biomedical and healthCAre Data Discovery Index Ecosystem
biomedical and healthCAre Data Discovery Index Ecosystem
| Title: | Structure of the C13.28 RNA Aptamer Bound to the G Protein-Coupled Receptor Kinase 2-Heterotrimeric G Protein Beta 1 and Gamma 2 Subunit Complex
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| description: |
Beta-adrenergic receptor kinase 1 (E.C.2.7.11.15), Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
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| privacy: |
not applicable
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| aggregation: |
instance of dataset
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| ID: |
PDB:3UZS
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| refinement: |
curated
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| keywords: |
TRANSFERASE/RNA
Protein-RNA complex
Protein Kinase Fold
RGS Homology Domain
Pleckstrin Homology Domain
beta propeller
G Protein-Coupled Receptor Phosphorylation
RNA Aptamer
Carboxymethylation
geranylgeranylation
TRANSFERASE-RNA complex
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| creators: |
Tesmer, V.M.
Lennarz, S.
Mayer, G.
Tesmer, J.J.
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| availability: |
available
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| types: |
structure
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| name: |
Bos taurus
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| ID: |
ncbitax:9913
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| name: |
Bos taurus
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| ID: |
ncbitax:9913
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| name: |
Bos taurus
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| ID: |
ncbitax:9913
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| name: |
Spodoptera frugiperda
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| ID: |
ncbitax:7108
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| name: |
Trichoplusia ni
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| ID: |
ncbitax:7111
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| name: |
Trichoplusia ni
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| ID: |
ncbitax:7111
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| authors: |
Tesmer, V.M.
Lennarz, S.
Mayer, G.
Tesmer, J.J.
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| alternateID: |
doi:10.1016/j.str.2012.05.002
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| year: |
2012
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| ID: | pmid:22727813 |
| title: |
Molecular mechanism for inhibition of g protein-coupled receptor kinase 2 by a selective RNA aptamer.
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| formula: |
C3 H7 N O3
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| name: |
SERINE
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| roles: |
chemical component
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| formula: |
C6 H15 N2 O2 1
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| name: |
LYSINE
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| roles: |
chemical component
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| formula: |
C6 H13 N O2
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| name: |
ISOLEUCINE
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| roles: |
chemical component
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| formula: |
C6 H13 N O2
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| name: |
LEUCINE
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| roles: |
chemical component
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| formula: |
C5 H9 N O2
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| name: |
PROLINE
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| roles: |
chemical component
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| formula: |
C5 H9 N O4
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| name: |
GLUTAMIC ACID
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| roles: |
chemical component
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| formula: |
C6 H15 N4 O2 1
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| name: |
ARGININE
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| roles: |
chemical component
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| formula: |
C5 H11 N O2
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| name: |
VALINE
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| roles: |
chemical component
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| formula: |
C5 H11 N O2 S
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| name: |
METHIONINE
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| roles: |
chemical component
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| formula: |
C5 H10 N2 O3
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| name: |
GLUTAMINE
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| roles: |
chemical component
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| formula: |
C9 H11 N O3
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| name: |
TYROSINE
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| roles: |
chemical component
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| formula: |
C4 H7 N O4
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| name: |
ASPARTIC ACID
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| roles: |
chemical component
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| formula: |
C2 H5 N O2
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| name: |
GLYCINE
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| roles: |
chemical component
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| formula: |
C4 H9 N O3
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| name: |
THREONINE
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| roles: |
chemical component
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| formula: |
C9 H11 N O2
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| name: |
PHENYLALANINE
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| roles: |
chemical component
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| formula: |
C3 H7 N O2 S
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| name: |
CYSTEINE
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| roles: |
chemical component
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| formula: |
C6 H10 N3 O2 1
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| name: |
HISTIDINE
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| roles: |
chemical component
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| formula: |
C3 H7 N O2
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| name: |
ALANINE
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| roles: |
chemical component
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| formula: |
C4 H8 N2 O3
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| name: |
ASPARAGINE
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| roles: |
chemical component
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| formula: |
C11 H12 N2 O2
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| name: |
TRYPTOPHAN
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| roles: |
chemical component
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| formula: |
C4 H9 N O2 S
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| name: |
O-METHYLCYSTEINE
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| roles: |
chemical component
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| formula: |
C10 H14 N5 O8 P
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| name: |
GUANOSINE-5'-MONOPHOSPHATE
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| roles: |
chemical component
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| formula: |
C9 H14 N3 O8 P
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| name: |
CYTIDINE-5'-MONOPHOSPHATE
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| roles: |
chemical component
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| formula: |
C10 H14 N5 O7 P
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| name: |
ADENOSINE-5'-MONOPHOSPHATE
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| roles: |
chemical component
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| formula: |
C9 H13 N2 O9 P
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| name: |
URIDINE-5'-MONOPHOSPHATE
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| roles: |
chemical component
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| formula: |
MG 2
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| name: |
MAGNESIUM ION
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| roles: |
chemical component
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| name: |
ADRBK1, GRK2
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| name: |
GNB1
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| name: |
GNG2
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| name: |
X-RAY DIFFRACTION
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| ID: |
pdb:3UZS
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| ID: |
ndb:NA1485
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| ID: |
rcsb:RCSB069414
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| accessURL: | https://files.rcsb.org/download/3UZS.xml.gz |
| storedIn: |
Protein Data Bank
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| qualifier: |
gzip compressed
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| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
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| format: |
PDBML/XML
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| accessType: |
download
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| authentication: |
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| authorization: |
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| accessURL: | https://files.rcsb.org/download/3UZS.pdb.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
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| accessURL: | https://files.rcsb.org/download/3UZS.cif.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
PDBx/mmCIF
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| accessType: |
download
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| authentication: |
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| authorization: |
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| accessURL: | http://www.rcsb.org/pdb/download/downloadFile.do?fileFormat=FASTA&compression=NO&structureId=3UZS |
| storedIn: |
Protein Data Bank
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
FASTA
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| accessType: |
download
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| authentication: |
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| accessURL: | https://files.rcsb.org/download/3UZS-sf.cif.gz |
| storedIn: |
Protein Data Bank
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| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
CIF
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| accessType: |
download
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| accessURL: | https://files.rcsb.org/download/3UZS.pdb1.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
PDB Format (A)
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| accessType: |
download
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| authentication: |
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| accessURL: | http://www.rcsb.org/pdb/explore/jmol.do?structureId=3UZS&bionumber=1 |
| storedIn: |
Protein Data Bank
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
JSmol
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| accessType: |
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| authentication: |
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| abbreviation: |
wwPDB
|
| homePage: | http://www.wwpdb.org |
| ID: |
SCR:006555
|
| name: |
Worldwide Protein Data Bank
|
| abbreviation: |
PDB
|
| homePage: | http://www.rcsb.org/pdb/ |
| ID: |
SCR:012820
|
| name: |
Protein Data Bank
|
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