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Title: Structure of the eukaryotic replicative CMG helicase and pumpjack motion      
description:
Cell division control protein 45, DNA replication complex GINS protein SLD5, DNA replication complex GINS protein PSF2, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF3, DNA replication licensing factor MCM3 (E.C.3.6.4.12), DNA replication licensing factor MCM2 (E.C.3.6.4.12), Minichromosome maintenance protein 5 (E.C.3.6.4.12), DNA replication licensing factor MCM7 (E.C.3.6.4.12), DNA replication licensing factor MCM4 (E.C.3.6.4.12), DNA replication licensing factor MCM6 (E.C.3.6.4.12)
privacy:
not applicable
aggregation:
instance of dataset
ID:
PDB:3JC6
refinement:
curated
keywords:
REPLICATION
CMG helicase
Cryo-EM
creators:
Yuan, Z.
Bai, L.
Sun, J.
Georgescu, R.
Liu, J.
O'Donnell, M.E.
Li, H.
availability:
available
types:
structure
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
name:
Saccharomyces cerevisiae
ID:
ncbitax:4932
authors:
Yuan, Z.
Bai, L.
Sun, J.
Georgescu, R.
Liu, J.
O'Donnell, M.E.
Li, H.
alternateID:
doi:10.1038/nsmb.3170
year:
2016
ID: pmid:26854665
title:
Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
formula:
C5 H9 N O2
name:
PROLINE
roles:
chemical component
formula:
C4 H8 N2 O3
name:
ASPARAGINE
roles:
chemical component
formula:
C5 H11 N O2
name:
VALINE
roles:
chemical component
formula:
C3 H7 N O3
name:
SERINE
roles:
chemical component
formula:
C6 H15 N4 O2 1
name:
ARGININE
roles:
chemical component
formula:
C4 H9 N O3
name:
THREONINE
roles:
chemical component
formula:
C6 H13 N O2
name:
ISOLEUCINE
roles:
chemical component
formula:
C3 H7 N O2
name:
ALANINE
roles:
chemical component
formula:
C5 H9 N O4
name:
GLUTAMIC ACID
roles:
chemical component
formula:
C6 H13 N O2
name:
LEUCINE
roles:
chemical component
formula:
C6 H15 N2 O2 1
name:
LYSINE
roles:
chemical component
formula:
C9 H11 N O2
name:
PHENYLALANINE
roles:
chemical component
formula:
C9 H11 N O3
name:
TYROSINE
roles:
chemical component
formula:
C4 H7 N O4
name:
ASPARTIC ACID
roles:
chemical component
formula:
C2 H5 N O2
name:
GLYCINE
roles:
chemical component
formula:
C5 H11 N O2 S
name:
METHIONINE
roles:
chemical component
formula:
C6 H10 N3 O2 1
name:
HISTIDINE
roles:
chemical component
formula:
C3 H7 N O2 S
name:
CYSTEINE
roles:
chemical component
formula:
C5 H10 N2 O3
name:
GLUTAMINE
roles:
chemical component
formula:
C11 H12 N2 O2
name:
TRYPTOPHAN
roles:
chemical component
formula:
ZN 2
name:
ZINC ION
roles:
chemical component
name:
MCM2, YBL023C, YBL0438
name:
MCM3, YEL032W, SYGP-ORF23
name:
MCM4, CDC54, HCD21, YPR019W, YP9531.13
name:
MCM5, CDC46, YLR274W, L9328.1
name:
MCM6, YGL201C
name:
MCM7, CDC47, YBR202W, YBR1441
name:
CDC45, SLD4, YLR103C, L8004.11
name:
SLD5, YDR489W
name:
PSF2, YJL072C, HRF213, J1086
name:
PSF1, YDR013W, PZA208, YD8119.18
name:
PSF3, YOL146W
name:
ELECTRON MICROSCOPY
ID:
rcsb:RCSB160516
ID:
pdb:3JC6
accessURL: https://files.rcsb.org/download/3JC6.xml.gz
storedIn:
Protein Data Bank
qualifier:
gzip compressed
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
PDBML/XML
accessType:
download
authentication:
none
authorization:
none
accessURL: https://files.rcsb.org/download/3JC6.pdb.gz
storedIn:
Protein Data Bank
qualifier:
gzip compressed
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
PDB Format
accessType:
download
authentication:
none
authorization:
none
accessURL: https://files.rcsb.org/download/3JC6.cif.gz
storedIn:
Protein Data Bank
qualifier:
gzip compressed
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
PDBx/mmCIF
accessType:
download
authentication:
none
authorization:
none
accessURL: http://www.rcsb.org/pdb/download/downloadFile.do?fileFormat=FASTA&compression=NO&structureId=3JC6
storedIn:
Protein Data Bank
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
FASTA
accessType:
download
authentication:
none
authorization:
none
accessURL: https://files.rcsb.org/download/3JC6-sf.cif.gz
storedIn:
Protein Data Bank
qualifier:
gzip compressed
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
CIF
accessType:
download
authentication:
none
authorization:
none
accessURL: https://files.rcsb.org/download/3JC6.pdb1.gz
storedIn:
Protein Data Bank
qualifier:
gzip compressed
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
PDB Format (A)
accessType:
download
authentication:
none
authorization:
none
accessURL: http://www.rcsb.org/pdb/explore/jmol.do?structureId=3JC6&bionumber=1
storedIn:
Protein Data Bank
license:
Data files contained in the PDB archive (ftp://ftp.wwpdb.org) are free of all copyright restrictions and made fully and freely available for both non-commercial and commercial use. Users of the data should attribute the original authors of that structural data. By using the materials available in the PDB archive, the user agrees to abide by the conditions described in the PDB Advisory Notice.
format:
JSmol
accessType:
view
authentication:
none
authorization:
none
abbreviation:
wwPDB
homePage: http://www.wwpdb.org
ID:
SCR:006555
name:
Worldwide Protein Data Bank
abbreviation:
PDB
homePage: http://www.rcsb.org/pdb/
ID:
SCR:012820
name:
Protein Data Bank
  • S10 OD012272/OD/NIH HHS/United States

  • GM111472/GM/NIGMS NIH HHS/United States

  • GM115809/GM/NIGMS NIH HHS/United States

  • S10 RR025415/RR/NCRR NIH HHS/United States

  • Howard Hughes Medical Institute/United States

  • R01 GM111742/GM/NIGMS NIH HHS/United States

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