formula: |
C5 H11 N O2 S
|
name: |
METHIONINE
|
roles: |
chemical component
|
formula: |
C4 H8 N2 O3
|
name: |
ASPARAGINE
|
roles: |
chemical component
|
formula: |
C6 H15 N2 O2 1
|
name: |
LYSINE
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roles: |
chemical component
|
formula: |
C9 H11 N O2
|
name: |
PHENYLALANINE
|
roles: |
chemical component
|
formula: |
C6 H10 N3 O2 1
|
name: |
HISTIDINE
|
roles: |
chemical component
|
formula: |
C3 H7 N O2 S
|
name: |
CYSTEINE
|
roles: |
chemical component
|
formula: |
C30 H36 N2 O4
|
name: |
1-[(1R,2R,3AS,3BS,10AR,10BS,11S,12AS)-1,11-DIHYDROXY-2,5,10A,12A-TETRAMETHYL-7-PHENYL-1,2,3,3A,3B,7,10,10A,10B,11,12,12A-DODECAHYDROCYCLOPENTA[5,6]NAPHTHO[1,2-F]INDAZOL-1-YL]-2-HYDROXYETHANONE
|
roles: |
chemical component
|
formula: |
H2 O
|
name: |
WATER
|
roles: |
chemical component
|
name: |
NR3C1, GRL
|
name: |
X-RAY DIFFRACTION
|
ID: |
pdb:3BQD
|
ID: |
rcsb:RCSB045836
|
accessURL: | https://files.rcsb.org/download/3BQD.xml.gz |
storedIn: |
Protein Data Bank
|
qualifier: |
gzip compressed
|
license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
format: |
PDBML/XML
|
accessType: |
download
|
authentication: |
none
|
authorization: |
none
|
accessURL: | https://files.rcsb.org/download/3BQD.pdb.gz |
storedIn: |
Protein Data Bank
|
qualifier: |
gzip compressed
|
license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
format: |
PDB Format
|
accessType: |
download
|
authentication: |
none
|
authorization: |
none
|
accessURL: | https://files.rcsb.org/download/3BQD.cif.gz |
storedIn: |
Protein Data Bank
|
qualifier: |
gzip compressed
|
license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
format: |
PDBx/mmCIF
|
accessType: |
download
|
authentication: |
none
|
authorization: |
none
|
accessURL: | http://www.rcsb.org/pdb/download/downloadFile.do?fileFormat=FASTA&compression=NO&structureId=3BQD |
storedIn: |
Protein Data Bank
|
license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
format: |
FASTA
|
accessType: |
download
|
authentication: |
none
|
authorization: |
none
|
accessURL: | https://files.rcsb.org/download/3BQD-sf.cif.gz |
storedIn: |
Protein Data Bank
|
qualifier: |
gzip compressed
|
license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
format: |
CIF
|
accessType: |
download
|
authentication: |
none
|
authorization: |
none
|
accessURL: | https://files.rcsb.org/download/3BQD.pdb1.gz |
storedIn: |
Protein Data Bank
|
qualifier: |
gzip compressed
|
license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
format: |
PDB Format (A)
|
accessType: |
download
|
authentication: |
none
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authorization: |
none
|
accessURL: | http://www.rcsb.org/pdb/explore/jmol.do?structureId=3BQD&bionumber=1 |
storedIn: |
Protein Data Bank
|
license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
format: |
JSmol
|
accessType: |
view
|
authentication: |
none
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authorization: |
none
|
abbreviation: |
wwPDB
|
homePage: | http://www.wwpdb.org |
ID: |
SCR:006555
|
name: |
Worldwide Protein Data Bank
|
abbreviation: |
PDB
|
homePage: | http://www.rcsb.org/pdb/![]() |
ID: |
SCR:012820
|
name: |
Protein Data Bank
|
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