biomedical and healthCAre Data Discovery Index Ecosystem
biomedical and healthCAre Data Discovery Index Ecosystem
| Title: | Crystal structure of Fab H5M9 in complex with influenza virus hemagglutinin from A/Viet Nam/1203/2004 (H5N1)
|
| description: |
Hemagglutinin HA1 chain, H5M9 antibody, light chain (kappa), Hemagglutinin HA2 chain, H5M9 antibody, heavy chain (IgG1)
|
| privacy: |
not applicable
|
| aggregation: |
instance of dataset
|
| ID: |
PDB:4MHH
|
| refinement: |
curated
|
| keywords: |
VIRAL PROTEIN/IMMUNE SYSTEM
H5N1 influenza virus
broadly neutralizing murine antibody
escape mutant
passive immunotherapy
VIRAL PROTEIN-IMMUNE SYSTEM complex
|
| creators: |
Zhu, X.
Guo, Y.H.
Jiang, T.
Wang, Y.D.
Chan, K.H.
Li, X.F.
Yu, W.
McBride, R.
Paulson, J.C.
Yuen, K.Y.
Qin, C.F.
Che, X.Y.
Wilson, I.A.
|
| availability: |
available
|
| types: |
structure
|
| strain: |
A/viet nam/1203/2004
|
| name: |
Influenza A virus
|
| ID: |
ncbitax:284218
|
| strain: |
A/viet nam/1203/2004
|
| name: |
Mus musculus
|
| ID: |
ncbitax:10090
|
| strain: |
Hi5
|
| name: |
Influenza A virus
|
| ID: |
ncbitax:284218
|
| strain: |
Hi5
|
| name: |
Mus musculus
|
| ID: |
ncbitax:10090
|
| name: |
Trichoplusia ni
|
| ID: |
ncbitax:7111
|
| name: |
Trichoplusia ni
|
| ID: |
ncbitax:7111
|
| authors: |
Zhu, X.
Guo, Y.H.
Jiang, T.
Wang, Y.D.
Chan, K.H.
Li, X.F.
Yu, W.
McBride, R.
Paulson, J.C.
Yuen, K.Y.
Qin, C.F.
Che, X.Y.
Wilson, I.A.
|
| alternateID: |
doi:10.1128/JVI.01577-13
|
| year: |
2013
|
| ID: | pmid:24049169 |
| title: |
A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.
|
| formula: |
C4 H7 N O4
|
| name: |
ASPARTIC ACID
|
| roles: |
chemical component
|
| formula: |
C5 H9 N O2
|
| name: |
PROLINE
|
| roles: |
chemical component
|
| formula: |
C2 H5 N O2
|
| name: |
GLYCINE
|
| roles: |
chemical component
|
| formula: |
C5 H10 N2 O3
|
| name: |
GLUTAMINE
|
| roles: |
chemical component
|
| formula: |
C6 H13 N O2
|
| name: |
ISOLEUCINE
|
| roles: |
chemical component
|
| formula: |
C3 H7 N O2 S
|
| name: |
CYSTEINE
|
| roles: |
chemical component
|
| formula: |
C9 H11 N O3
|
| name: |
TYROSINE
|
| roles: |
chemical component
|
| formula: |
C6 H10 N3 O2 1
|
| name: |
HISTIDINE
|
| roles: |
chemical component
|
| formula: |
C3 H7 N O2
|
| name: |
ALANINE
|
| roles: |
chemical component
|
| formula: |
C4 H8 N2 O3
|
| name: |
ASPARAGINE
|
| roles: |
chemical component
|
| formula: |
C3 H7 N O3
|
| name: |
SERINE
|
| roles: |
chemical component
|
| formula: |
C4 H9 N O3
|
| name: |
THREONINE
|
| roles: |
chemical component
|
| formula: |
C5 H9 N O4
|
| name: |
GLUTAMIC ACID
|
| roles: |
chemical component
|
| formula: |
C5 H11 N O2
|
| name: |
VALINE
|
| roles: |
chemical component
|
| formula: |
C5 H11 N O2 S
|
| name: |
METHIONINE
|
| roles: |
chemical component
|
| formula: |
C6 H15 N2 O2 1
|
| name: |
LYSINE
|
| roles: |
chemical component
|
| formula: |
C6 H13 N O2
|
| name: |
LEUCINE
|
| roles: |
chemical component
|
| formula: |
C6 H15 N4 O2 1
|
| name: |
ARGININE
|
| roles: |
chemical component
|
| formula: |
C11 H12 N2 O2
|
| name: |
TRYPTOPHAN
|
| roles: |
chemical component
|
| formula: |
C9 H11 N O2
|
| name: |
PHENYLALANINE
|
| roles: |
chemical component
|
| formula: |
C8 H15 N O6
|
| name: |
N-ACETYL-D-GLUCOSAMINE
|
| roles: |
chemical component
|
| formula: |
C6 H12 O6
|
| name: |
ALPHA-D-MANNOSE
|
| roles: |
chemical component
|
| name: |
HA
|
| name: |
HA
|
| name: |
X-RAY DIFFRACTION
|
| ID: |
pdb:4MHH
|
| ID: |
rcsb:RCSB081916
|
| accessURL: | https://files.rcsb.org/download/4MHH.xml.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
PDBML/XML
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | https://files.rcsb.org/download/4MHH.pdb.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
PDB Format
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | https://files.rcsb.org/download/4MHH.cif.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
PDBx/mmCIF
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | http://www.rcsb.org/pdb/download/downloadFile.do?fileFormat=FASTA&compression=NO&structureId=4MHH |
| storedIn: |
Protein Data Bank
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
FASTA
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | https://files.rcsb.org/download/4MHH-sf.cif.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
CIF
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | https://files.rcsb.org/download/4MHH.pdb1.gz |
| storedIn: |
Protein Data Bank
|
| qualifier: |
gzip compressed
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
PDB Format (A)
|
| accessType: |
download
|
| authentication: |
none
|
| authorization: |
none
|
| accessURL: | http://www.rcsb.org/pdb/explore/jmol.do?structureId=4MHH&bionumber=1 |
| storedIn: |
Protein Data Bank
|
| license: |
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
|
| format: |
JSmol
|
| accessType: |
view
|
| authentication: |
none
|
| authorization: |
none
|
| abbreviation: |
wwPDB
|
| homePage: | http://www.wwpdb.org |
| ID: |
SCR:006555
|
| name: |
Worldwide Protein Data Bank
|
| abbreviation: |
PDB
|
| homePage: | http://www.rcsb.org/pdb/ |
| ID: |
SCR:012820
|
| name: |
Protein Data Bank
|
Crystal structure of Fab H5M9 in complex with influenza virus hemagglutinin...
Crystal Structure of Fab CR9114 in Complex with a H5N1 influenza virus hema...
Crystal structure of a H5N1 influenza virus hemagglutinin from A/goose/Guan...
Crystal structure of antibody 1F1 bound to the 1918 influenza hemagglutinin...
Crystal Structure of Broadly Neutralizing Antibody CR8020 Bound to the Infl...
Crystal structure of aerosol transmissible influenza H5 hemagglutinin mutan...